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      community Earliest we can get legitimate pyrilutamide

      in Research/Science  48 upvotes 2 years ago
      Pyrilutamide, a drug in phase 3 trials in China, potentially becoming available in late 2023 or early 2024; Finasteride being used as a current treatment for hair loss; and the possibility of joining a group buy for black market versions of Pyrilutamide.

      community Clascoterone study going on right now

      in Research/Science  352 upvotes 5 months ago
      A user is participating in a phase 3 trial for Clascoterone, a topical acne medication that may stimulate hair growth, and will share results after 6 months. They will have a section of their hair shaved and marked with a tattoo for the study.

      community HMI-115 update: Chime Biologics and Hope Medicine Enter Manufacturing Agreement to Speed up the Launch of First-in-class Antibody Drug HMI-115 Targeting Endometriosis and Androgenic Alopecia

      in Research/Science  109 upvotes 11 months ago
      Chime Biologics and Hope Medicine are speeding up the launch of a first-in-class antibody drug, HMI-115, for endometriosis and androgenic alopecia. The treatment involves a series of subcutaneous injections, has shown promising results in phase 1, and continues to promote hair regrowth even after the treatment is stopped.

      community Kintor pyrilutamide presentation?

      in Research/Science  12 upvotes 1 year ago
      The conversation is about whether the phase 2 results for pyrilutamide, a potential hair loss treatment, were presented at a dermatology convention and inquiries about the completion of phase 3 trials. Specific treatments mentioned include pyrilutamide.

      community Please stop looking for a natural way to stop your hairloss

      in Chat  247 upvotes 2 years ago
      There is no natural way to stop hair loss; pharmaceuticals like minoxidil, finasteride, and RU58841 are the only effective treatments. Some users report success with minoxidil and microneedling, while others discuss the side effects of finasteride.

      community Second shed, non-stop flaking, itching

      in Treatment  12 upvotes 5 months ago
      The user is experiencing a second hair shedding phase and increased flaking and itching while using minoxidil 5% nightly and microneedling every two weeks, with needle length increasing over time. Other users suggest the hair loss may continue without the use of finasteride.

      community Chances of GT20029 hitting the black market?

      in Treatment  11 upvotes 5 months ago
      The conversation is about the potential availability of GT20029 on the black market and whether users would try it. Participants advise waiting for phase 3 trial results to ensure safety and efficacy.

      community Oral minoxidil is not an option anymore

      in Minoxidil  42 upvotes 5 months ago
      A user can't refill their oral minoxidil prescription due to it being out of stock and is seeking alternative hair loss treatments. Suggestions include finding it at another pharmacy, ordering online, using topical minoxidil orally, and considering finasteride or dutasteride.

      community I’m Feeling so discouraged and depressed - No one wants to prescribe finasteride to me.

      in Finasteride/Dutasteride  68 upvotes 6 months ago
      A user in France is frustrated because three dermatologists refused to prescribe finasteride for their hair loss, suggesting it's not androgenetic alopecia (AGA) and offering expensive vitamin treatments instead. Other users suggest buying hair loss treatments like minoxidil and finasteride from various online pharmacies and considering a gender-affirming care physician for more understanding treatment options.

      community Where is GT20029 already? Grrrr

      in Research/Science  20 upvotes 7 months ago
      The conversation is about frustration over the delay in phase 2 results for a hair loss treatment called GT20029. One user suspects the treatment may have failed.

      community Propecia/Finasteride Where does it come from?

      in Finasteride/Dutasteride  3 upvotes 2 years ago
      The user is taking finasteride 1mg from Blink pharmacy, sourced from Ascend Laboratories, with no noticeable side effects after 5 months. They also use Kirkland foam minoxidil, micro needling, and various supplements for hair treatment.

      community What brand of Dutasteride should I buy?

      in Finasteride/Dutasteride  16 upvotes 1 month ago
      A user asked about the difference between two brands of Dutasteride on Oxford Online Pharmacy. Replies indicated no difference besides the brand name, and one user found Dutasteride more effective than Finasteride.

      community Is this finasteride legitimate

      in Finasteride/Dutasteride  2 upvotes 3 months ago
      A user is concerned about the legitimacy of their finasteride from Simple Online Pharmacy. Another user notes similarities and differences with their own order from Dr. Fox but is unsure about the authenticity.

      community Second Shed recovery Motivation

      in Progress Pictures  146 upvotes 5 months ago
      A user shared their experience with hair recovery after a second shedding phase while using Finasteride. They advise staying consistent with treatment, as it can take 1-2 years or more to see results, and also mention using Ketoconazole but are unsure of its effectiveness.

      community Is there any new drug that looks promising ?

      in Research/Science  25 upvotes 6 months ago
      The conversation discusses GT20029, a drug in Phase II trials that targets androgen receptors with minimal systemic effects, and TDM-105795, a growth stimulant with a different mechanism than minoxidil that may revive papilla stem cells. Both are potential new treatments for hair loss.

      community Further prolactin research....

      in Research/Science  6 upvotes 8 months ago
      HMI 115 did not work as expected for hair regrowth in humans, unlike in macaque monkeys. There is anticipation for further research on prolactin's role in hair loss, with expectations that pharmaceutical companies will likely solve this before universities.

      community Surprisingly thorough study on He-Shou-Wu/Fo Ti

      in Research/Science  14 upvotes 1 year ago
      He Shou Wu (Fo Ti) extract was found to prolong the hair growth phase, inhibit 5-alpha-reductase (like finasteride), reduce androgen receptors, and increase growth factors, potentially outperforming minoxidil in recovering hair follicle size after DHT exposure. Two compounds, emodin and TSG, are identified as responsible for these effects and warrant further investigation.

      community Latanoprost Availability – Canada

      in Treatment  2 upvotes 1 year ago
      Latanoprost for hair loss is available in Canada at Ford's Family Pharmacy in New Brunswick, with up to 0.03% concentration, six times stronger than glaucoma medication Xalatan.

      community Why I still have faith in KX-826

      in Research/Science  54 upvotes 1 month ago
      KX-826 shows promise for hair maintenance at higher doses with minimal side effects, despite failing Phase III trials. The user believes it is more effective than Minoxidil, Finasteride, and RU58841.

      community They've stopped selling this in the UK

      in Ketoconazole  6 upvotes 3 months ago
      Ketoconazole is no longer sold in the UK, and pharmacies have replaced it with non-ketoconazole options. Users are discussing its availability and possible alternatives.

      community Topical Finasteride in India??

      in Finasteride/Dutasteride  6 upvotes 3 months ago
      The post expresses frustration over the unavailability of pure topical finasteride in India despite the developed pharma industry. The user seeks advice on making it at home and its effectiveness.

      community Topical Minoxidil /Fin with tretinoin

      in Minoxidil  1 upvotes 5 months ago
      A dermatologist prescribed a topical solution with 7% minoxidil, 0.1% finasteride, and 0.015% tretinoin from Medrock pharmacy. The user is asking if anyone has tried it and if it contains alcohol.

      community Is Anyone using Latanoprost at all?

      in Product  10 upvotes 6 months ago
      A user discusses using latanoprost, a costly treatment that may extend the hair growth phase and improve hair quality, wondering why it's not more popular. They already use a combination of finasteride and minoxidil and plan to incorporate latanoprost into their routine.

      community Second shed and what I have learned (don't worry!)

      in Minoxidil  45 upvotes 7 months ago
      A 25-year-old experienced significant hair regrowth using 5% minoxidil for 9.5 months despite an initial shed and a second shedding phase lasting 3.5 months. They encourage others to persist with minoxidil treatment through shedding as regrowth can occur.

      community Hope Medicine HMI-115 got 28M$ investment

      in Research/Science  60 upvotes 7 months ago
      Hope Medicine received a $28M investment for HMI-115, a monoclonal antibody in phase II trials for treating androgenetic alopecia. Some users are skeptical about its effectiveness, while others find the investment and trial results encouraging.