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The potential effectiveness of homemade topical spironolactone in treating hair loss, with studies suggesting it is more effective than finasteride and even minoxidil when used as monotherapy. The conversation also mentions that other anti-androgens are being developed which may soon hit the market.

Khalidsh1: Ok. I will upload one soon This user has been using a combination of oral minoxidil and finasteride, as well as topical minoxidil to treat their hair loss over the past nine months with significant progress. They have also observed thickening in other areas such as eyelashes and eyebrows.

Kintor Pharmaceutical's Phase 2 results with the drug Pyrilutamide, a potential alternative to 5-ARI drugs like Finasteride and Dutasteride but without the side effects. It could be used in combination with other topical treatments such as Minoxidil. The safety of the drug has been demonstrated in 6 months of use, however there are still questions about long term efficacy and systemic absorption.

A user who has seen improvements in their hair loss after taking finasteride and minoxidil once a day for 5 months. Other users offered advice and support, with some cautioning about potential side effects of the treatments.

A user's progress with using Minoxidil 5% twice daily, dermarolling 1.5mm once per week and ketoconazole 2% shampoo for 2.5 months. Other users have suggested that the user should also use finasteride in order to maintain their results.

User discusses using low dose topical finasteride without minoxidil for hair loss. Another user shares their experience with homemade 0.025% finasteride topical, shedding, and microneedling.

Finasteride is key for hair regrowth, supported by oral/topical minoxidil, Folexin, Nizoral/Head & Shoulders, and vitamin D. No side effects experienced; early intervention and patience are crucial.

A user's 8-month progress on finasteride for hair loss treatment, with plans to continue for a full year. The user experienced initial shedding and scalp itch, which subsided, leading to hair growth. Other users discussed the necessity of continuous treatment to maintain results.

Topical Dutasteride may halt hair loss and effectively treat androgenic alopecia. Combining low-dose oral Dutasteride with topical application could maximize regrowth and minimize side effects.

A user encouraged others experiencing hair loss to try shaving their heads, sharing their own positive experience despite briefly using finasteride and natural methods. Responses were mixed, with some supporting the decision and others suggesting treatments like minoxidil and finasteride, while many commented on the appearance changes.

The user "OP" shared their hair loss journey, detailing their treatment regimen, which includes topical minoxidil, dutasteride, various vitamins, keto shampoo, derma rolling, and oils. They experienced significant shedding around month 6 but believe it has stopped, with hair regrowth resuming.

Dutasteride takes 1-3 months to affect scalp DHT levels, not just a week. The prostate absorbs Dutasteride faster than the scalp due to different vascular networks and enzyme densities.

The conversation is about overcoming fear of finasteride/dutasteride for hair loss treatment. Users suggest starting with a small supply, noting side effects are rare and reversible, and emphasize personal comfort and confidence.

A user in Turkey was advised by a dermatologist to avoid finasteride due to its hormonal effects and was prescribed minoxidil, shampoo, and vitamins instead. The user is considering seeking another doctor's opinion or buying finasteride directly from a pharmacy.

Dr. Oscar Muñoz's hair loss treatment tier list suggests oral minoxidil and finasteride are highly effective, while topical treatments like RU58841 and microneedling are less effective. Users discuss the effectiveness of various treatments, with some favoring oral options for their practicality and higher response rates.

Topical finasteride results in plasma levels 100 times lower than oral finasteride, potentially reducing systemic side effects. Users report similar efficacy with fewer side effects, suggesting a preference for topical application.

A user shared a 10-month hair loss treatment update using oral dutasteride, topical minoxidil, topical finasteride, microneedling, biotin, and saw palmetto. Replies praised the progress and suggested additional treatments like tretinoin and RU58841.

A user stopped finasteride due to side effects and rapid hair loss, considering a hair system. Others suggested alternatives like dutasteride, minoxidil, and topical finasteride.

The conversation is about choosing between finasteride and minoxidil for hair loss treatment. Most users prefer finasteride, citing its effectiveness in stopping hair loss, while some mention using both for better results.

A user shared their excitement about starting finasteride for hair loss after trying various ineffective methods. Other users discussed their experiences with finasteride, including shedding phases and side effects, with one mentioning using topical finasteride and minoxidil.

A user shared a 3.5-month hair regrowth progress using Minoxidil, ketoconazole, and dermarolling, and has started taking oral finasteride to maintain gains. There was a significant initial hair shed, which is normal for these treatments.

A user is experiencing ongoing hair loss despite using 0.5mg dutasteride and 2.5mg oral minoxidil for several years and is seeking advice. Suggestions include ensuring correct diagnosis, checking for other health issues, considering finasteride, trying topical antiandrogens, and consulting a dermatologist.

A satirical post jokes about a user meeting a doctor at the zoo who praises finasteride (Fin) for hair loss treatment, claiming it has a low side-effect profile and is effective. Replies include humorous disbelief, comparisons to other risks, and some personal accounts of side effects from Fin.

The conversation discusses using a low dose of topical finasteride to achieve hair benefits with minimal systemic exposure. Users share experiences and opinions on dosing, systemic buildup, and side effects of both topical and oral finasteride.

The phase 3 trial results for Pyrilutamide showed no significant difference from the control treatment in increasing hair count, leading to the company halting its development. Users discussed their disappointment and skepticism about hair loss treatments, with some mentioning other treatments like Minoxidil, Finasteride, and RU58841.

The conversation is about the side effects of finasteride, including Post Finasteride Syndrome, with varied personal experiences and differing views on the credibility of information sources. Some participants also discuss using minoxidil as a hair loss treatment.

A user shared their positive experience with hair regrowth after 3 months of using 6% Minoxidil and 0.3% Finasteride spray. They experienced temporary erectile dysfunction but it resolved, although morning erections are less frequent.

The user, Virtual_Force3845, shared their progress pictures after using Hims Fin/Min Spray consistently for 3-4 months. They are excited about the progress and have not experienced any side effects. Other users in the conversation shared their own experiences and asked questions about the treatment.

DHT Itch and its link to balding, with various treatments such as finasteride being discussed. Members shared their experiences of scalp itch before and after taking 5AR inhibitors, and potential underlying causes such as seborrheic dermatitis were discussed.

A user's experience with the hair loss treatment Pyrilutamide KX-826, which has resulted in some side effects and shedding. The conversation also includes advice for baseline pictures and trying treatments for at least 6 months.