The conversation discusses why the difference between donor and balding hair isn't studied more to find a cure for hairloss. Treatments mentioned include Minoxidil, finasteride, and RU58841.
The conversation is about the effectiveness of Dutasteride (Dut) and Minoxidil (Min) in reversing hair thinning. The user has been using Dut for 3 months and Min for a couple of years, and while hair fall has reduced, thinning continues. Other users suggest that Dut can reverse hair thinning over time, possibly beyond a year, and the outcome depends on individual body reactions and the degree of hair miniaturization.
The conversation is about hairloss treatments, specifically minoxidil, finasteride, and dutasteride. The main advice is to start with finasteride and never stop minoxidil once started, as stopping can lead to significant hairloss.
A user who experienced hairloss after switching from finasteride to dutasteride and is seeking advice whether it is an indication the treatment isn't working. Replies suggest that shedding is common at first due to dutasteride's longer half-life, but patience may be necessary before results are seen.
Hairloss theory suggests imbalance between Vitamin D Receptor (VDR) and Androgen Receptor (AR) activation. Proposed treatment includes upregulating VDR, downregulating AR, and improving mitochondrial health.
The user tried dutasteride for hairloss for 2.5 years but experienced drastic thinning and receding hairline. They decided to switch back to finasteride, along with minoxidil, LLLT, and ketoconazole, due to dissatisfaction with dutasteride's results and side effects.
Hairloss theory involves 3alpha-hydroxysteroid reductase (3AHD) converting DHT to androstenol. Discussion explores potential treatments and encourages more research.
User tried DIY Dutasteride Mesotherapy for hairloss due to unsatisfactory Finasteride results. Used mesotherapy injection gun and liquid dutasteride for better results and fewer side effects.
The potential risks and benefits of using Dutasteride as a hairloss treatment, compared to using Finasteride or other treatments like RU58841 or Accutane. People discussed their personal experiences with these treatments and shared advice on how to proceed.
The user has been using finasteride for 18 years to manage hairloss and is considering starting minoxidil and possibly a hair transplant. Despite some regrowth, they are exploring additional treatments like dutasteride and oral minoxidil due to continued hair thinning.
Kintor's Pyrilutamide (KX-826) showed hair growth in Chinese Phase III trials but did not significantly outperform placebo. The treatment was safe with no major adverse reactions reported.
People shared mixed experiences with RU58841 for hairloss; one person saw no improvement, another had significant gains and uses it with finasteride, while a third had an allergic reaction to the premixed solution. Some mix RU58841 powder into minoxidil themselves.
Topical melatonin may improve hair density and thickness, and reduce hairloss and seborrhea with no significant side effects. The user made their own melatonin solution for hair treatment.
The conversation is about the effectiveness of topical melatonin for hairloss. No specific treatments were discussed, only a sarcastic suggestion to go to tropical places and eat coconuts.
A user shared their one-year results using finasteride and minoxidil for hairloss, showing noticeable improvement. They started seeing results at six months, using 1ml liquid twice a day and a pill once a day.
The user tried Finasteride, Dutasteride, Minoxidil, RU58841, dermarolling, and oral castor oil for hairloss. They found RU58841 and Minoxidil most effective with no side effects, while Finasteride and Dutasteride caused sexual side effects.
The user shared their experience with Finasteride and Dutasteride for hairloss. They initially had success with Finasteride but switched to Dutasteride after experiencing shedding, which continued, and are now considering a hair transplant.
A user shared a 60-day progress update on hair regrowth using only 5% Minoxidil foam once daily. Others suggested adding finasteride to address the underlying cause of hairloss and maintain long-term results.
Ketoconazole 2% shampoo stopped a user's severe hair shedding after just two uses, a result not achieved by finasteride or oral minoxidil. Some users suggest the shampoo's anti-androgenic properties may help with hairloss, while others think the shedding might have stopped naturally or due to the end of a shedding phase.
The progress made by someone using finasteride, minoxidil and Nizoral for hairloss over a 2.5 year period, with before and after photos to show the results. Replies included encouragements and questions about the treatments used.
A 24-year-old male has been using 0.5mg finasteride, 5% minoxidil twice daily, iron and zinc supplements, derma rolling weekly, and Nizoral weekly for hairloss. Despite these treatments, he experiences tight, painful scalp areas with no progress and some hairloss.
Topical finasteride as a potential alternative to oral finasteride for reducing DHT levels on the scalp with fewer side effects, and other hairloss treatments such as minoxidil.
The conclusion of the conversation is that the user, ZadarskiDrake, has been using minoxidil and finasteride for two years to treat hairloss. They apply minoxidil at night and have not experienced negative effects on muscle gains. They also mention using a needle pin for hair treatment.
Dutasteride takes 1-3 months to affect scalp DHT levels, not just a week. The prostate absorbs Dutasteride faster than the scalp due to different vascular networks and enzyme densities.
A user shared progress pictures showing successful hair retention using a low-dose topical finasteride (0.008%) combined with minoxidil. Users discussed the effectiveness of the treatment, minimal effective dosing, and avoiding systemic side effects.
The user has experienced significant hair thinning despite using 2.5 mg minoxidil for 2 years. Other users suggest adding finasteride or dutasteride and consulting a dermatologist for a proper diagnosis.
A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.
LemonyBonobo started oral minoxidil a week ago, experiencing significant shedding, and is concerned about potentially worsening their hair condition. They also use dutasteride, topical minoxidil, and dermarolling. Elyktronix, who has been on oral minoxidil for 15 months, recommends it, noting that shedding can be a positive response and that results take time.