The conversation is about using valproic acid, an anti-seizure medication, as a topical treatment to promote hair growth. The original poster is seeking personal experiences from those who have tried this method.
A 43-year-old man started treatment for hair loss with finasteride, minoxidil, Qilib rebalance, and Trigain Caffeine shampoo, and is taking vitamin D supplements. He hopes to share positive results after a few months.
User is using topical Minoxidil (100 mg/day) and Finasteride (1 mg/day) but experiencing hair growth everywhere except the top of the scalp. They seek advice on improving scalp hair regrowth.
Topical finasteride is almost as effective as oral finasteride with fewer side effects. Users are considering between oral and topical finasteride for hair loss treatment.
The user has been using liposomal topical finasteride since late 2022, progressively increasing the dose, but DHT serum levels remain largely unchanged. Despite using finasteride, minoxidil, microneedling, and ketoconazole, hair condition has neither improved nor worsened.
The conversation is about the potential cost of GT20029 if FDA approved, with estimates around $150/month. Comparisons are made between GT20029, finasteride, and their mechanisms and side effects.
The conversation discusses the delay in the release of GT20029 for hair loss treatment and skepticism about its effectiveness. Participants mention other treatments like verteporfin and advancements in transplant procedures as more realistic options.
A user shared their positive experience with hair regrowth after 3 months using finasteride, minoxidil, and vitamins such as biotin, B5, B6, and C. They took 1.1 mg of oral finasteride, experienced a shedding period initially, and emphasized the importance of consistency.
Keratin microspheres may offer additional mechanisms to combat hair loss compared to minoxidil. The process to create these microspheres is relatively simple and can be done at home with basic equipment.
The conversation is about someone who has tried various dosages of finasteride for hair loss without success and is considering switching to dutasteride, which reduces more DHT. They are asking if others have had issues with finasteride but found dutasteride to be more effective without problems.
The conversation is about whether it's safe to use minoxidil with a mix of stemoxydine, RU58841, alfatradiol, and tretinoin at the same time for hair loss treatment. Concerns were raised about the absorption and effectiveness when these treatments are applied together.
The conversation discusses hair loss treatments, specifically the progress made with Pyrilutamide over 15 months. One person suggests using oral Minoxidil or Dutasteride, but another mentions experiencing negative side effects from oral Finasteride.
User has maintained hairline with minoxidil for 8 years but now seeks to add topical finasteride due to increased hair loss. They request advice on making a homemade finasteride solution, including ingredient recommendations and optimal percentages for ethanol and glycerin.
A user is considering using RU58841 to treat hair loss and asks if it can be effective for 4-5 years. Some suggest starting with a lower concentration and debate the safety of RU58841 compared to approved drugs like finasteride.
The user experienced severe side effects with topical finasteride, continued using Minoxidil, and was advised to try topical dutasteride after a test suggested they might not respond to finasteride. They are hesitant to start the new treatment due to past side effects.
An 18-year-old male used anti-androgens and oral Minoxidil for 10 months to treat hair loss. He initially used 1mg Finasteride and 5% topical Minoxidil for 5 months, then switched to Dutasteride for 4.5 months and inconsistently used 5mg oral Minoxidil for 2 months due to availability issues.
The conversation discusses whether drinking green tea affects hair loss, with one user concerned it might increase DHT levels. The user is already using finasteride and wants to ensure green tea doesn't hinder progress.
The post is a 1-year update on hair loss progress using topical minoxidil and finasteride treatments. The user has seen good progress, especially in transitioning from a Norwood 3 to a Norwood 2 hair loss pattern.
The conversation is about when GT20029, a hair loss treatment, might be available on the grey market, with users discussing the challenges of compounding it and speculating it might be available after phase 2 results, similar to pyri. Specific treatments mentioned are pyri, RU58841, and GT20029.
The conclusion of this conversation is that the user "DuckSeasonCamelSeasn" found that consuming grapefruit juice prior to taking finasteride or dutasteride helped them become a responder to the medications and regain hair growth. However, there are warnings about potential risks and interactions with other medications, so caution should be exercised.
He Shou Wu (Fo Ti) extract was found to prolong the hair growth phase, inhibit 5-alpha-reductase (like finasteride), reduce androgen receptors, and increase growth factors, potentially outperforming minoxidil in recovering hair follicle size after DHT exposure. Two compounds, emodin and TSG, are identified as responsible for these effects and warrant further investigation.
The conversation discusses adding melatonin powder to a topical finasteride solution for hair loss, with one reply suggesting that melatonin may promote faster hair growth but advising against mixing it directly into the solution due to potential instability.
KX-826/pyrilutamide is undergoing an additional one-year safety and efficacy trial in China after a six-month study. Some participants speculate on the reasons for the extended trial and discuss the potential of other treatments.
The user is using finasteride and minoxidil for hair loss but is looking for new treatments. Pyrilutamide and GT20029 are potential future treatments, with Pyrilutamide expected next year and GT20029 possibly by 2027.
User has been on finasteride and switched to Dutasteride 6 months ago, using minoxidil, tretinoin, microneedling, and RU-58841, but still experiencing hair loss. Advice given includes waiting 6-18 months for Dutasteride results and checking if it's definitely MPB.
The conversation discusses a claim that avoiding coffee can lead to significant hair regrowth in individuals with androgenetic alopecia. Participants are skeptical, with some sharing personal anecdotes that contradict the claim, and others discussing the potential role of caffeine in hair loss and the effectiveness of other treatments like finasteride and minoxidil.
Hair growth can be induced without stopping DHT, as seen with Minoxidil. HMI115 may work by promoting follicle growth, not targeting the root cause of hair loss (DHT).