A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.
User celebrates 2-year anniversary of 2500 FUE hair transplant procedure and worries about future hair loss. Others compliment the results and suggest using Dut and Min to maintain hair.
KX-826 (Pyrilutamide) being tested in the US for hair loss treatment and that they have found enough people to participate in phase II clinical trials. Other treatments discussed are Minoxidil, finasteride, and RU58841.
First patient dosed with Pyrilutamide (Kintor) Phase III for hair loss treatment. Pyrilutamide differs from approved treatments as it competes with DHT to bind hair follicles, potentially reducing side effects.
Start hair loss treatment as soon as you notice thinning to prevent further loss; finasteride and minoxidil are suggested treatments, with the option to switch to topical treatments if side effects occur. Some regret not starting treatment earlier, and maintaining current hair is more likely than regrowth.
A user was frustrated with delays in getting finasteride for hair loss, was prescribed minoxidil, and found a vitamin B7 deficiency. They are questioning if the deficiency could cause receded temples and considering finding a new dermatologist.
Hair loss theory involves 3alpha-hydroxysteroid reductase (3AHD) converting DHT to androstenol. Discussion explores potential treatments and encourages more research.
A user shared their 14-year experience with hair loss treatments, primarily using finasteride, minoxidil, and Nizoral. They highlighted the effectiveness of finasteride despite some side effects and emphasized the importance of early prevention and the potential for negative selection bias in online reviews.
The conversation discusses the effectiveness of AMSbzs supplements in significantly increasing hair count, weight, and keratin content. The user questions why this treatment isn't more widely known despite its impressive results.
The conversation discusses GT20029, a new topical drug for hair loss and acne without notable side effects, which has been accepted for investigational use in China. Some users express skepticism about the legitimacy of the company and the potential for other drugs like RU58841 to be developed due to patent expiration and lack of profitability.
Topical finasteride in a liposomal formulation reduces systemic absorption compared to ethanol solutions. The user is seeking sources for such products, noting that popular options like morr-f are not liposomal.
A user has been using Waterman's Grow Me Shampoo, which claims to have DHT blockers and promote hair growth. They've noticed potentially faster hair growth and some new hairs but are unsure if the product is effective or not.
A user decided to use a hair system after 10 years of hair loss, avoiding surgery and supplements due to potential side effects. They were nervous but hopeful for natural-looking results.
Minoxidil gains are not permanent without continued use, even with DHT suppression. Combining treatments like Dutasteride, Finasteride, and RU58841 may help maintain hair, but stopping Minoxidil typically results in hair loss.
The user noticed increased hair shedding after switching to a new Kirkland minoxidil with a different formula and is concerned about its effectiveness. They suspect the shedding might be linked to the new minoxidil rather than other factors like changing finasteride dosage or stopping RU58841.
A user tried various hair growth treatments, including drinking topical minoxidil, using oral minoxidil and finasteride, and applying GHK-Cu, growth hormone peptides, and liposomal sulforaphane. They experienced thicker hair, while others discussed the risks and benefits of these methods.
The user shared impressive hair regrowth results after one year using oral finasteride and minoxidil spray, despite skepticism from some about the authenticity of the progress. The user experienced minimal side effects, such as an itchy scalp, and emphasized the importance of consistent use for maintaining results.
A 24-year-old with male pattern baldness experienced side effects from oral finasteride and switched to a topical minoxidil/finasteride combination, later incorporating daily shampooing and scalp brushing to manage hair loss and dandruff. After initial shedding, the regimen led to reduced hair loss and new hair growth, with the user now using a densita mf combination (5% minoxidil/0.1% finasteride + redensyl) nightly.
KX-826 initially improves hair growth but declines after 24 weeks, with mild itching as a side effect. Combining it with minoxidil and finasteride may improve results, but long-term effectiveness is uncertain.
A user was embarrassed by a pharmacist's loud mention of "minoxidil" for hair loss, sparking a discussion on the stigma and unprofessionalism. Users suggested online purchases or different pharmacies for privacy and reassured that most people don't notice others' purchases.
There have been no new effective hair loss treatments since finasteride, despite technological advancements. Current treatments include finasteride, minoxidil, and RU58841, with ongoing challenges and potential future solutions in research.
Some users believe people falsely claim hair restoration results from finasteride and minoxidil alone, while actually having hair transplants. Finasteride and minoxidil, often used with microneedling and nizoral, are effective for many, but results and opinions on dosages vary.
The user reported positive progress in hair growth using Dutasteride 0.5 mg, Minoxidil 5%, and microneedling over 3.5 months. They plan to continue and improve their regimen for better results.
The user had high DHT levels after 8 months on dutasteride, questioning the drug's authenticity. They got dutasteride from a legitimate source and will update on progress.