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      community KX-826: Long-Term Safety Results are out!

      in Research/Science  158 upvotes 1 month ago
      KX-826 initially improves hair growth but declines after 24 weeks, with mild itching as a side effect. Combining it with minoxidil and finasteride may improve results, but long-term effectiveness is uncertain.

      community How to Keep Your Hair on Steroids

      in Treatment  16 upvotes 2 months ago
      To minimize hair loss while using steroids, use finasteride or dutasteride and apply topical anti-androgens like RU58841. Avoid high doses of hair-toxic steroids; prefer testosterone, nandrolone, and boldenone.

      community What’s the most effective way to beat Serb Derm?

      in Treatment  7 upvotes 2 months ago
      OP struggles with scalp flakes causing hair loss and has tried Selsun Blue, Ketoconazole, and ZPT Shampoo without success. Suggestions include using salicylic acid shampoo, shaving the head, using Nizoral, and combining treatments like Minoxidil and finasteride.

      community For all those worried about a minoxidil break

      in Minoxidil  342 upvotes 3 months ago
      Stopping minoxidil can lead to significant hair loss, but resuming it along with finasteride can help regain lost hair over time. Consistency is key for maintaining hair health and regrowth.

      community To everyone who cant use FIN and doesnt want to use RU

      in Treatment  33 upvotes 3 months ago
      A new hair loss treatment, KX-826, is being discussed as a stronger and safer alternative to RU58841 and finasteride. Opinions are mixed, with some users skeptical about its effectiveness and others considering it as part of their regimen.
      The story of RU58841/ PSK3841

      community The story of RU58841/ PSK3841

      in Research  622 upvotes 3 months ago
      RU58841, a potential hair loss treatment, was not commercialized due to marketability issues and lack of long-term safety data. Concerns about its formulation and delivery methods further complicate its use.

      community Received Kintor’s KX-826 Today

      in Product  84 upvotes 3 months ago
      A user received Kintor’s KX-826/Pyrilutamide and shared initial impressions, noting concerns about the product's labeling and marketing. Other users discussed the legitimacy of the product, its effectiveness, and compared it to other treatments like Minoxidil and Finasteride.

      community Why is it "not right" to start off with Dutasteride?

      in Finasteride/Dutasteride  60 upvotes 4 months ago
      The conversation discusses whether it's better to start hair loss treatment with finasteride or dutasteride. Opinions vary, but many suggest starting with finasteride due to its shorter half-life and easier management of side effects, while others argue dutasteride is more effective and has fewer side effects.

      community Gyno & testoterone level

      in Finasteride  282 upvotes 5 months ago
      Switching from finasteride to dutasteride and back to finasteride led to gynecomastia and fatigue, likely due to hormonal imbalances. Suggested treatments include Tamoxifen, Raloxifene, or low-dose Anastrozole, with a recommendation to test testosterone and estradiol levels.

      community blood DHT levels shot up after doubling dutasteride dosage

      in Finasteride/Dutasteride  20 upvotes 6 months ago
      A user increased their dutasteride dosage from 0.5mg to 1mg daily, resulting in a rise in DHT levels from 148 pg/mL to 281 pg/mL, and is considering switching back to finasteride due to continued hair loss. Replies suggest retesting and emphasize the importance of bloodwork before starting treatments.

      community Should I be hopeful? Oral min 5mg dutasteride 1mg

      in Is this regrowth?  22 upvotes 7 months ago
      The conversation discusses hair loss treatments including oral minoxidil 5mg, dutasteride 1mg, and suggestions to use a derma stamp on the scalp. Some users believe these treatments can improve hair condition or at least stabilize loss, while one suggests considering a hair transplant after a year if desired.

      community How to know if shedding is from tren or minoxidil?

      in Minoxidil  5 upvotes 7 months ago
      The user started using trenbolone and minoxidil simultaneously and experienced increased hair shedding, unsure which is causing it. Replies suggest both drugs could cause hair loss, with one advising to stop trenbolone to protect hair and another indicating minoxidil is unlikely the cause due to the timing.

      community 6 months on biotin + minoxidil

      in Progress Pictures  355 upvotes 7 months ago
      A user shared a 6-month progress picture showing improvement in hair loss using biotin and minoxidil. They also mentioned dealing with stress, diet issues, and seborrheic dermatitis.

      community Expectations control for SCUBE3

      in Research/Science  22 upvotes 8 months ago
      SCUBE3, a protein linked to hair growth in moles, was discovered over 25 years ago and is being developed by Amplifica for potential hair loss treatment. Concerns exist about SCUBE3's association with cancer, as it is a protein that promotes cell growth, which could potentially trigger cancer development if used for hair growth therapy.

      community Anything stronger than DUT out there?

      in Finasteride/Dutasteride  14 upvotes 8 months ago
      The conversation discusses seeking a stronger treatment than Dutasteride (DUT) for hair loss. Suggestions include combining DUT with RU58841, increasing DUT dosage, and using transgender hormone replacement therapy or testosterone blockers, though some options may have feminizing side effects.

      community Creatine's effect on Hair Loss and DHT

      in Research/Science  103 upvotes 8 months ago
      A 21-year-old male managed to control his hair loss using Nizoral, RU58841, and finasteride, but experienced increased scalp itchiness after starting creatine, which subsided upon stopping creatine. Users shared mixed experiences on whether creatine affects hair loss, with some reporting negative effects and others seeing no change or defending its benefits.

      community Testosterone in Reference Range Doesn't Cause Hair Loss

      in Research/Science  51 upvotes 9 months ago
      Testosterone within the normal range does not significantly contribute to male pattern baldness (MPB); DHT is the main factor that can be controlled. Genetics play a crucial role in hair loss, and treatments like finasteride and dutasteride, which block DHT, can help despite potentially raising testosterone levels.

      community Can RU58841 stop hairloss for a long time?

      in Research/Science  11 upvotes 11 months ago
      A user is considering using RU58841 to treat hair loss and asks if it can be effective for 4-5 years. Some suggest starting with a lower concentration and debate the safety of RU58841 compared to approved drugs like finasteride.

      community Rosemary oil's potency as a dht blocker

      in Research/Science  65 upvotes 11 months ago
      Rosemary extract showed high inhibitory activity against DHT, similar to finasteride and dutasteride, but the conversation includes skepticism about its effectiveness in humans since the study was done on mice and rosemary oil is often considered ineffective based on personal experiences. Some suggest trying rosemary oil alongside other treatments, while others emphasize the difference between the extract used in the study and the oil.

      community 35 MtF | 16 Months | Minoxidil + Dutasteride + Microneedling + Exosomes. Note that since I'm early in my transition (and I was coming from a bald state), I still have short hair. Very few MtF progress pictures here, I figure this might help some of you.

      in Transgender  130 upvotes 11 months ago
      A 35-year-old transitioning female (MtF) shared her hair regrowth journey using Minoxidil, Dutasteride, Microneedling, and Exosomes, starting from a bald state. Commenters discussed the impressive results, skin care routine, and the effects of estrogen on hair and skin.

      community Anyone else crying themselves to sleep because of the pyrilutamide fail?

      in Technology  43 upvotes 11 months ago
      The conversation is about disappointment with pyrilutamide's performance as a hair loss treatment, with some users expressing interest in other treatments like Verteporfin, GT20029, and RU58841, while others suggest sticking with established treatments like finasteride or dutasteride.