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      community Difference: GT20029 vs CosmeRNA

      in Treatment  9 upvotes 1 year ago
      GT20029 and CosmeRNA are both potential hair loss treatments; GT20029 breaks down the androgen receptor, while CosmeRNA prevents its production. Continuous use is needed, but less frequently than current treatments like Minoxidil and Finasteride.

      community Overwhelming amount of anti-androgens

      in Female 1 year ago
      The conversation discusses the effectiveness of anti-androgens for hair loss, with a preference for topical treatments like RU58841 over oral options due to better scalp concentration and fewer side effects. Topical finasteride at 0.1% may provide some results, especially when combined with a topical androgen receptor antagonist like RU58841.

      community Shaved my head after 7 years of fighting hair loss

      in Shaved/buzzed  52 upvotes 1 year ago
      A user's decision to shave their head after struggling with hair loss for seven years, and the medications and treatments they are using to attempt regrowth. They also discuss potential future treatments that may come out in the near future.

      community (1 month pyrilutamide results) what I noticed: massive shedding phase around week 2. it was worse than finasteride and minoxidil shedding. no side effects other than headache the first time I applied it. I feel like it's working but still too soon to tell.

      in Research/Science  5 upvotes 1 year ago
      The user experienced significant hair shedding in the second week of using pyrilutamide, more so than with finasteride and minoxidil, and reported a headache after the first application. They believe the treatment may be working but acknowledge it's too early to confirm results.

      community Anyone excited for CosmeRNA coming this month?

      in Product  171 upvotes 1 year ago
      CosmeRNA, a new hair loss treatment, is expected to release soon and may become part of the "big three" treatments alongside finasteride and minoxidil. It works differently from finasteride by targeting androgen receptors in hair follicles, potentially offering fewer side effects.

      community The closest thing to a cure before hair cloning or genetic via?

      in Treatment  9 upvotes 1 year ago
      The conversation discusses using finasteride or dutasteride to reduce DHT, CosmeRNA to target androgen receptors, and Minoxidil as a vasodilator for hair growth. The regimen aims to maintain hair by addressing DHT-AR ratio and continuous Minoxidil use.

      community Results on 2 months of Dutasteride 0.5mg + 2.5mg Minoxidil

      in Progress Pictures  147 upvotes 1 year ago
      A user's results after two months of using Dutasteride and Minoxidil, alongside other treatments such as multivitamins, derma rolling, finasteride, topical minoxidil, Nizoral shampoo, Pyrithione zinc shampoo, hair vitamins, and rosemary oil. People in the conversation shared encouragement and discussed their own regimens for treating hair loss.

      community Brothers in baldness any news on pyrilutamide

      in Chat  12 upvotes 1 year ago
      The conversation is about the potential effectiveness of a hair loss treatment called pyrilutamide. One person has been using it since September and reports positive results.

      community All Drugs in Clinical Trials in 2023

      in Research/Science  68 upvotes 1 year ago
      12 companies having drugs or therapies in clinical trials during 2023, with various molecules and phases of trial; the probability that some may fail; and progress being made in the field.

      community Why is there more skepticism in RU than Pyrilutamide?

      in Chat  12 upvotes 1 year ago
      The conversation is about skepticism towards the hair loss treatments RU58841 and Pyrilutamide, with users discussing the lack of human testing for RU58841 and the ongoing trials for Pyrilutamide. Some users believe RU58841 has more anecdotal success, while others highlight Pyrilutamide's current research progress.

      community How to buy pyrilutamide in India

      in Product  15 upvotes 1 year ago
      Purchasing Pyrilutamide for hair loss treatment in India, and exploring the possibility of utilizing Minoxidil, Finasteride, and RU58841 as alternatives.

      community Kintor’s GT20029 Phase 1 success

      in Update  73 upvotes 1 year ago
      Kintor's GT20029, a treatment for hair loss, has completed Phase 1 successfully, showing promise as an androgen receptor degrader that could potentially regrow hair. It is considered more effective than Pyrilutamide, with infrequent dosing and minimal systemic absorption.

      community GT20029. Kintor Pharma’s Product

      in Research/Science  13 upvotes 2 years ago
      The conversation discusses GT20029, a compound by Kintor Pharma that degrades androgen receptors and is in trials, with potential as a hair loss cure. Another promising treatment mentioned is an antibody that blocks prolactin and has shown positive results in macaques.

      community No Luck Getting Rid Of The Itchy Scalp. What Now?

      in Chat  10 upvotes 2 years ago
      A user experienced a burning, itchy scalp and hair thinning despite trying finasteride, steroid cream, antihistamines, various shampoos, and supplements. They seek advice on relieving the itch, hoping it will improve hair health.

      community discouraged about pyrilutamide

      in Research/Science  11 upvotes 2 years ago
      Discouragement regarding Pyrilutamide, a drug in development for hair loss, and the potential side effects of Finasteride. People discussed anecdotal experiences with Pyrilutamide as well as suggestions to wait out Phase 3 trials before making any conclusions.

      community Pyrilutamide update number 3 - 1.5 months

      in Update  52 upvotes 2 years ago
      A user's update on their hair loss treatments, which included Minoxidil and finasteride; they are experiencing reduced shedding with minimal side effects. Other users provided additional advice to the poster based on their own experiences.

      community Anyone used Pyril? Any updates from existing users?

      in Research/Science  17 upvotes 2 years ago
      Researching the effectiveness of the hair loss treatment Pyril in comparison to other treatments such as Minoxidil, Finasteride, and RU58841. Replies suggest that users often fail to provide updates on their experience with Pyril.

      community Pyrilutamide update number 1 - 1 week use

      in Update  55 upvotes 2 years ago
      A user who is using Pyrilutamide, Finasteride, and a homemade topical solution to treat their hair loss. Replies mentioned the potential of Pyrilutamide being a "cure" for hair loss and a reminder that results may not be credited solely to it.

      community pyrilutamide any results so far?

      in Treatment  44 upvotes 2 years ago
      The hair loss treatment Pyrilutamide and whether it has had any results for users. Martinsahara is planning to buy some soon.

      community I'll defeat the norwood reaper with kitchen sink light

      in Treatment  26 upvotes 2 years ago
      A user who is using a combination of oral and topical treatments, including finasteride, minoxidil, pyrilutamide, dutasteride, microneedling, and ketoconazole shampoo in order to combat hair loss. Another user gave the original poster a word of warning about overusing the ketoconazole shampoo.

      community topical fluridil/eucapil + dut to block all DHT+T from scalp?

      in Treatment  7 upvotes 2 years ago
      User experienced slow gains with topical fin+min, switched to topical dut+min, and considered adding Eucapil. Another user suggested DUT may be less effective topically due to high molar mass and mentioned Fluridil as a weak anti-androgen that could help.