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3aHSD enzyme's role in hair loss and a crowdfund for research. Goal: explore new treatments, study RU58841, and develop natural topical product.

The conversation is about using natural DHT blockers like pumpkin seed oil and saw palmetto extract for hair loss. The user has been using minoxidil, derma rolling, vitamin D, and biotin but is considering finasteride next.

No natural way to stop hair loss, pharmaceuticals only option. Users discuss Minoxidil, Finasteride, natural remedies, and healthy scalp importance.

The post and conversation are about a user's 10-month update on natural hair loss treatment, with mixed feedback on its effectiveness. Some suggest using finasteride and minoxidil for better results.

High cost of studying 3α-Hydroxysteroid dehydrogenase in hair loss led to suggestions of crowdfunding for research. Users discussed using Procyanidin B2/melatonin topical treatment and tracking funds with blockchain.

Finasteride and dutasteride are essential for stopping hair loss, while natural remedies are ineffective. Minoxidil can be added if needed, but blocking DHT is crucial.

The conversation is about Jordan Peterson allegedly getting a hair transplant, with various users mocking his way of speaking and debating the ethics of him potentially hiding the procedure. Some users discuss the natural look of the transplant and the implications of getting one at an older age.

The post discusses speeding up verteporfin trials for hair loss treatment. The original poster, involved in the trials, requests help in crowdsourcing doctor emails to spread awareness and gather more support for the trials.

The user shared their positive hair regrowth experience using saw palmetto tablets, 5% minoxidil spray, and a Derma Pen. The conversation debates the effectiveness of saw palmetto versus finasteride, with some advocating for natural treatments and others emphasizing the proven results of finasteride and minoxidil, often in combination with microneedling.

The conversation discusses RU58841, a compound for hair loss treatment, which was found to be effective in a 6-month trial but was not pursued due to financial issues or marketability concerns, not safety. Some users are considering crowdfunding to release the research data, while others discuss personal experiences and safety concerns with RU58841.

The user shared progress pictures showing hair improvement after using Minoxidil for over a year and Finasteride for 8 months. They use a topical spray of Minoxidil twice a day and have seen positive changes in hair density and appearance.

A 28-year-old male reported significant hair regrowth after 5 weeks using a regime including Minoxidil, Ketozolin shampoo, microneedling, hyaluronic acid, saw palmetto, pumpkin seed, MSM, frankincense, zinc, multivitamins, and vitamin D. He also noted improvements in digestion, dry eyes, and skin health, and observed beard growth from microneedling.

Whether topical caffeine can be as effective for hair growth as minoxidil and finasteride, with various replies discussing the efficacy of these treatments and criticism of Dr. Huberman's research methods.

A user who has been shaving his head for 15 years looking for potential treatments to regrow hair; the replies range from advice to try out medications such as finasteride and minoxidil, to suggestions of changing up his look with facial hair or hobbies.

The user is using RU58841, finasteride, dutasteride, and minoxidil to slow down aggressive hair loss but is still experiencing hair shedding due to high testosterone levels. They plan to use ostarine to lower testosterone and prevent hair loss while maintaining muscle mass, and will continue using the other treatments.

TWIST-1 gene's role in hair loss and potential as a treatment target. Inhibiting TWIST-1 may prolong hair growth and reduce hair follicle sensitivity to DHT.

The conversation discusses an interview with Dr. Tsuji about hair follicle stem cell multiplication and the financial challenges of starting human clinical trials. It also mentions the need for funding to secure a patent for a protein that promotes hair growth.

Stopping finasteride often restores sexual function, with many experiencing improved libido and erections. Some users switch to minoxidil or topical finasteride to manage side effects while maintaining hair health.

Dutasteride users report mixed experiences, with some experiencing significant hair shedding and others seeing improvement after initial shedding. Many users switch from finasteride to dutasteride, hoping for better results, but reactions vary widely, with some facing allergies or worsening hair loss.

Significant hair improvement was reported after 18 months of using 1mg dutasteride and 2.5-5mg oral minoxidil daily for diffuse unpatterned alopecia. The discussion includes praise, skepticism about authenticity, and concerns about side effects.

The conversation is about hair loss treatments, specifically a stack including topical Ashwagandha, Copper Peptide, Gotu Kola, Ketoconazole, and PDA. One user found Topical and Sub-Q GHK-CU effective.

The user experienced significant hair improvement after one year using topical finasteride and minoxidil, combined with a hair transplant at the front. They switched from oral to topical finasteride due to side effects and are satisfied with the results, especially at the temples.

The conversation is about hair loss and the use of finasteride as a treatment. Some users share their positive experiences with finasteride, while others mention side effects they have experienced.

A user's nine-month journey of hair growth with treatments including finasteride, minoxidil, and nizoral; some participants thought the user had a hair transplant while others disagreed.

User TopBack56 and friends tried pyrilutamide (KX-826) for hair loss without experiencing negative side effects. They observed fine vellus hairs but no thick hair growth yet, and plan to add GT20029 to their regime after safety trials.

The post and conversation are about the role of the enzyme 3alpha-hydroxysteroid reductase in hair loss and the potential of compounds like procyanidin B2 and sulforaphane to boost its activity for hair regrowth. Further research is needed to develop effective treatments based on this theory.

The conversation discusses the side effects of finasteride, including low libido and erectile dysfunction, and the possibility of these effects being permanent, known as post-finasteride syndrome (PFS). Some users report personal experiences with PFS and debate whether the condition is real, with varying opinions on the reversibility of side effects and the role of individual biology.

Accepting hair loss and not taking drastic measures like shaving your head if you are only mildly balding, and encouraging people to fight it with treatments such as finasteride, minoxidil, nizoral and microneedling. Additionally, it discusses the importance of being realistic when trying to restore hair and addressing the misconception that one must look a certain way in order to be attractive.

Topical minoxidil may cause skin aging effects like wrinkles and dark circles, possibly due to its alcohol content, while oral finasteride is reported to make users look younger. Switching to oral minoxidil or using moisturizers might help reduce these skin issues.

Checking vitamin and hormone levels is important for addressing hair loss, as deficiencies in vitamin D, zinc, and iron can affect hair growth. Treatments like finasteride, minoxidil, and vitamin supplements are used, but addressing deficiencies is crucial for effectiveness.