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GlossarySystemic Medications (Oral Drugs)

drugs that affect the entire body via bloodstream

Systemic medications are drugs that work throughout the entire body rather than targeting a specific area. They are often taken orally or injected, allowing the active ingredients to enter the bloodstream and reach various tissues and organs. This type of treatment is commonly used for conditions that affect multiple parts of the body, such as autoimmune diseases or widespread infections.

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community 18M 10 months on anti-androgens and oral min

in Progress Pictures 50 upvotes 10 months ago

An 18-year-old male used anti-androgens and oral Minoxidil for 10 months to treat hair loss. He initially used 1mg Finasteride and 5% topical Minoxidil for 5 months, then switched to Dutasteride for 4.5 months and inconsistently used 5mg oral Minoxidil for 2 months due to availability issues.

community Effectiveness of Dutasteride opinions

in Finasteride/Dutasteride 11 upvotes 7 months ago

The conversation discusses the effectiveness of Dutasteride for hair loss, with some users reporting it works better than Finasteride and sharing positive experiences, while others are skeptical due to negative anecdotes. Specific treatments mentioned include Dutasteride and Finasteride.

community Homemade topical spironolactone

in Research/Science 26 upvotes 2 years ago

The potential effectiveness of homemade topical spironolactone in treating hair loss, with studies suggesting it is more effective than finasteride and even minoxidil when used as monotherapy. The conversation also mentions that other anti-androgens are being developed which may soon hit the market.

community Finasteride progress 0.25-0.5mg 11 months

in Progress Pictures 378 upvotes 2 months ago

User shared progress pictures showing significant hair improvement after using finasteride (0.25-0.5mg daily) for 11 months. Other treatments like microneedling, ketoconazole, and scalp massage were mentioned but not used consistently.

community Anecdotal, but: Adding RU58841 has stopped my Dutasteride shed

in Finasteride/Dutasteride 21 upvotes 10 months ago

Adding RU58841 to Dutasteride treatment helped reduce hair shedding significantly for several users. Some reported no change with RU58841, while others experienced a dramatic decrease in shedding and increased hair density.

community to all people who cannot tolerate anti androgens (loe dose topical fin, pyrilutamide, CB) i am getting desperate, looking for a solution

in Research/Science 13 upvotes 1 year ago

The user tried Minoxidil without success, and Finasteride worked but caused sexual side effects even at a very low dose. They are seeking alternative treatments for hair loss as they cannot tolerate anti-androgens and are also in therapy for mental health.

community 6-months on Hims topical minoxidal and finasteride combination, and microneedling once every week or two. The before pic was taken with the front iphone camera so is lower resolution which makes a comparison hard, but perhaps seeing some minor gains in individual hairs thickening.

in Progress Pictures 2 years ago

Using a combination of topical minoxidil and finasteride, plus microneedling, to treat hair loss; the progress made by the original poster over 6 months; the potential for further results with longer use; and the possibility of seeking alternatives such as a hair transplant or system.

community I think I might have cured my hairloss

16 upvotes 10 years ago

The user experienced severe dandruff and hair loss, trying various treatments including oils, vitamins, and minoxidil. They found success by simply dampening their scalp with water twice a day, which improved their hair's appearance and eliminated psoriasis.

community Six months of only Dermarolling

in Progress Pictures 157 upvotes 1 year ago

User tried dermarolling for hair loss and shared progress pictures. Some suggest adding finasteride and minoxidil, while others debate effectiveness and frequency of dermarolling.

community Kintor has announced the results for their human Phase I trials of GT20029

in Research/Science 256 upvotes 1 year ago

The conversation discusses the potential of a new hair loss treatment, GT20029, which may prevent hair loss by destroying androgen receptors on the scalp. Users express hope for the treatment's success and speculate on its usage routine, effectiveness, and possible side effects.

community Anageninc no longer sell KX-826 (Pyrilutamide) due to receiving a cease and desist letter from Kintor :(

in Update 18 upvotes 1 year ago

Hair loss treatments discussed include Minoxidil, Finasteride, and RU58841. Anageninc stopped selling KX-826 (Pyrilutamide) due to a cease and desist letter from Kintor, but this may indicate promising study results and a potential 2024 release.

community 3 months of 1 mg finasteride and 5 mg minoxidil (oral)

in Progress Pictures 2 years ago

A user's progress with hair regrowth after 3 months of using 1 mg finasteride and 5 mg minoxidil orally, despite some skepticism from other users. The user reports having low blood pressure and feeling fatigued as side effects, but others suggest switching to topical minoxidil for better results with less risk.

community Approximation of Scalp DHT Suppression Between 0.05 mg to 2.5 mg

in Research/Science 63 upvotes 8 months ago

The conversation discusses the effectiveness of various doses of Dutasteride in reducing scalp DHT and its impact on hair count. Users shared personal experiences with hair loss treatments, including Dutasteride, Finasteride, and Minoxidil, with one reporting significant hair loss reduction using a combination of oral Dutasteride and topical Minoxidil and Finasteride.

community FOL005 claims it's better than Finasteride and Minoxidil.

in Technology 185 upvotes 2 months ago

FOL-005 claims to be more effective than Minoxidil and Finasteride but lacks anti-DHT properties, leading to potential reduced efficacy over time. Concerns are raised about misleading marketing and the safety of alternative treatments like Pyrilutamide and Clascoterone.

community 17 years fighting hair loss. My story

in Progress Pictures 78 upvotes 1 year ago

ExistingAd915's 17 year journey of fighting hair loss, which included the use of finasteride, minoxidil, and dutasteride. He has seen positive results from his treatments, with an overall improvement in hair density.

community Proof that finasteride messes with neurosteroids

in Research/Science 230 upvotes 2 months ago

Finasteride can impact neurosteroids, potentially causing depression and other side effects in some users. Despite these concerns, many continue using it for hair loss, with some switching to topical applications to mitigate side effects.

community Kinda crazy you don’t realize how much minoxidil does for you until you stop and see the loss

in Minoxidil 89 upvotes 6 months ago

People shared experiences of hair loss after stopping minoxidil, despite also using finasteride. Some tried microneedling or hair transplants, but stopping minoxidil often led to significant hairline recession.

community Oral Minoxidil Users In A Nutshell

in Satire 1214 upvotes 2 years ago

This conversation is about hair loss treatments, specifically oral minoxidil and finasteride. Users discussed the potential side effects of using these drugs, as well as their experiences with them.

community Cheap and Easy Hair Loss Treatment Drugs Megathread

in Product 13 upvotes 1 month ago

The conversation discusses affordable hair loss treatments, including oral dutasteride, oral and topical minoxidil, oral finasteride, 2% ketoconazole shampoo, and topical finasteride/minoxidil mixtures. Users share methods to obtain these drugs cheaply and legally.

community Why Viagra promotes hair growth like oral minoxidil

in Minoxidil 84 upvotes 2 years ago

How oral minoxidil and topical sildenafil (similar to Viagra) are used for hair growth by increasing blood flow to the scalp, and potential side effects of combining these treatments with other drugs.

community 14 Months on nuclear stack (0,5 DUT and 15mg oral Minox and no regrowth. Aga is impossible to beat

in Progress Pictures 9 months ago

The user has been on a hair loss treatment for 14 months using dutasteride and oral minoxidil without seeing regrowth and is considering adding more drugs due to the psychological impact of hair loss. However, replies suggest the user may not actually be experiencing noticeable hair loss.

community New topical Dutasteride from Moogene will have 20 times better scalp absorption than oral Dutasteride. And much lower system absorption.

in Finasteride/Dutasteride 177 upvotes 2 years ago

A new topical Dutasteride with 20 times better scalp absorption being developed and tested for release in 2023; use of existing drugs, such as Minoxidil and finasteride; and mesotherapy as an alternative hair loss treatment.

community Updates about KX-826 & GT20029

in Research/Science 17 upvotes 1 year ago

The conversation discusses potential advancements in two hair loss drugs, KX-826 and GT20029, and the interest in whether transitioning from oral finasteride to these drugs would maintain hair growth. One reply expresses skepticism about the compounds' representation.

community DUT Risk profile for having kids?

in Finasteride/Dutasteride 5 upvotes 1 year ago

The user has been using a hair loss treatment including oral Minoxidil, topical Minoxidil with Tretinoin and Finasteride, and is considering adding Dutasteride but is concerned about the potential side effects and risks regarding fertility. A reply suggests that having children while on these medications should be fine, advising to avoid letting the partner come into contact with the drugs.

community 2020 Hair and Scalp Treatments: A Clinical Guide (in Depth 350 Page Guide)

in Treatment 63 upvotes 4 years ago

Treatments for hair loss, including topical immunotherapy, regenerative treatments, laser and light-based therapies, oral supplements, intralesional steroids, and new drugs like finasteride and minoxidil.

community Hair progress over 7 years (Oral fin 1mg + oral min 2.5mg + topical min 5% + micro-needling)

in Progress Pictures 193 upvotes 5 months ago

The user shared a 7-year hair progress journey, starting with occasional minoxidil use and later including a finasteride prescription, online prescriptions, and microneedling. Significant hair growth was achieved, but side effects led to a reduction in medication dosage.

community Puffy eyes / fluid retention on Oral Minoxidil? Add an ACEi or ARB! NOT MEDICAL ADVICE

in Minoxidil 8 upvotes 2 years ago

Oral Minoxidil can cause puffy eyes and fluid retention. Adding an ACE inhibitor or ARB, like Telmisartan, may help mitigate these side effects.

community 6 Months on Oral Fin/Oral Min, I’m 22. I also use a LOT more product on my hair

in Progress Pictures 104 upvotes 4 months ago

GriffinLiftin experienced significant hair regrowth after 6 months using oral finasteride and minoxidil, along with hair care products like leave-in conditioner, curl-cream, and olive oil. They started treatment early due to a family history of balding and are pleased with the life-changing results.

community All Drugs in Clinical Trials in 2023

in Research/Science 70 upvotes 1 year ago

12 companies having drugs or therapies in clinical trials during 2023, with various molecules and phases of trial; the probability that some may fail; and progress being made in the field.

community Oral dutasteride vs topical efficacy

in Finasteride/Dutasteride 60 upvotes 4 months ago

The user switched from topical minoxidil/dutasteride to oral dutasteride, resulting in hair loss. They resumed topical treatment without regrowth and are considering switching to finasteride due to poor results with oral dutasteride.