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      The story of RU58841/ PSK3841

      community The story of RU58841/ PSK3841

      in Research  622 upvotes 6 months ago
      RU58841, a potential hair loss treatment, was not commercialized due to marketability issues and lack of long-term safety data. Concerns about its formulation and delivery methods further complicate its use.

      community Do we have to be junkies? That's funny

      in Research/Science  13 upvotes 7 months ago
      The conversation discusses using finasteride, dutasteride, minoxidil, cialis, and metformin to protect hair and health. Some users caution against self-prescribing these drugs due to potential risks and complications.

      community Expectations control for SCUBE3

      in Research/Science  22 upvotes 11 months ago
      SCUBE3, a protein linked to hair growth in moles, was discovered over 25 years ago and is being developed by Amplifica for potential hair loss treatment. Concerns exist about SCUBE3's association with cancer, as it is a protein that promotes cell growth, which could potentially trigger cancer development if used for hair growth therapy.

      community Has anyone else seen this encouraging verteporfin case study?

      in Progress Pictures  37 upvotes 1 year ago
      The conversation discusses the potential use of verteporfin for hair loss treatment, with one user mentioning their surgeon's interest in trying it and another noting its research status and clinical use as a YAP inhibitor. Some users debate the market size, availability of generics, and the optimism in the hair loss community regarding new treatments.

      community why hair restoration has not been progressed for last 20 years?

      in Chat  33 upvotes 1 year ago
      The conversation discusses the lack of significant advancements in hair loss treatments beyond finasteride and minoxidil, questioning if hair restoration technology has reached a dead end. Hair transplant technology has improved, but new medications face challenges with market entry, cost, accessibility, and long-term effectiveness.

      community I hate it when people write off your hairloss info because “you’re not a doctor.”

      in Treatment  76 upvotes 1 year ago
      A user shared their frustration about their cousin's refusal to take their advice on using finasteride for aggressive hair loss, despite the cousin's desperation and current use of minoxidil and consideration of PRP injections. The user, who has done extensive research, suggested the cousin needs a 5ar inhibitor, but the cousin dismisses the advice because the user isn't a doctor.

      community could Tretinoin alone cause regrowth?

      in Treatment  7 upvotes 1 year ago
      The user has maintained their hairline with finasteride for 5 years and saw no results from minoxidil. They are inquiring if tretinoin alone can cause hair regrowth.

      community Overwhelming amount of anti-androgens

      in Female 1 year ago
      The conversation discusses the effectiveness of anti-androgens for hair loss, with a preference for topical treatments like RU58841 over oral options due to better scalp concentration and fewer side effects. Topical finasteride at 0.1% may provide some results, especially when combined with a topical androgen receptor antagonist like RU58841.

      community Actifollic Will sell pyrilutamide😱

      in Treatment  18 upvotes 2 years ago
      Actifollic selling Pyrilutamide as a treatment for hair loss, with people debating its efficacy compared to Minoxidil and Finasteride in combination with RU58841.

      community BREEZULA COVID UPDATE: Filing for Special Protocol Assessment with FDA

      in Research/Science  63 upvotes 4 years ago
      The conversation discusses the progress of Clascoterone (Breezula) for hair loss treatment, noting that COVID-19 delayed female trials by three months but Phase III trials for males are proceeding with a Special Protocol Assessment filed with the FDA. Users express hope for Breezula as an alternative to existing treatments like finasteride and minoxidil, despite concerns about its potential high cost.

      community What the hell does it mean by “do not apply to front of scalp”

      in Minoxidil  24 upvotes 3 months ago
      Minoxidil can be applied to the entire scalp, including the hairline, despite labels suggesting otherwise due to lack of specific testing. For best results in treating hair loss, combining minoxidil with finasteride is recommended, as finasteride addresses the underlying cause of male pattern baldness.

      community Sharing my (relatively short) Success Story

      in Progress Pictures  77 upvotes 1 year ago
      A user named "paulsac11" shares their success story of treating hair loss. They started with topical minoxidil, then switched to oral minoxidil and dutasteride. They also used a shampoo and conditioner from Keeps. After eight months of treatment, they have seen significant improvement in their hairline.

      community Scalp Micropigmentation while having hair

      in Treatment  6 upvotes 2 years ago
      User discusses scalp micropigmentation for denser hair appearance and its benefits compared to lifelong treatments. Special ink is used, which can fade and blur over time but can be topped up.

      community Is PP405 formula available in grey market?

      in Treatment  14 upvotes 2 weeks ago
      The conversation is about the availability of the PP405 formula for hair loss treatment, with mentions of finasteride and its side effects. Users discuss the potential of obtaining the formula through unofficial channels and the challenges related to its genetic sequence and delivery method.

      community 3 Years of Xmas comparison (11 Months, Oral Min/Fin)

      in Progress Pictures  1217 upvotes 1 month ago
      The user experienced significant hair regrowth using a single pill containing 2.5mg minoxidil and 1mg finasteride over 11 months, with noticeable improvements starting around month 8. They reported minor side effects initially but none ongoing, and they have not undergone a hair transplant.

      community The Cure isn't 5 years away; it's already here.

      in Research/Science  998 upvotes 2 months ago
      PP405 is a new topical treatment for hair loss, showing promise in trials but still requires finasteride for maintenance. There is skepticism about its effectiveness and safety, with concerns about needing finasteride to maintain results.