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      community Pyrilutamide phase III clinical trial results released

      in Research/Science  31 upvotes 11 months ago
      Pyrilutamide did not show effectiveness in regrowing hair compared to a placebo, but it may still help maintain existing hair by preventing DHT from causing follicle miniaturization. Some users believe it could be beneficial when used with other treatments like minoxidil, finasteride, and dutasteride.

      community PYRILUTAMIDE PHASE 3 RESULTS : No statistical significance

      in Research/Science  123 upvotes 11 months ago
      The phase 3 trial results for Pyrilutamide showed no significant difference from the control treatment in increasing hair count, leading to the company halting its development. Users discussed their disappointment and skepticism about hair loss treatments, with some mentioning other treatments like Minoxidil, Finasteride, and RU58841.

      community Kintor Phase 2 Results released KX-826 (pyrilutamide)

      in Research/Science  446 upvotes 2 years ago
      Kintor Pharmaceutical's Phase 2 results with the drug Pyrilutamide, a potential alternative to 5-ARI drugs like Finasteride and Dutasteride but without the side effects. It could be used in combination with other topical treatments such as Minoxidil. The safety of the drug has been demonstrated in 6 months of use, however there are still questions about long term efficacy and systemic absorption.

      community 3 years of finasteride and minoxidil

      in Progress Pictures  1252 upvotes 1 year ago
      This conversation is about a user who used finasteride and minoxidil over the course of three years to treat their hair loss, and they achieved great results. They experienced severe shedding when first beginning treatment but eventually saw very noticeable results after one year.

      community Shedding again after 6 months of great results.

      in Minoxidil  15 upvotes 2 months ago
      A user experienced shedding after 7 months on Fin/Min spray despite good results and no change in treatment. Other users noted similar experiences and mentioned that shedding periods can be normal.

      community Getting hit hard by the shed….

      in Progress Pictures  85 upvotes 4 months ago
      A user is experiencing significant hair shedding after starting a treatment regimen of 1mg oral finasteride, 3mg oral minoxidil, 2.5mg biotin, and vitamins. Despite the shedding, they remain optimistic and plan to continue the treatment for a year before making any conclusions.

      community Pyrilutamide update: three months

      in Update  30 upvotes 1 year ago
      A user's 3-month experience with pyrilutamide to reduce hair shedding, and how it may not be strong enough to stop the thinning of their hairline. Other users mentioned the effectiveness of minoxidil and finasteride for treating hair loss.

      community 6.5 Month Progression 33/Female

      in Female  41 upvotes 1 year ago
      Maintaining scalp hair and minimizing shedding, treatments used such as Procapil, supplements, topical caffeine, topical estrogen, and scalp massage; suggestions for anagen extenders or pharmaceuticals to help with a short anagen phase.

      community 4 month topical fin and min progress

      in Progress Pictures  40 upvotes 4 months ago
      The user has been using topical minoxidil 6% and finasteride 0.05% once daily, along with microneedling, vitamins, and nizoral shampoo. They recently increased the topical treatments to twice daily for faster results, experiencing only initial shedding.

      community Surprisingly thorough study on He-Shou-Wu/Fo Ti

      in Research/Science  14 upvotes 1 year ago
      He Shou Wu (Fo Ti) extract was found to prolong the hair growth phase, inhibit 5-alpha-reductase (like finasteride), reduce androgen receptors, and increase growth factors, potentially outperforming minoxidil in recovering hair follicle size after DHT exposure. Two compounds, emodin and TSG, are identified as responsible for these effects and warrant further investigation.

      community 4 Month Update on Pyrilutamide

      in Update  11 upvotes 1 year ago
      Hair loss treatment with Pyrilutamide, Minoxidil, and Finasteride showed improvement after 4 months. Shedding reduced, hair feels stronger and healthier, with no side effects.

      community Update: 7 Months on min, fin and microneedling.

      in Progress Pictures  24 upvotes 7 months ago
      The user has been using a combination of Minoxidil, finasteride, microneedling, Nizoral shampoo, biotin, and multivitamins for 7 months to treat hair loss. They experienced shedding between months 5-6 but have noticed hair regrowth, especially around the crown area, and less shedding recently.

      community (M24) ~5 years progress on Fin & Min. AMA

      in Progress Pictures  1697 upvotes 1 year ago
      The user "LandB4TimeIn3D" shared their hair loss progress using finasteride (Fin) and minoxidil (Min). They experienced shedding for the first few years but saw significant regrowth after about 2-3 years. They also mentioned using topical liquid minoxidil twice a day.

      community I'm tired, boss. I fought. Now I seem to be losing.

      in Update  23 upvotes 1 year ago
      The user is struggling with hair loss despite using finasteride, minoxidil, and ketoconazole, and addressing vitamin D and ferritin deficiencies. They experienced a temporary improvement but are now shedding hair again and feeling stressed.

      community Does anyone have any experience with Stemoxydine?

      in Product  11 upvotes 2 years ago
      Using Stemoxydine, a hair growth promoter, in conjunction with Fin and Minoxidil to help counter shedding induced by the latter two treatments. Another user also shared their experience of using Stemoxydine for three months along with dermastamp.

      community Pryri journey update 2 weeks so far.

      in Treatment  15 upvotes 2 years ago
      A 2-week journey with Pyri, which is producing positive effects on hair texture and reduced shedding; Minoxidil and derma needling are being used as treatments.

      community Progress Pics 2 years fin 1mg, 1 year min

      in Progress Pictures  277 upvotes 4 months ago
      A user shared their hair loss progress after 2 years of finasteride and 1 year of minoxidil, along with occasional microneedling and regular exercise. They experienced initial shedding but saw significant improvement after 4 months.

      community Stop expecting results in 2 months!

      in Treatment  125 upvotes 6 months ago
      People discussing hair loss treatments emphasize the need for patience, as results from using finasteride and minoxidil can take 8-12 months or longer. Some users report early signs of improvement, while others experience continued shedding or slower progress.

      community Pyrilutamide 5 months results (before, after pics)

      in Progress Pictures  196 upvotes 1 year ago
      Tae147 has shared results of using pyrilutamide, a 5% concentration topical solution applied twice daily, in combination with minoxidil, to reduce scalp itchiness and hair shedding. Other users have shared their experiences with the treatment, as well as questions about its availability on the market.

      community Is this good improvement? 3-4 months in

      in Is this regrowth?  470 upvotes 1 week ago
      The user experienced increased hair density and thickness after 3-4 months using finasteride, minoxidil, dermastamping, ketoconazole, and biotin. They apply minoxidil right after dermastamping without any side effects or shedding.