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People are using topical melatonin for diffuse thinning and retrograde alopecia. They are discussing the best brands and application methods.

Amplifica starting clinical trials for new hair loss drug. SCUBE3 protein discovered, stimulates hair growth, could be alternative to Minoxidil and Finasteride.

User considers trying AAPE for hair restoration, costing $700 for 6 months. Others discuss its potential effectiveness and mention a study with promising results.

Hair loss discussion includes treatments Minoxidil, Finasteride, and RU58841. HMI 115 shows anecdotal success in Phase I trial, users seek group buy for research chemical.

SCUBE3, a protein linked to hair growth in moles, was discovered over 25 years ago and is being developed by Amplifica for potential hair loss treatment. Concerns exist about SCUBE3's association with cancer, as it is a protein that promotes cell growth, which could potentially trigger cancer development if used for hair growth therapy.

A user with low iron levels is experiencing hair loss and is taking oral minoxidil and finasteride. Another user confirms that low ferritin can contribute to hair loss and recommends iron supplements.

Hair loss treatments include Finasteride, Minoxidil, Ketoconazole shampoo, and Microneedling. Additional options are Dutasteride, oral Minoxidil, and hair transplants.

A user is concerned about weight loss stagnation while using minoxidil and finasteride during a calorie-cutting diet. Responses suggest water retention or a weight loss plateau as possible causes.

Elevated bile acids can inhibit the enzyme AKR1C2, leading to increased DHT levels, which may accelerate hair loss in those predisposed to androgenetic alopecia. Treatments mentioned include topical minoxidil and finasteride.

A female, aged 17-18, is experiencing significant hair loss, feeling hopeless despite trying various treatments like leave-in conditioners, omega-3s, supplements, sulfate-free shampoo, and biotin. She is distressed as her hair continues to thin, affecting her body image and self-esteem.

The user "Venom7337" shared their progress with hair loss, mentioning the treatments they used: Dutasteride, Minoxidil, and Ketoconazole shampoo. They hope to see further improvement in hair density and hairline.

User got a hair transplant and it improved their life. Transplanted hair lasts, but medication like finasteride is needed to maintain non-transplanted hair.

Kintor's GT20029, a treatment for hair loss, has completed Phase 1 successfully, showing promise as an androgen receptor degrader that could potentially regrow hair. It is considered more effective than Pyrilutamide, with infrequent dosing and minimal systemic absorption.

Hair loss treatment with 5% minoxidil, 1mg finasteride, and 1.5mm dermarolling showed progress in two months, making user optimistic about regrowth.

The conversation discusses the approval of Kintor Pharmaceutical's AR-PROTAC (GT20029) for clinical trials in China for acne and androgenic alopecia. One user expresses optimism about new treatments being developed and seeks clarification on how the new drug works, specifically if it temporarily degrades the AR protein to reduce DHT sensitivity in hair follicles.

The user shared impressive hair growth results after 7 months using a regimen of dutasteride, topical minoxidil, and biotin, alongside a healthy lifestyle. The conversation humorously discusses extreme and unconventional hair loss treatments, with many users expressing amazement and curiosity about the progress.

A person improved hair loss from Norwood 3 to Norwood 2 using a topical formula with minoxidil, dutasteride, and tretinoin, plus oral minoxidil and red light therapy. There is skepticism about the treatment's effectiveness and concerns about misleading comparison photos.

A user shared a nine-month hair regrowth progress using 5mg oral Minoxidil and 1.25mg oral Finasteride daily, with noticeable improvement and no side effects, despite a high-protein diet, occasional smoking, and regular exercise. They also mentioned using keto shampoo and having naturally increased body hair by about 10%.

Treating hair loss with finasteride, minoxidil, RU58841, and Nizoral, and the progress of this treatment over a period of six months.

A user with low ferritin and zinc levels is asking if others have seen hair improvement after taking iron supplements. They were prescribed minoxidil and finasteride by their doctor.

A user shared their hair loss treatment routine, which includes oral and topical Minoxidil, dermarolling, Keto shampoo, multivitamins, Biotin, oils, protein intake, and water. Another user suggested adding finasteride and continuing the routine for 6-12 months.

Natural remedies to treat hair loss, such as polyphenols, apple peel extract, grape seed extract, green tea extract, peppermint oil, pumpkin seed oil, apigenin, Ginkgo biloba, red clover extract, olive leaf extract, Ecklonia Cava and Grateloupia elliptica. In addition, terpenes, carotenoids, and tocopherols were discussed as potential treatments.

A hair regrowth journey over the course of one year with treatments including finasteride, minoxidil, micro needling, minimum shampooing and occasional use of Nizoral (2%).

A user's progress in using medications such as finasteride and minoxidil, along with keto shampoo and microneedling, to treat their hair loss. Replies suggested that the user was seeing positive results quickly, but noted the heavy treatments used may cause extra shedding.

A user's progress with treating hair loss using finasteride, minoxidil and microneedling over the course of 7 months. Other comments suggested additional treatments such as toppik to help hide it in the meantime.

A 21-year-old was diagnosed with early-stage androgenetic alopecia and prescribed only minoxidil 5% and ketoconazole shampoo by a dermatologist, who advised against finasteride for now. The user is skeptical about starting minoxidil due to concerns about increased hair loss.

A 39-year-old shared a 17-month hair loss treatment update using Dutasteride, Minoxidil, Nizoral shampoo, and a 1.5mm derma roller, noticing significant results after 9-12 months. They also maintain a healthy lifestyle and manage side effects like dry skin with moisturizer.

Taking finasteride alone did not stop hair loss, but adding vitamin D3 and iron supplements improved hair coverage and quality. It's important to check and address deficiencies, but caution is advised with iron supplementation without medical guidance.

He Shou Wu (Fo Ti) extract was found to prolong the hair growth phase, inhibit 5-alpha-reductase (like finasteride), reduce androgen receptors, and increase growth factors, potentially outperforming minoxidil in recovering hair follicle size after DHT exposure. Two compounds, emodin and TSG, are identified as responsible for these effects and warrant further investigation.

SCUBE3 is available online but poses risks like tumor promotion and high costs. Users advise against using it due to health concerns and inefficacy as a standalone treatment.