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GlossaryPyrilutamide

topical treatment blocking androgen receptors to combat hair loss

Pyrilutamide, also known as KX-826, is a topical non-steroidal anti-androgen being developed for the treatment of androgenetic alopecia (pattern hair loss). It works by blocking androgen receptors in hair follicles, which can help reduce hair loss and potentially promote hair regrowth.

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community Finally about to start Pyriltamide (ONLY Pyriltamide)

in Chat 63 upvotes 4 months ago

A user is excited to start using Pyriltamide for hair loss after experiencing side effects from topical finasteride. Other users discuss the potential and skepticism of Pyriltamide compared to older treatments like finasteride and RU58841.

community How to take better of my hair?

in Chat 2 upvotes 3 weeks ago

The user is experiencing hair loss and has tried topical finasteride without success due to side effects. They are considering using essential oils like rosemary, castor, and peppermint, and have started using 0.5% Pyriltamide.

community I think it’s time to drop Pyrilutamide at this point?….

in Update 35 upvotes 1 year ago

A user who has been using Pyrilutamide for 5 months with no results, and other users suggesting they switch to RU58841 or stick to their treatment plan for at least one year.

community Kintors 1% Pyrilutamide comes in October/November

in Treatment 21 upvotes 4 months ago

Kintor's 1% Pyrilutamide will be released in October/November. The user cannot tolerate finasteride.

community AnagenInc says GT20029 is possible now

in Research/Science 117 upvotes 1 year ago

AnagenInc is ready to produce a hair loss treatment called GT20029 if there is enough demand. People are discussing combining it with other treatments like finasteride and minoxidil, and some are concerned about the legitimacy and safety of gray market products.

community My Pyrilutamide Experience Photos

in Update 602 upvotes 2 years ago

A user's experience with Pyrilutamide, a topical treatment for hair loss that they used in combination with other treatments such as Minoxidil and Finasteride. The user experienced impressive results in a short amount of time.

community Pyrilutamide vs fluridil - which is better?

in Research/Science 2 upvotes 4 days ago

Fluridil and pyrilutamide are equally effective in stabilizing hair loss, with no regrowth observed. The user also uses dutasteride and minoxidil in their treatment.

community Anyone know by what percentage Pyrilutamide or Ru decrease your androgens?

in Chat 1 upvotes 2 weeks ago

Pyrilutamide and RU58841 are androgen receptor antagonists that block receptors without significantly reducing testosterone or DHT levels. Any indirect effect on androgen levels is likely negligible.

community Anyone on Pyrilutamide 1%? What do you think of it?

in Chat 3 upvotes 3 weeks ago

Pyrilutamide 1% is being used for hair loss, with some users experiencing shedding but no regrowth yet. It may be too early to see results.

community Pyrilutamide from RUdirect, legit or fake?

in Product 5 upvotes 3 weeks ago

Pyrilutamide from RUdirect is discussed, with users sharing experiences and alternative sources like Koshinemall. Users mention using treatments like minoxidil, RU58841, and dutasteride for hair loss.

community Pyrilutamide (KX-826) progress?

in Is this regrowth? 17 upvotes 1 month ago

The user has been using pyrilutamide 0.5% for over 7 weeks, alongside dutasteride, and noticed some hair improvement, particularly at the temples. They plan to continue and possibly try a 1% solution, with no shedding or side effects reported.

community Pyrilutamide and RU alternatives?

in Treatment 1 upvotes 2 months ago

Pyrilutamide is officially available for purchase, and users suggest Fluridil as an alternative topical anti-androgen. Some users report positive results with pyrilutamide from Koshine.

community Pyrilutamide +Alfatradiol 0.1% , no Hairloss anymore

in Treatment 41 upvotes 2 months ago

OP experienced diffuse thinning for 11 years and used Minoxidil and Finasteride previously. They now use Pyrilutamide 0.5% and Alfatradiol 0.1%, resulting in significantly reduced hair loss.

community Pyrilutamide powder now sold at my local supermarket (Netherlands)

in Satire 3 months ago

Pyrilutamide powder is now available at a local supermarket in the Netherlands. The discussion humorously touches on hair loss treatments like Minoxidil, finasteride, and RU58841.

community Pyrilutamide, the molecule's true nature - Research

in Research/Science 13 upvotes 4 months ago

The conversation discusses Pyrilutamide for hair loss, with skepticism about its legitimacy and mentions of an upcoming press release from Kintor. It also references ongoing trials and includes links for further information.

community Pyrilutamide ,the molecule’s true nature

in Research 302 upvotes 4 months ago

Pyrilutamide is a selective AR antagonist with a high binding affinity, making it effective in competing with DHT for androgen receptors. The 1% concentration is more effective than the 0.5%, but the latter may suffice for mild hair loss; the drug is considered a good option for those avoiding 5AR blockers due to side effects.

community Pyrilutamide just launched internationally, and all you're doing is hating

in Product 4 months ago

The post and conversation are about the high cost and skepticism surrounding pyrilutamide as a hair loss treatment, with comparisons to minoxidil, finasteride, and RU58841. The original poster defends pyrilutamide's effectiveness and criticizes others for dismissing it without proper understanding.

community pyrilutamide 0.5% vs. ru58841 5%? is RU stronger because of the higher concentration?

in Technology 3 upvotes 4 months ago

The conversation is about comparing the effectiveness of 5% RU58841 and 0.5% pyrilutamide for hair loss treatment. The user is asking if the higher concentration of RU58841 makes it stronger than the lower dose of pyrilutamide.

community Is Pyrilutamide a failure? I'm just now catching up on the news regarding it for the first time in awhile.

in Research/Science 2 upvotes 4 months ago

Pyrilutamide appears to be ineffective for hair loss. Users discuss alternatives like Minoxidil, finasteride, and RU58841.

community Pyrilutamide isn’t failed at all.

in Technology 11 upvotes 6 months ago

Kintor is producing a cosmetic with KX826, starting at 0.5% concentration and moving to 1%. The 0.5% concentration wasn't as effective as minoxidil and finasteride, but the 1% concentration shows promise.

community Pyrilutamide stopping Minoxidil gains

in Chat 2 upvotes 8 months ago

Pyrilutamide is seen as effective for maintaining hair without regrowth, while Minoxidil is known for growing new hair but causes shedding of old hairs. There is a question if using Pyrilutamide would inhibit the hair regrowth effects of Minoxidil.

community Pyrilutamide phase 3 results and maintenance?

in Research/Science 4 upvotes 8 months ago

Pyrilutamide phase 3 results showed little to no significant hair regrowth, but may be sufficient for maintaining current hair density. The user is unsure due to lack of recent discussions on pyrilutamide.

community Best solution for pyrilutamide in UK?

in Treatment 10 months ago

The user is looking for a PG-free solvent in the UK or EU to make their own pyrilutamide solution for hair loss and is currently using finasteride, considering minoxidil. They hope pyrilutamide will help stabilize their hair loss.

community PYRILUTAMIDE progress in 15 months

in Progress Pictures 24 upvotes 10 months ago

The conversation discusses hair loss treatments, specifically the progress made with Pyrilutamide over 15 months. One person suggests using oral Minoxidil or Dutasteride, but another mentions experiencing negative side effects from oral Finasteride.

community Pyrilutamide Trial Phase 3 Results?

in Research/Science 10 upvotes 1 year ago

The conversation is about the release of Phase 3 trial results for pyrilutamide in China for treating hair loss. The user is inquiring if the actual results have been posted, noting that a recent release did not contain them.

community Despite its straightforward mrchanism of action, it looks like pyrilitamide doesn't help regrow hair like finasteride does.

in Research/Science 7 upvotes 1 year ago

Pyrilitamide (KX-826) did not show significant improvement in hair count compared to placebo after 6 months. It's unclear if it can maintain hair at baseline.

community Pyrilutamide phase III clinical trial results released

in Research/Science 31 upvotes 1 year ago

Pyrilutamide did not show effectiveness in regrowing hair compared to a placebo, but it may still help maintain existing hair by preventing DHT from causing follicle miniaturization. Some users believe it could be beneficial when used with other treatments like minoxidil, finasteride, and dutasteride.

community PYRILUTAMIDE PHASE 3 RESULTS : No statistical significance

in Research/Science 122 upvotes 1 year ago

The phase 3 trial results for Pyrilutamide showed no significant difference from the control treatment in increasing hair count, leading to the company halting its development. Users discussed their disappointment and skepticism about hair loss treatments, with some mentioning other treatments like Minoxidil, Finasteride, and RU58841.

community Pyrilutamide kintor pharmaceutical

in Chat 6 upvotes 1 year ago

The conversation is about seeking information on GT20029 from Kintor Pharmaceutical as a potential hair loss cure and inquiring about experiences with CosmeaRNA.

community Pyrilutamide almost for 9 months

in Progress Pictures 62 upvotes 1 year ago

The user has been using pyrilutamide, topical finasteride, and 15% minoxidil for hair growth for almost 4 years. Despite mixed responses from others, the user reports seeing progress, especially with the addition of pyrilutamide, and plans to continue the regimen.