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      community Bile Acid-Mediated DHT Dysregulation Hypothesis

      in Research/Science  13 upvotes 2 months ago
      Elevated bile acids can inhibit the enzyme AKR1C2, leading to increased DHT levels, which may accelerate hair loss in those predisposed to androgenetic alopecia. Treatments mentioned include topical minoxidil and finasteride.

      community Does dutasteride stop hair loss forever?

      in Finasteride/Dutasteride  38 upvotes 2 months ago
      Dutasteride and finasteride can significantly slow or halt hair loss, with some users experiencing regrowth, but results vary. Lifestyle factors and individual genetic predispositions also play a role in hair loss outcomes.

      community Is this good improvement? 3-4 months in

      in Is this regrowth?  479 upvotes 2 months ago
      The user experienced increased hair density and thickness after 3-4 months using finasteride, minoxidil, dermastamping, ketoconazole, and biotin. They apply minoxidil right after dermastamping without any side effects or shedding.

      community Got my first batch of 0.5 dutasteride. Hesitant to start.

      in Finasteride/Dutasteride  3 upvotes 2 months ago
      The conversation discusses a user's hesitation to start dutasteride for hair loss while already using finasteride, minoxidil (both oral and topical), RU58841, and ketoconazole shampoo. The user plans to gradually transition from finasteride to dutasteride to minimize shedding, seeking advice and reassurance from others.

      community 1ish year on fin and no improvement

      in Is this regrowth?  86 upvotes 2 months ago
      The user has been using finasteride for over a year without improvement and recently started oral minoxidil. Suggestions include trying dutasteride and continuing minoxidil for potential regrowth.

      community 24M still losing on Dut and Oral Min

      in Update  26 upvotes 2 months ago
      A 24-year-old male is losing hair despite using dutasteride and oral minoxidil, with no regrowth from April to October 2024. He is considering increasing his dosage and looking for cheaper prescriptions, while others recommend consulting a trichologist or trying different treatments.

      community A little over two years on Dut

      in Finasteride/Dutasteride  59 upvotes 3 months ago
      A 23-year-old male has been using Dutasteride for over two years to address hair thinning, with some success in temple regrowth but continued thinning on top. He is considering adding Minoxidil to his routine and is contemplating lifestyle changes like quitting smoking and drinking to improve hair density.

      community Why is everyone not directly advised Dutasteride?

      in Finasteride/Dutasteride  168 upvotes 3 months ago
      Dutasteride is less commonly prescribed for hair loss because it is not FDA-approved for this purpose, unlike finasteride, which is more accessible and preferred due to fewer side effects. Dutasteride may be more effective in reducing DHT but has a longer half-life and potentially more significant side effects.

      community Feel like I'm a reasonably good responder

      in Is this regrowth?  274 upvotes 3 months ago
      The user "OP" reported significant hair regrowth using oral finasteride, oral and topical minoxidil, ketoconazole shampoo, and derma stamping. OP experienced initial shedding but no other side effects.

      community How to Keep Your Hair on Steroids

      in Treatment  18 upvotes 4 months ago
      To minimize hair loss while using steroids, use finasteride or dutasteride and apply topical anti-androgens like RU58841. Avoid high doses of hair-toxic steroids; prefer testosterone, nandrolone, and boldenone.

      community DHT is about to get smashed ….

      in Update  804 upvotes 4 months ago
      The conversation discusses hair loss treatments like topical finasteride with minoxidil, oral dutasteride, and essential oils. Oral treatments like dutasteride and finasteride are seen as more effective, though some prefer topicals to avoid side effects.

      community 20yo, dutasteride and minoxidil aren’t working

      in Finasteride/Dutasteride  117 upvotes 4 months ago
      A 20-year-old reports worsening hair loss despite using dutasteride and minoxidil, and considers a hair transplant. Users suggest continuing treatments, trying microneedling, ketoconazole shampoo, switching to finasteride, or adding tretinoin.

      community after several weeks of research, here's the stack I've decided on

      in Finasteride/Dutasteride  43 upvotes 5 months ago
      A 23-year-old experiencing diffuse hair thinning has chosen a treatment stack including topical finasteride, a blend of rosemary, peppermint, and pumpkin seed oils, procyanidine B2 spray, ketoconazole shampoo, and scalp massages. They avoid minoxidil due to family history of side effects and oral finasteride due to high estrogen levels.

      community DHT/Testosterone levels in scalp Fin VS Dut.

      in Finasteride/Dutasteride  66 upvotes 5 months ago
      Dutasteride raises scalp testosterone by 99%, which may not be ideal for those sensitive to all androgens. Some argue finasteride's balancing act might be better, while others believe dutasteride is superior for hair regrowth.

      community Fuck it, I’m ordering Pyri Topical

      in Product  12 upvotes 5 months ago
      A user plans to order Pyrilutamide for hair loss after losing ground on finasteride. Another user advises against buying from Hairliciously, suggesting Amazon instead.

      community 3months of taking 1mg of Finasteride

      in Progress Pictures  262 upvotes 5 months ago
      A user shared impressive hair regrowth results after three months of taking 1mg daily of finasteride. Other users commented on their experiences and the effectiveness of different treatments like minoxidil and dutasteride.

      community (30M) 3 years Fin and 10 months min

      in Progress Pictures  307 upvotes 5 months ago
      A user shared their progress using 1.25g finasteride daily for 3 years and 5g oral minoxidil for 10 months, reporting positive results. They seek advice on further improving their hairline, with no significant side effects mentioned.

      community Topical finasteride now the safest possible path?

      in Finasteride/Dutasteride  84 upvotes 5 months ago
      Topical finasteride is considered a safer option for hair regrowth with fewer systemic side effects compared to oral finasteride. Some users report similar efficacy and side effects between topical and oral treatments, while others prefer topical due to reduced systemic exposure.

      community one year progress on dutasteride

      in Progress Pictures  200 upvotes 6 months ago
      A user shared their one-year progress on dutasteride, noting fuller hair but persistent thinning at the crown. They sought advice on whether to resume minoxidil and in which form, while others inquired about their choice of dutasteride and its effects.