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    GlossaryScarring Alopecia (PCA)

    inflammation destroys hair follicles, replacing them with scar tissue

    Scarring Alopecia, also known as cicatricial alopecia, is a group of hair loss disorders where inflammation destroys hair follicles and replaces them with scar tissue, leading to permanent hair loss. This condition can be caused by various factors, including autoimmune diseases, infections, or physical trauma, and often requires a biopsy for accurate diagnosis and targeted treatment.

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      community Can I mix minoxidil with Alpecin Caffeine Liquid?

      in Minoxidil 4 months ago
      A user is considering mixing 5% topical minoxidil with Alpecin Caffeine Liquid to enhance its effect, while also using oral finasteride. They seek feedback on potential efficacy loss and downsides of this mixture.
      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  821 upvotes 5 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community It's over. Hairline has fallen. Millions must shave.

      in Update  467 upvotes 1 year ago
      The conclusion of the conversation is that the user has tried various medications and treatments for hair loss, including minoxidil, finasteride, microneedling, and nizoral shampoo, but has not seen any progress. They have decided to shave their head. Other users suggest options such as hair transplants, RU58841, hair units, and scalp micropigmentation.