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      community KX826 New Phase 3 Trial In China for 2025: 1.0% concentration

      in Research/Science  57 upvotes 1 month ago
      KX-826 is undergoing Phase III trials in China as a potential treatment for male pattern baldness, with some users considering it as an alternative or addition to finasteride and dutasteride. Opinions on its effectiveness vary, with some users reporting positive results and others finding it expensive and ineffective.

      community What do you mix your RU58841 powder with?

      in Product  1 upvotes 4 months ago
      RU58841 powder is mixed with a 70% ethanol and 30% propylene glycol solution, with some users seeking PG-free alternatives. Minoxidil is also mentioned as a treatment option.

      community What do you do about hairloss where scalp feels tight? Losing Hope

      in Chat  4 upvotes 7 months ago
      A 24-year-old male has been using 0.5mg finasteride, 5% minoxidil twice daily, iron and zinc supplements, derma rolling weekly, and Nizoral weekly for hair loss. Despite these treatments, he experiences tight, painful scalp areas with no progress and some hair loss.

      community Dim: high estradiol levels what to do

      in Chat  8 upvotes 7 months ago
      A user is experiencing facial bloating from low-dose topical finasteride due to high estradiol levels and is seeking advice on using DIM to manage this issue, including dosage and brand recommendations.

      community Sublingual topical minoxidil experience

      in Minoxidil  16 upvotes 3 years ago
      A user experienced severe side effects from using topical minoxidil sublingually, including muscle cramps, dizziness, and high potassium levels. They were advised to stop and seek medical help, emphasizing that topical minoxidil is not safe for ingestion due to its alcohol content.

      community 3 months on dutasteride/minoxidil progress

      in Progress Pictures  507 upvotes 1 month ago
      A user shared their 3-month progress using 0.5mg daily dutasteride and 3mg oral minoxidil for hair loss, reporting significant improvement after an initial shedding phase. The user experienced no side effects and noted that dutasteride might have fewer side effects than finasteride.

      community Is microneedling + minoxidil better than oral minoxidil

      in Chat  29 upvotes 4 months ago
      Oral minoxidil is considered more effective for hair regrowth than topical minoxidil, but it carries higher risks. Combining microneedling with topical minoxidil can enhance absorption, but oral minoxidil with microneedling shows significant results.

      community What's "wrong" with oral minoxidil, exactly?

      in Minoxidil  173 upvotes 4 months ago
      Oral minoxidil can boost hair growth but may cause side effects like heart palpitations and increased body hair. Many prefer topical minoxidil due to fewer side effects.

      community Dutasteride High Libido. How come we don't talk about this?

      in Finasteride/Dutasteride  210 upvotes 4 months ago
      Dutasteride and finasteride can affect libido differently, with some experiencing increased libido and others decreased libido or erectile dysfunction. Dutasteride may increase testosterone levels but can also cause side effects like liver enzyme changes, while topical finasteride may have fewer sexual side effects.

      community (30M) 3 years Fin and 10 months min

      in Progress Pictures  307 upvotes 7 months ago
      A user shared their progress using 1.25g finasteride daily for 3 years and 5g oral minoxidil for 10 months, reporting positive results. They seek advice on further improving their hairline, with no significant side effects mentioned.

      community 9 months oral min, 2 months topical min. Late 30s.

      in Progress Pictures  54 upvotes 8 months ago
      The user used oral finasteride, topical minoxidil foam, a derma roller, keto shampoo, Hims thick fix shampoo, hair dye, and rosemary oil for hair restoration. They reported no side effects and noted significant improvement, especially in the hairline.

      community Topical fin working when oral has failed?

      in Finasteride/Dutasteride  1 upvotes 9 months ago
      The user switched from oral finasteride to dutasteride with minoxidil, but saw no results. They then tried topical finasteride and noticed some potential improvement after four months, theorizing that the topical application bypasses liver metabolism.

      community Sunlight: Does it Stimulate Hair Growth or Hair Loss?

      in Research/Science  64 upvotes 10 months ago
      The conversation discusses whether sunlight exposure affects hair growth or loss, with mixed anecdotes and theories but no clear consensus. Some suggest moderate sunlight can benefit hair by providing vitamin D, while others doubt its effectiveness compared to treatments like Minoxidil or finasteride.

      community 48M, 11 month progress, 1MG finasteride only

      in Progress Pictures  627 upvotes 1 year ago
      A 48-year-old man's 11-month progress using 1mg finasteride for hair loss treatment, with significant improvement and no side effects. Other users share their experiences, with some also seeing positive results, while others have not been as successful.

      community HLT Megathread on HMI-115 (key takeaways in comments)

      in Research/Science  39 upvotes 2 years ago
      HMI-115, a newly discovered hair loss treatment that could potentially be effective for those with diffuse thinning and telogen effluvium. It is based on prolactin receptor antagonist signaling and has already undergone Phase I trials in women, with potential commercialization by 2027.

      community Opinion about my regiment.....

      in Treatment  6 upvotes 2 years ago
      A user shares their hair loss treatment regimen, which includes oral finasteride, oral and topical minoxidil, RU58841, LLLT cap, microneedling, ketoconazole shampoo, biotin, vitamin D3, NAC supplement, MK677, collagen, and other hair care products. They seek opinions on its effectiveness.

      community Dutasteride (.5mg) is some strong stuff!

      in Finasteride/Dutasteride  58 upvotes 3 years ago
      User switched from finasteride and minoxidil to dutasteride, experienced side effects, then took dutasteride once a week with improved hair density. Another user had success with daily dutasteride, while one had no results from topical dutasteride.

      community Tattooing Hair Loss Drugs into your Scalp

      in Treatment  104 upvotes 4 months ago
      Tattooing hair loss drugs like minoxidil and dutasteride into the scalp is discussed as an alternative to daily pills, with mixed opinions on its effectiveness and convenience. Some users report positive results, but concerns about cost, potential side effects, and the procedure's discomfort are noted.

      community We need actual hair loss studies on Epristeride

      in Research/Science  6 upvotes 4 months ago
      Epristeride is a selective 5 alpha reductase type 2 inhibitor that may reduce scalp DHT similarly to finasteride, with potentially fewer side effects. It is suggested that combining epristeride with finasteride or dutasteride could enhance hair loss treatment effectiveness.

      community Leaving minoxidil for only 1 hour on scalp - how to maximize effectiveness?

      in Minoxidil  2 upvotes 5 months ago
      The user is trying to maximize minoxidil's effectiveness by applying it for only one hour to avoid spreading it to furniture and pets, especially cats. They experience side effects when combining minoxidil with dermarolling and are considering alternatives like oral minoxidil or microneedling.