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GlossaryPyrilutamide

topical treatment blocking androgen receptors to combat hair loss

Pyrilutamide, also known as KX-826, is a topical non-steroidal anti-androgen being developed for the treatment of androgenetic alopecia (pattern hair loss). It works by blocking androgen receptors in hair follicles, which can help reduce hair loss and potentially promote hair regrowth.

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community Should I consider switching from Fluridil to Pyrilutmide?

in Treatment 10 upvotes 1 month ago

The conversation is about considering switching from Fluridil to Pyrilutamide for hair loss treatment. Pyrilutamide is suggested to be more effective, with a recommendation to use the 1% variant twice daily.

community Does anybody else have non-fin/min stacks that they feel are working?

in Progress Pictures 7 upvotes 1 year ago

The user is discussing their hair loss treatment stack, which includes CB-03-01, Fluridil, Alfatradiol, Cosmerna, microneedling, and Stemoxydine. They have seen some new hair growth but wish they could use finasteride.

community No fin/no min protocol. Pictures were 4.5 years apart. January 2019-June 2023. I am 28 years old was 23 in the first picture.

in Progress Pictures 3 upvotes 1 year ago

The post is about a user's progress pictures of their hair loss over a span of 4.5 years. They did not use finasteride or minoxidil for their hair loss treatment.

community Pyrilutamide (KX-826) progress?

in Is this regrowth? 13 upvotes 4 weeks ago

The user has been using pyrilutamide 0.5% for over 7 weeks, alongside dutasteride, and noticed some hair improvement, particularly at the temples. They plan to continue and possibly try a 1% solution, with no shedding or side effects reported.

community Pyrilutamide and RU alternatives?

in Treatment 1 upvotes 1 month ago

Pyrilutamide is officially available for purchase, and users suggest Fluridil as an alternative topical anti-androgen. Some users report positive results with pyrilutamide from Koshine.

community Pyrilutamide +Alfatradiol 0.1% , no Hairloss anymore

in Treatment 42 upvotes 1 month ago

OP experienced diffuse thinning for 11 years and used Minoxidil and Finasteride previously. They now use Pyrilutamide 0.5% and Alfatradiol 0.1%, resulting in significantly reduced hair loss.

community Pyrilutamide powder now sold at my local supermarket (Netherlands)

in Satire 2 months ago

Pyrilutamide powder is now available at a local supermarket in the Netherlands. The discussion humorously touches on hair loss treatments like Minoxidil, finasteride, and RU58841.

community Pyrilutamide, the molecule's true nature - Research

in Research/Science 13 upvotes 3 months ago

The conversation discusses Pyrilutamide for hair loss, with skepticism about its legitimacy and mentions of an upcoming press release from Kintor. It also references ongoing trials and includes links for further information.

community Pyrilutamide ,the molecule’s true nature

in Research 302 upvotes 3 months ago

Pyrilutamide is a selective AR antagonist with a high binding affinity, making it effective in competing with DHT for androgen receptors. The 1% concentration is more effective than the 0.5%, but the latter may suffice for mild hair loss; the drug is considered a good option for those avoiding 5AR blockers due to side effects.

community Pyrilutamide just launched internationally, and all you're doing is hating

in Product 3 months ago

The post and conversation are about the high cost and skepticism surrounding pyrilutamide as a hair loss treatment, with comparisons to minoxidil, finasteride, and RU58841. The original poster defends pyrilutamide's effectiveness and criticizes others for dismissing it without proper understanding.

community pyrilutamide 0.5% vs. ru58841 5%? is RU stronger because of the higher concentration?

in Technology 3 upvotes 3 months ago

The conversation is about comparing the effectiveness of 5% RU58841 and 0.5% pyrilutamide for hair loss treatment. The user is asking if the higher concentration of RU58841 makes it stronger than the lower dose of pyrilutamide.

community Is Pyrilutamide a failure? I'm just now catching up on the news regarding it for the first time in awhile.

in Research/Science 2 upvotes 3 months ago

Pyrilutamide appears to be ineffective for hair loss. Users discuss alternatives like Minoxidil, finasteride, and RU58841.

community Pyrilutamide isn’t failed at all.

in Technology 11 upvotes 5 months ago

Kintor is producing a cosmetic with KX826, starting at 0.5% concentration and moving to 1%. The 0.5% concentration wasn't as effective as minoxidil and finasteride, but the 1% concentration shows promise.

community Pyrilutamide stopping Minoxidil gains

in Chat 2 upvotes 7 months ago

Pyrilutamide is seen as effective for maintaining hair without regrowth, while Minoxidil is known for growing new hair but causes shedding of old hairs. There is a question if using Pyrilutamide would inhibit the hair regrowth effects of Minoxidil.

community Pyrilutamide phase 3 results and maintenance?

in Research/Science 4 upvotes 7 months ago

Pyrilutamide phase 3 results showed little to no significant hair regrowth, but may be sufficient for maintaining current hair density. The user is unsure due to lack of recent discussions on pyrilutamide.

community Best solution for pyrilutamide in UK?

in Treatment 9 months ago

The user is looking for a PG-free solvent in the UK or EU to make their own pyrilutamide solution for hair loss and is currently using finasteride, considering minoxidil. They hope pyrilutamide will help stabilize their hair loss.

community PYRILUTAMIDE progress in 15 months

in Progress Pictures 24 upvotes 10 months ago

The conversation discusses hair loss treatments, specifically the progress made with Pyrilutamide over 15 months. One person suggests using oral Minoxidil or Dutasteride, but another mentions experiencing negative side effects from oral Finasteride.

community Pyrilutamide Trial Phase 3 Results?

in Research/Science 10 upvotes 11 months ago

The conversation is about the release of Phase 3 trial results for pyrilutamide in China for treating hair loss. The user is inquiring if the actual results have been posted, noting that a recent release did not contain them.

community Pyrilutamide phase III clinical trial results released

in Research/Science 31 upvotes 11 months ago

Pyrilutamide did not show effectiveness in regrowing hair compared to a placebo, but it may still help maintain existing hair by preventing DHT from causing follicle miniaturization. Some users believe it could be beneficial when used with other treatments like minoxidil, finasteride, and dutasteride.

community PYRILUTAMIDE PHASE 3 RESULTS : No statistical significance

in Research/Science 122 upvotes 11 months ago

The phase 3 trial results for Pyrilutamide showed no significant difference from the control treatment in increasing hair count, leading to the company halting its development. Users discussed their disappointment and skepticism about hair loss treatments, with some mentioning other treatments like Minoxidil, Finasteride, and RU58841.

community Pyrilutamide kintor pharmaceutical

in Chat 6 upvotes 1 year ago

The conversation is about seeking information on GT20029 from Kintor Pharmaceutical as a potential hair loss cure and inquiring about experiences with CosmeaRNA.

community Pyrilutamide almost for 9 months

in Progress Pictures 62 upvotes 1 year ago

The user has been using pyrilutamide, topical finasteride, and 15% minoxidil for hair growth for almost 4 years. Despite mixed responses from others, the user reports seeing progress, especially with the addition of pyrilutamide, and plans to continue the regimen.

community Pyrilutamide / KX-826 | Discussion EU

in Research/Science 5 upvotes 1 year ago

The conversation is about a user expressing concerns over the safety of a new drug called Pyrilutamide (also known as KX-826) for hair loss. The user will only trust the drug if it's permitted by EU regulations and sold by a reputable company.

community A Technical Question About Pyrilutamide

in Research/Science 5 upvotes 1 year ago

Pyrilutamide is believed to be more effective than RU58841 and 1 mg finasteride in treating hair loss, with no systemic hormonal effects and the potential to block more than 31% of scalp DHT. It may also antagonize scalp testosterone due to its action as an androgen receptor antagonist.

community Pyrilutamide six months update{ New Progress Pics}

in Progress Pictures 321 upvotes 1 year ago

A user shared a six-month update on hair improvement using Pyrilutamide and Minoxidil, noting significant hair regrowth and strength. Some participants questioned the legitimacy of the results and the source of Pyrilutamide.

community Pyrilutamide potential release date!

in Update 9 upvotes 1 year ago

The conversation discusses the potential release date of a hair loss treatment called Pyrilutamide. One user suggests it may be available in about 5 years.

community Pyrilutamide 2 months update(with pics )

in Is this regrowth? 27 upvotes 1 year ago

The conversation discusses the effects of Pyrilutamide on hair growth after two months, with one person noting that while new hair regrowth isn't apparent, existing hair appears longer and thicker.

community Pyrilutamide : what's the current plan for mainstream product release

in Research/Science 1 upvotes 1 year ago

Pyrilutamide's mainstream product release date is discussed. Side effects found in studies are also questioned.

community Pyrilutamide release in Europe?

in Treatment 2 upvotes 1 year ago

User asks about Pyrilutamide release in Europe, specifically Germany, and considers importing it from China. No specific treatments mentioned.

community Pyrilutamide or RU Monotherapy?

in Treatment 6 upvotes 1 year ago

Using Pyrilutamide or RU as monotherapy for hair loss? Share experiences.