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      community TDM-105795 phase 2 results are in!

      in Research/Science  28 upvotes 10 months ago
      TDM-105795 showed promising hair growth results, with higher efficacy than placebo and minimal side effects. It activates dormant hair follicle stem cells and may maintain gains without immediate loss, unlike minoxidil.

      community Pyrilutamide phase III clinical trial results released

      in Research/Science  31 upvotes 1 year ago
      Pyrilutamide did not show effectiveness in regrowing hair compared to a placebo, but it may still help maintain existing hair by preventing DHT from causing follicle miniaturization. Some users believe it could be beneficial when used with other treatments like minoxidil, finasteride, and dutasteride.

      community Setipiprant trial results

      in Update  11 upvotes 5 years ago
      Setipiprant trial for hair loss failed, showing no difference between placebo and treatment. Discussion also noted placebo users reporting side effects.

      community 35% regrowth brothers and sisters! More effective than Minox and Fin?

      in Treatment  107 upvotes 6 years ago
      A double-blind clinical study that found ingestion of tocotrienols resulted in a 34.5% increase in hair regrowth compared to the placebo group, and discussion about potential side effects and cost of supplementation with vitamin E pills. The conversation noted that it may be more effective than commonly used treatments like minoxidil and finasteride.

      community Breaking hair loss news! GT20029 is a resounding success!

      in Product  132 upvotes 8 months ago
      GT20029, a new hair loss treatment, shows promising results but only a slight improvement over placebo. People are cautiously optimistic, discussing its potential and combining it with existing treatments like Minoxidil and Finasteride.

      community KX-826 Phase 3 Failed. Sorry guys...

      in Research/Science  48 upvotes 1 year ago
      The conversation discusses the failure of Phase 3 trials for the hair loss treatment KX-826, with no significant difference found between the drug and placebo. Some users express disappointment and skepticism, while others discuss alternative treatments like Minoxidil, finasteride, and RU58841.

      community Exercise seems to be helping, a lot, quickly.

      in Chat  1 upvotes 2 months ago
      Exercise may be improving hair thickness and reducing thinning for a 50-year-old man using topical finasteride, minoxidil, Nizoral, and microneedling. The improvement could be due to exercise, the treatments, or a placebo effect.

      community Has pyrilutamide worked for anybody?

      in Product  1 upvotes 4 months ago
      The post discusses the effectiveness of pyrilutamide for hair loss. The user maintains hair with alfatrodial, fluridil, minoxidil, and keto shampoo but is seeking a simpler and cheaper alternative.

      community Average tressless user after taking oral minoxidil

      in Satire  1442 upvotes 1 year ago
      The conversation is about hair loss and the use of minoxidil (Minoxidil) and finasteride (Fin) as treatments. The conclusion is that some users have seen success in maintaining their hair with minoxidil, but there are varying opinions on the effectiveness of the treatments.

      community Saw palmetto, eucapil and micro needeling

      in Treatment  7 upvotes 2 years ago
      User noticed receding temples, used minoxidil and microneedling with positive results. Added saw palmetto and eucapil, experienced shedding and thinner hairline, but no side effects.

      community Anagenic Pyrilutamid, has anyone tried this?

      in Product  2 upvotes 10 months ago
      The conversation is about personal experiences with Anagenic Pyrilutamid for hair loss and what carriers people use with it. No specific treatments or outcomes are mentioned.

      community Is it possible that dutasteride won’t make you depressedd if finasteride did?

      in Chat  16 upvotes 8 months ago
      The conversation discusses whether dutasteride might cause less depression than finasteride for hair loss treatment, with some users suggesting it could due to different mechanisms of action or molecular size, while others express skepticism or share personal experiences with these medications.

      community Fin fuckbois to ascended masters

      in Satire  272 upvotes 1 year ago
      Hair loss treatments discussed include Minoxidil, Finasteride, microneedling, red light therapy, and biotin pills. The most proven treatments are Minoxidil, Finasteride, and microneedling, while other methods are considered less effective or satirical.

      community Why are low finasteride doses seen as highly ineffective, when studies show 0.05 mg/day to work?

      in Finasteride/Dutasteride  38 upvotes 2 years ago
      The efficacy of low doses of finasteride to reduce scalp DHT, and whether studies showing a 61% reduction are reflected in actual results. Replies discussed hair growth as an unintended consequence of minoxidil and finasteride use, as well as self-selective bias, potential side effects, and that studies measure effectiveness by hair count changes rather than DHT inhibition.

      community Just quit nicotine and caffeine

      in Treatment  20 upvotes 2 years ago
      The user has been using finasteride and oral minoxidil for hair loss but hasn't seen improvement and is quitting nicotine and caffeine to see if it helps. Some believe quitting nicotine improved their hair health due to better blood flow, while others are skeptical about the impact of blood flow on hair loss.

      community Switched to Dutasteride from Finasteride

      in Finasteride/Dutasteride  13 upvotes 1 month ago
      The user switched from finasteride to dutasteride and noticed less hair shedding, questioning if it's due to dutasteride's effects. Others shared mixed experiences with shedding and side effects after switching, with some seeing improvements and others experiencing continued shedding.

      community GT20029 - Promising phase II results

      in Research/Science  15 upvotes 7 months ago
      GT20029 showed significant hair growth and safety in phase II trials, with no adverse sexual events. Users are hopeful but concerned about future costs and systemic effects.

      community Kintor does not have abandoned KX-826 - ANNUAL RESULTS 2023

      in Product  8 upvotes 8 months ago
      The conversation discusses disappointment with the hair loss treatment KX-826 but notes that the company Kintor is still focused on developing and commercializing it, as stated in their 2023 annual report. The user questions the effectiveness of KX-826 in comparison to minoxidil's role in improving hair thickness and appearance.

      community Further prolactin research....

      in Research/Science  6 upvotes 10 months ago
      HMI 115 did not work as expected for hair regrowth in humans, unlike in macaque monkeys. There is anticipation for further research on prolactin's role in hair loss, with expectations that pharmaceutical companies will likely solve this before universities.