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      community Hair theory Scar tissue and Verteporfin

      in Chat  25 upvotes 3 months ago
      A user suggests that deeper microneedling with Verteporfin injections might help regrow hair in areas with scar tissue, alongside a DHT blocker. Another user explains that hair loss might be due to reduced Wnt/β-Catenin signaling and suggests that treatments like Minoxidil, Finasteride, and microneedling could potentially reverse it.

      community Has anyone ever had success with just micro-needling?

      in Microneedling  20 upvotes 5 months ago
      People are discussing if microneedling alone can improve hair loss without using treatments like minoxidil, finasteride, or RU58841. Some users report moderate success with microneedling and natural remedies, but most suggest that results are better when combined with medical treatments.

      community Keratin microspheres - breakthrough

      in Research/Science  13 upvotes 6 months ago
      A gel of keratin microspheres promotes hair follicle growth, showing similar effectiveness to minoxidil in mice. The treatment activates hair growth pathways and reduces inflammation, with potential applications in drug delivery for hair-related disorders.

      community Losing gains from 7 months of oral min, fin, dut.

      in Update  66 upvotes 10 months ago
      A user reported losing hair after 7 months of using oral minoxidil, finasteride, and dutasteride, but others reassured that this is likely just a shedding phase where old hairs fall out to make way for new growth. Some users experience sheds every 7-8 months and suggest staying consistent with treatment.

      community The MPB itch aka DHT itch is very real.

      in Chat  9 upvotes 1 year ago
      Hair loss itch is caused by DHT attacking follicles and stimulating nerves. Finasteride users who respond well don't experience this itch.

      community Pyrilutamide update: three months

      in Update  32 upvotes 1 year ago
      A user's 3-month experience with pyrilutamide to reduce hair shedding, and how it may not be strong enough to stop the thinning of their hairline. Other users mentioned the effectiveness of minoxidil and finasteride for treating hair loss.

      community Dr Kyle Gillett on topical Dutasteride

      in Finasteride/Dutasteride  56 upvotes 1 year ago
      The potential effectiveness of topical dutasteride, as well as other hair loss treatments such as finasteride, RU58841, minoxidil, and various vitamins. Experiences from users who have used these treatments were shared.

      community Last resort attempt. Studies suggest that finasteride topically actually inhibits up to 52% scalp dht which is smiles to dut 0.5mg daily. This solution contains: fin, min, melatonin and progesterone. Trial started today.

      in Research/Science  9 upvotes 2 years ago
      The conversation discusses a last-resort hair loss treatment combining topical finasteride, minoxidil, melatonin, and progesterone, with claims that topical finasteride can inhibit up to 52% of scalp DHT. One reply clarifies that progesterone is not an anti-androgen but has anti-androgenic properties because it competes with androgens for receptors.

      community Stopped minoxidil for a year after a year of using it. Starting again.

      in Minoxidil  158 upvotes 2 years ago
      ? This post by PastelDeUva discusses their experience with Minoxidil and Finasteride for hair loss treatments, which they stopped using for a year before resuming due to family's negative opinion. After restarting, they posted photos of the progression/regression of their hairline and are now planning on adding finasteride and dermarolling in order to get good results.

      community A doctor says to NEVER massage Minoxidil

      in Minoxidil  11 upvotes 3 years ago
      A user is concerned about the best method to apply Minoxidil for hair loss, noting conflicting advice from doctors. Another user mentions that not massaging the liquid can cause it to drip, suggesting slight spreading with fingers.

      community This serum outperformed Minoxidil in a recent study. Please debunk

       23 upvotes 4 years ago
      A topical solution called "Multi-Peptide Serum for Hair Density" by The Ordinary Company, which contains several ingredients that are used in alternatives to Minoxidil and was found to have better results than 5% Minoxidil in a study. People who have tried it shared their experiences with the serum as well.

      community Natural Remedies: Polyphenols and Hair Loss

       20 upvotes 5 years ago
      Natural remedies to treat hair loss, such as polyphenols, apple peel extract, grape seed extract, green tea extract, peppermint oil, pumpkin seed oil, apigenin, Ginkgo biloba, red clover extract, olive leaf extract, Ecklonia Cava and Grateloupia elliptica. In addition, terpenes, carotenoids, and tocopherols were discussed as potential treatments.

      community If Breezula stops further hair loss without side effects it's basically a cure

       19 upvotes 5 years ago
      The conversation discusses whether Breezula could be considered a cure for hair loss if it stops hair loss without side effects, acknowledging that it's not very effective for regrowing hair. Some believe a combination of hair transplants and topical treatments like Breezula could be effective, while others doubt its efficacy and the practicality of topicals as a cure.
      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 1 month ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Topical finasteride now the safest possible path?

      in Finasteride/Dutasteride  50 upvotes 2 months ago
      Topical finasteride is considered a safer option for hair regrowth with fewer systemic side effects compared to oral finasteride. Some users report similar efficacy and side effects between topical and oral treatments, while others prefer topical due to reduced systemic exposure.

      community Verteporfin and Microneedling

      in Treatments 3 months ago
      Clinical studies by Dr. Barghouthi and Dr. Bloxham indicate that Verteporfin, when used with FUE and FUT hair transplantation methods, shows promise in hair follicle regeneration and minimal scarring due to its ability to inhibit Yes-associated protein (YAP). Microneedling at depths of 3-3.5mm, combined with Verteporfin, could potentially reactivate dormant follicles, although the optimal dosage and application method are still under investigation. Concerns remain about the DHT sensitivity of regenerated follicles, highlighting the need for further research to optimize trauma levels and Verteporfin concentrations to achieve effective and scar-free hair regeneration.

      community Fats on your Head to Stop Hair Loss?

      in Research/Science  143 upvotes 7 months ago
      The conversation discusses the potential of long-chain unsaturated fatty acids, like oleic and linoleic acid, as an additional treatment for hair loss, which may inhibit the enzyme responsible for converting testosterone to DHT and promote hair growth. Users humorously suggest using oils topically and discuss other hair loss treatments, but the main focus is on the science behind fatty acids and their role in hair health.

      community Approximation of Scalp DHT Suppression Between 0.05 mg to 2.5 mg

      in Research/Science  63 upvotes 8 months ago
      The conversation discusses the effectiveness of various doses of Dutasteride in reducing scalp DHT and its impact on hair count. Users shared personal experiences with hair loss treatments, including Dutasteride, Finasteride, and Minoxidil, with one reporting significant hair loss reduction using a combination of oral Dutasteride and topical Minoxidil and Finasteride.