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      community PP405 - hair stem cell stimulation

      in Research/Science  51 upvotes 6 months ago
      PP405, a topical LDH inhibitor, has shown to stimulate hair follicle stem cell proliferation in humans with moderate hair loss. They are advancing to more detailed trials this year.

      community 1yr of treatment 40yr old min/dut/ru/needling

      in Progress Pictures  353 upvotes 6 months ago
      A 40-year-old used minoxidil, dutasteride, RU58841, and microneedling for one year, resulting in noticeable hair regrowth despite initial shedding. They believe having more hair is beneficial for dating at their age and also recommend staying fit, eating well, and sleeping over 8 hours.

      community Shaved it off and already grateful! I have a question for those here.

      in Shaved/buzzed  42 upvotes 6 months ago
      LazyJam shaved their head after not seeing significant results from using finasteride and microneedling for hair loss, feeling more self-acceptance and saving money. Others in the conversation discuss their own reasons for continuing hair loss treatments, such as personal appearance, self-esteem, and not wanting to shave regularly.

      community [5 year progress] My gains and experience

      in Progress Pictures  356 upvotes 6 months ago
      A user shared a 5-year hair loss treatment progress, using 1mg oral finasteride daily and 5% minoxidil liquid twice per day, with significant improvement and no side effects. They noticed more hair coverage around the 6-7 month mark and have experienced annual shedding but remained consistent with their routine.

      community Anyone have better luck with Dutasteride over Finasteride?

      in Finasteride/Dutasteride  8 upvotes 6 months ago
      The conversation is about someone who has tried various dosages of finasteride for hair loss without success and is considering switching to dutasteride, which reduces more DHT. They are asking if others have had issues with finasteride but found dutasteride to be more effective without problems.

      community Will minoxidil not work if there’s too much DHT present in the scalp?

      in Minoxidil  5 upvotes 7 months ago
      The user has been using topical finasteride and minoxidil for five months with little progress and is considering oral dutasteride to lower DHT levels, questioning if minoxidil is more effective with reduced DHT. They also use microneedling and tretinoin in their treatment routine.

      community Min + fin eod + keto for 7 months

      in Is this regrowth?  42 upvotes 7 months ago
      The conversation is about someone using minoxidil and finasteride for 7 months to treat hair loss, asking if they've made progress and if they can expect more regrowth. Another person asked if the minoxidil was topical or oral and how often it was applied.

      community Why use Finasteride instead of Dutasteride?

      in Finasteride/Dutasteride  39 upvotes 7 months ago
      People are discussing why some choose finasteride over dutasteride for hair loss, noting that while dutasteride is more effective, it's also more expensive, less researched, and potentially has more side effects. Some users shared personal experiences with side effects from both drugs, and others mentioned that finasteride is FDA approved for hair loss, while dutasteride is not, except in Japan.

      community Verteporfin Update with Dr Blake Bloxham

      in Research/Science  24 upvotes 8 months ago
      The conversation discusses Dr. Blake Bloxham's experiment with Verteporfin for hair loss, with one person suggesting more doctors should try it as it seems beneficial. Another comment notes that results at 4-5 months were not very impressive.

      community New treatment? Minox + Bimatoprost

      in Treatment  6 upvotes 9 months ago
      A user discussed a new hair loss treatment combining 5% Minoxidil with Bimatoprost 0.3mg/ml, applied once daily. They referenced a study suggesting Bimatoprost may be more effective than Minoxidil.

      community 22M | 18 Weeks Progress | Very rapid and aggressive Hairloss since 17 and only learned about Min, Fin, etc. a few months ago | Words can't describe how happy I am with these results and the gains keep coming.

      in Progress Pictures  90 upvotes 9 months ago
      A 22-year-old man has seen significant improvement in his hair loss after 18 weeks using Minoxidil and Finasteride, starting treatment after rapid hair loss since age 17. He applies Minoxidil directly after an unspecified procedure, believing it's more effective and appreciates the sterilizing effect of the ethanol in it.

      community Thoughts on Hims Fin+Min all in one chews

      in Finasteride/Dutasteride  197 upvotes 10 months ago
      Users discussed the convenience and effectiveness of Hims Fin+Min chewable tablets for hair loss. Some believe it's overpriced compared to traditional oral finasteride and minoxidil, while others find it more convenient and potentially more effective.

      community I wish I'd kept on treatment 4 years earlier...

      in Chat  27 upvotes 10 months ago
      The user regrets not continuing hair loss treatment with finasteride earlier and plans to restart it along with minoxidil. Another user suggests trying dutasteride and oral minoxidil as a more effective treatment.

      community Phase 3 of pyrilutamide (kx-836) analysis of the efficacy

      in Research/Science  12 upvotes 10 months ago
      The conversation discusses the less impressive results of Pyrilutamide (kx-836) in phase 3 compared to phase 2, with a suggestion that a longer study might show more significant results. One user reports personal success with Pyrilutamide, experiencing no further hair loss and gradual regrowth.

      community Results 2,5 month on the big 4??

      in Progress Pictures  6 upvotes 10 months ago
      The user has been battling hair loss for 1.5 years, using finasteride and minoxidil inconsistently. In September, they started a more aggressive treatment including Dutasteride, keto, Minox, and a 2mm dermaroller, and after 2.5 months, they are seeking opinions on their progress.

      community Is DUT better or worse than FIN?

      in Finasteride/Dutasteride  62 upvotes 11 months ago
      The conversation discusses the effectiveness of Dutasteride (DUT) and Finasteride (FIN) for hair loss. Users share varied experiences, with some finding DUT more effective and others experiencing side effects or no change, highlighting that individual responses can vary.

      community Finasteride/minoxidil and hair transplant results

      in Progress Pictures  21 upvotes 11 months ago
      The user discussed their hair loss treatment which includes finasteride, minoxidil, hair transplant, biotin, zinc, vitamin D pills, and Nizoral ketoconazole 1% shampoo. They mentioned they are 5 months into the treatment and expect more growth.

      community Topical finasteride might be a lie

      in Research/Science 11 months ago
      The conversation discusses doubts about the effectiveness of topical finasteride for hair loss, suggesting that DHT could be produced elsewhere in the body and affect the scalp. It proposes that androgen receptor antagonists like spironolactone and clascoterone might be more effective as they could prevent this potential bypass mechanism.

      community Trans: Do I need to use Finnasteride?

      in Transgender 11 months ago
      A transgender individual is starting spironolactone and estradiol for hormone replacement therapy (HRT) and is considering adding finasteride to help with hair loss. They are also planning to use minoxidil and microneedle, but are unsure if they need to use another anti-androgen or more aggressive treatments. A respondent advises against using pyri and suggests waiting to see if the HRT alone is sufficient before becoming dependent on minoxidil.

      community Frequency/strength of topical minoxidil application

      in Research/Science  13 upvotes 11 months ago
      The conversation discusses the effectiveness of Minoxidil (Min) for hair loss treatment. It concludes that applying a 5% solution once daily is sufficient, and applying it twice daily doesn't provide much more benefit. However, if a higher concentration is beneficial, it can be achieved by more frequent application.

      community Optimal dose for topical Melatonin

      in Treatment  6 upvotes 1 year ago
      The conversation is about finding the optimal concentration of topical melatonin for hair loss treatment. The user is considering making their own solution and is unsure whether a higher concentration is more effective for deactivating prolactin receptors.

      community I’ve read multiple times that Fin increases hair quality… NOT for me!

      in Treatment  97 upvotes 1 year ago
      A user has been on finasteride for 6 months and feels their hair quality has worsened, experiencing more hair loss and scalp irritation. They are considering seeing a dermatologist, while others suggest the issue might be unrelated to finasteride, possibly due to deficiencies or other conditions.