community Amplifica Raised $26 Million to Continue Trials
Amplifica raised $26 million to advance its injectable treatments for hair growth. The funding will support the clinical development of their novel therapies.
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30 / 866 resultscommunity Fin raised my estrogen but also testosterone?
A user experienced initial side effects from finasteride, including erectile dysfunction and emotional changes, but later noticed increased muscle mass and assertiveness. Hormonal tests showed elevated estrogen and prolactin levels, which slightly decreased over time; the user plans lifestyle changes to see if they help.
community Does creatine raise DHT/ contribute to hairloss or is it purely placebo
Creatine may cause hair shedding in some individuals, but its impact on DHT and hair loss is debated. Many users report no link between creatine and hair loss, while others notice shedding despite using treatments like finasteride and minoxidil.
community Pelage Pharmaceutical Raises 120 million to continue PP405 Research. Link inside.
Pelage Pharmaceutical raised $120 million to continue research on PP405, a promising hair loss treatment that showed a 20% increase in hair density in 31% of men during a Phase 2a trial. The treatment was well-tolerated, with no systemic absorption, and Phase 3 trials are planned for 2026.
community How quickly does fin raise estradiol levels?
Finasteride can quickly raise estradiol levels by blocking DHT, allowing testosterone to convert to estrogen. Taking finasteride for just a few days can affect blood test results.
community Maybe a stupid question, but does anything that raises serum DHT also automatically raise scalp/follicle DHT?
Creatine may raise serum DHT but not necessarily scalp DHT, and its impact on hair loss is debated. Some users report hair shedding with creatine, while others see no effect.
community So does creatine boost libido, since it raises DHT?
Creatine may not significantly boost libido despite potentially raising DHT levels. Finasteride reduces DHT and may affect libido, but individual experiences vary.
community people on creatine and not on fin that hadn't experienced a raise in hair loss - do you even exist?
Creatine may increase hair loss, but some users on finasteride report no additional loss. One user on a finasteride, minoxidil, and microneedling regimen experienced no further hair loss while taking creatine.
community I was wrong about Dutastride. Let the I told you so comments rain in.
Switching from dutasteride to finasteride caused increased hair loss, dandruff, depression, and erectile dysfunction. The user plans to return to dutasteride, possibly with minoxidil, and is considering dosing strategies to manage side effects and regrowth.
community Creatine’s link to accelerating hair loss. Does any one have any lab work showing creatine raising DHT levels?
Creatine may increase DHT levels, potentially accelerating hair loss in those predisposed to male pattern baldness. Some users report no change in DHT when using creatine without training.
community 2 years after my HT. I couldn’t live with my hair anymore. It took so much effort every morning to style it properly, but just one gust of wind or a bit of rain was enough to ruin it for the rest of the day. I also really disliked how it looked in photos. I'm 32, so I still felt too young for this.
A 32-year-old had a hair transplant in Istanbul for 2500€, using 2800-3000 grafts, and is not using finasteride or other medications long-term. The user is satisfied with the results but acknowledges the possibility of needing another transplant in the future.
community PP405 Update and My Take on Pelage
Pelage Pharmaceuticals raised $120M for their hair loss treatment, PP405, showing strong investor confidence despite limited data. There is skepticism about its efficacy and long-term effects compared to treatments like GT20029.
community Connection between caffeine and hair loss?
Caffeine might raise stress hormones, potentially worsening hair loss. Telogen effluvium is often misattributed to minor stressors rather than significant life events.
community Does anyone know about the mechanism between creatine and 5-alpha reductase?
Creatine may raise DHT levels, potentially affecting hair loss, but its exact mechanism is unclear. Some users report that finasteride remains effective even when taking creatine.
community Recently took a hair screening blood test to check my vitals, got report and summarised it in gpt
The conversation discusses hair loss treatments, specifically using Minoxidil, finasteride, and RU58841. It also mentions the importance of raising vitamin D3 levels.
community What blood results (if any) could be affected by Fin/Min?
Finasteride can increase total testosterone and potentially raise estrogen levels, leading to side effects. Biotin in combined tablets can falsely elevate thyroid hormone levels in blood tests.
community British man dies after falling ill at hair transplant clinic in Turkey
A British man's death at a Turkish hair transplant clinic raised safety concerns about such clinics. Users discussed risks of cheaper clinics and suggested alternatives like Thailand, Korea, and Colombia.
community What is the cause of "DHT itch"?
The conversation discusses the effects of using Tongkat ali and dioscorea to raise DHT levels, leading to increased body hair growth and an itchy scalp, without causing hair loss. The discussion also debates the role of DHT in male characteristics and its impact on sexual function, with differing opinions on its importance and effects.
community Stop Complaining about Creatine. You're just fixated on shedding.
Creatine is unlikely to cause hair loss as it does not raise DHT levels. Hair loss is more likely due to genetics, medications, or lifestyle changes.
community L'Oréal Garnier discontinued stemoxydine serum so how can people still buy it?
L'Oréal Garnier discontinued their stemoxydine serum, raising concerns about the authenticity of products still sold online. Alternatives suggested include other brands' stemoxydine products, though some believe stemoxydine is ineffective.
community Does Oral Minoxidil Cause Collagen Impairment in the body?
Oral minoxidil may impact collagen production, raising concerns about tendon health. The user is worried about a potential link between oral minoxidil use and a tendon injury.
community If minoxidil inhibits collagen production, what does it do when it drips down your face during exercise?
Minoxidil may inhibit collagen production, raising concerns about its effects when it drips down the face during exercise. It's suggested to apply minoxidil before bed and wash it out before exercising.
community Hair getting destroyed 6 months into 0.5 mg Dut
The user switched from finasteride to dutasteride but experienced worsening hair loss, raising concerns about the effectiveness of the treatment. Some suggest combining finasteride and dutasteride or waiting longer for results, while others mention the possibility of shedding and recommend consulting a dermatologist.
community PP405 Never Worked: the follicles were already activated at baseline
PP405 was ineffective for hair growth as some follicles were already active before treatment, raising doubts about its efficacy. Users discussed other hair loss treatments like Minoxidil, finasteride, and RU58841, expressing skepticism and hope for future solutions.
community HairClone (UK) finally begins offering its Dermal Papilla Cell Hair Multiplication procedure to humans. In Guatemala.
HairClone is offering a Dermal Papilla Cell Hair Multiplication procedure in Guatemala, raising questions about its effectiveness and regulatory reasons for the location. Users express skepticism and curiosity about the treatment's success and potential costs.
community Oh my god for fucks sake why does creatine cause hair loss.. why can't no one possiblly come with why it causes hair loss
Creatine is debated for causing hair loss, with some users claiming it raises DHT levels, while others argue it has no significant effect. Despite conflicting opinions, some users report hair loss even when using DHT blockers like finasteride.
community Why there are no updates from Amplifica about SCUBE3 & AMP-303?
Amplifica has not provided updates on SCUBE3 and AMP-303, raising concerns about their trial outcomes. Users also mention other treatments like Minoxidil, finasteride, RU58841, PP405, and ET-03.
community About those dutasteride studies 😒
Dutasteride studies for hair loss are often sponsored by GlaxoSmithKline, raising concerns about potential bias. Despite this, some users report positive results with dutasteride and oral minoxidil, while others remain skeptical of industry-funded research.
community Has anyone tried Matrixyl 3000 topically for hair growth?
Matrixyl 3000 is discussed as a potential topical treatment for hair growth, but concerns are raised about excess collagen production being a consequence of hair loss. The conversation suggests that androgen-induced miniaturization leads to hair follicle death and skin fibrosis.
community Spironolactone to stop hair shedding
A doctor suggested spironolactone for hair shedding, but concerns were raised about its effectiveness and side effects compared to finasteride. The user plans to reduce testosterone dosage and start finasteride instead.