A user shared progress pictures showing significant hair regrowth after 3 months using a topical foam with 5% Minoxidil and 0.25% Finasteride. They plan to add derma rolling to their routine.
The conversation is about a user seeking help with hair regrowth treatments, specifically mentioning Setipiprant, Minoxidil, Finasteride, and RU58841. The user is trying to contact forum members for guidance on making and using these treatments.
A 22-year-old man experienced significant hair loss after stopping minoxidil and finasteride, causing emotional distress. He resumed these treatments and is considering dutasteride and microneedling to manage his hair loss.
David Barreto shared that a London-based research group is conducting a 12-month trial for a new nutraceutical treatment for pattern hair loss, designed with Dr. Carlos Puig. The trial aims to provide robust data, with results expected in 1-2 years, potentially representing a significant advancement since finasteride’s introduction in 1997.
A seven-year journey with Finasteride and Minoxidil for hair loss. The post includes progress pictures showing the effects of the treatments, which have led to impressive results.
The user lost ground on oral finasteride and plans to switch to topical finasteride/minoxidil and microneedling. They are curious if topical treatments are more effective than oral ones.
Dutasteride raises scalp testosterone by 99%, which may not be ideal for those sensitive to all androgens. Some argue finasteride's balancing act might be better, while others believe dutasteride is superior for hair regrowth.
The conversation discusses the effects of lowering DHT on hair loss and the importance of monitoring DHT levels during treatment. The user suggests that individual responses to DHT and hair loss treatments vary, and expresses a preference for topical treatments over oral medications due to concerns about systemic DHT reduction.
User discusses tight scalp causing hair loss and suggests treatments like scalp massages, PRP, saw palmetto, and eucapil. They share their experience with saw palmetto and eucapil and consider adding PRP and scalp massages for better results.
Minoxidil gains are not permanent without continued use, even with DHT suppression. Combining treatments like Dutasteride, Finasteride, and RU58841 may help maintain hair, but stopping Minoxidil typically results in hair loss.
Switching from finasteride to dutasteride can reduce scalpDHT levels more effectively. The discussion includes using minoxidil, finasteride, and RU58841 for hair loss treatment.
The conversation discusses the effectiveness of various doses of Dutasteride in reducing scalpDHT and its impact on hair count. Users shared personal experiences with hair loss treatments, including Dutasteride, Finasteride, and Minoxidil, with one reporting significant hair loss reduction using a combination of oral Dutasteride and topical Minoxidil and Finasteride.
How Finasteride and Dutasteride help reduce hair loss by reducing the amount of DHT in scalp areas, as well as discussing factors such as sensitivity to DHT, 5α-reductase expression in different parts of the hair follicle, and scalp tension.
The conversation discusses a last-resort hair loss treatment combining topical finasteride, minoxidil, melatonin, and progesterone, with claims that topical finasteride can inhibit up to 52% of scalpDHT. One reply clarifies that progesterone is not an anti-androgen but has anti-androgenic properties because it competes with androgens for receptors.
A Dutasteride Simulator predicts serum dutasteride, serum DHT, and scalpDHT levels using models from research papers. It simulates various dosing schedules to determine steady-state effects and visualizes outcomes, including hair growth-related scalpDHT suppression.
A dutasteride simulator predicts that daily 0.5 mg dosing results in higher DHT suppression compared to less frequent dosing. Twice-weekly dutasteride may be as effective as finasteride 5 mg, providing a balance between efficacy and ease of use.
Topical finasteride may reduce more scalpDHT but is seen as inconsistent and messy compared to oral finasteride. Users report mixed results with both forms, with some preferring oral for its convenience and consistent dosing, while others find topical effective but harder to apply.
The conversation is about whether 0.5 mg of finasteride reduces scalpDHT as effectively as 1 mg. Users suggest that even lower doses like 0.05 mg can significantly reduce scalpDHT.
Finasteride works by reducing DHT, which helps stop hair miniaturization. The user is on finasteride and believes it works due to its effect on growth factors and DHT reduction.
The conversation discusses the potential for high doses of dutasteride to completely inhibit scalpDHT and speculates whether this could cure baldness when combined with a topical antiandrogen. Specific dosages mentioned are 0.5 mg reducing scalpDHT by 55% and 2.5 mg by about 79%.
The conversation is about identifying ingredients in a scalp serum and their effects on DHT levels. The serum contains various ingredients like Aqua, Biotin, and Oleanolic Acid.
The user has been using topical finasteride and minoxidil for five months with little progress and is considering oral dutasteride to lower DHT levels, questioning if minoxidil is more effective with reduced DHT. They also use microneedling and tretinoin in their treatment routine.
The conversation discusses the effectiveness of different doses of Dutasteride (Dut) in reducing scalpDHT levels. It suggests that 1mg and 1.5mg doses would reduce scalpDHT by amounts between 51% and 79%.
Dutasteride and finasteride are effective for many in reducing hair loss by lowering DHT levels, though results vary based on individual sensitivity and genetics. Higher doses of dutasteride may not significantly increase hair growth due to diminishing returns, and topical finasteride is suggested as an alternative for some.
Serum DHT is mostly inactive; sebum DHT is a better measure for hair loss. Users discuss using finasteride, dutasteride, and topical treatments like KX826 and RU58841 for better scalpDHT suppression.
The conversation discusses the fluctuation of testosterone levels in men under 40 and the difference between serum DHT and scalpDHT. It also mentions that DHT levels are higher on Dutasteride than on Finasteride, which is unusual.
A user experienced increased hair shedding and unchanged DHT levels after taking 0.25mg of finasteride for 47 days, leading them to increase the dose to 0.5mg. Others discussed varying experiences with finasteride, minoxidil, and the importance of measuring scalpDHT.
The conversation discusses the scalp tension theory as a potential factor in hair loss, alongside DHT, inflammation, and other mechanisms. Treatments mentioned include finasteride, minoxidil, and botox injections, with some users exploring additional methods due to varying effectiveness.
User taking 1mg finasteride daily for 2 years, wants to block more scalpDHT. Seeks reference for additional topical DHT blockers like alfatradiol and fluridil.