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      community Melatonin emerging as new treatment for androgenic alopecia?

      in Update  36 upvotes 3 weeks ago
      Melatonin is being considered as a potential treatment for androgenic alopecia, with some users discussing its effects and combining it with other treatments like minoxidil and finasteride. Concerns about melatonin's impact on hormones and side effects from other treatments like ketoconazole were also discussed.

      community 37/m, 9 months progress, topical 5%min and 6%Fin

      in Progress Pictures  175 upvotes 3 weeks ago
      A 37-year-old man experienced significant hair regrowth over nine months using a topical solution of 5% Minoxidil and 0.3% Finasteride. He reported no side effects and noted the treatment's effectiveness despite initial dosage confusion.

      community GT20029 & KX826 Major Updates from Kintor.

      in Research/Science  101 upvotes 1 month ago
      KX826 shows promise as a hair loss treatment with a 10% increase in hair count, but concerns about Kintor's marketing practices and the systemic effects of treatments like GT20029 and RU58841 remain. Users express skepticism and hope, with some preferring traditional treatments like finasteride and minoxidil.

      community Estradiol mesotherapy / idea feedback

      in Female  6 upvotes 1 month ago
      The conversation discusses using estradiol mesotherapy to replicate hormone replacement therapy results while minimizing systemic exposure. It also covers the use of Spironolactone cream, which reportedly has no systemic side effects, and the potential risks of using bicalutamide and Spironolactone in men.

      community I just made 60x of 5mg minoxidil sugar cubes

      in Minoxidil  1327 upvotes 1 month ago
      A user created oral minoxidil sugar cubes due to lack of prescription access, leading to a humorous discussion about unconventional and potentially unsafe methods of using minoxidil. The conversation highlights the lengths people go to for hair growth.

      community December 2023 -> November 2024

      in Progress Pictures  581 upvotes 1 month ago
      The user experienced positive results in hair regrowth using 0.5mg dutasteride daily and 5% topical minoxidil, with no negative side effects except reduced chest/beard hair density. They plan to continue this routine for two years before possibly reducing the dutasteride dose.
      Can I Start Hair Regrowth Treatments at 30? Looking for Recommendations!

      community Can I Start Hair Regrowth Treatments at 30? Looking for Recommendations!

      in General  119 upvotes 1 month ago
      A 30-year-old is considering starting hair regrowth treatments and is seeking advice on medications like minoxidil and finasteride, as well as other therapies. Users suggest starting with the "big 4" treatments and share that many have seen success even when starting later in life.
      Guys I need advice more hairs in the drain

      community Guys I need advice more hairs in the drain

      in Journals / Progress Pictures  217 upvotes 1 month ago
      The user is experiencing significant hair shedding after starting dutasteride, which is considered a normal part of the treatment process. Despite the shedding, the user notes some improvement in hairline appearance and is seeking advice and reassurance.

      community Bile Acid-Mediated DHT Dysregulation Hypothesis

      in Research/Science  13 upvotes 2 months ago
      Elevated bile acids can inhibit the enzyme AKR1C2, leading to increased DHT levels, which may accelerate hair loss in those predisposed to androgenetic alopecia. Treatments mentioned include topical minoxidil and finasteride.

      community 10month fin/min - micro-needling and rosemary biotin & more

      in Minoxidil  635 upvotes 2 months ago
      The conversation discusses a hair loss treatment routine involving daily minoxidil, finasteride, micro-needling, rosemary oil, and biotin supplements. The user shares personal experiences, noting no side effects from finasteride and emphasizing the importance of a healthy lifestyle in preventing hair loss.

      community 1 year results finasteride and minoxidil once daily nothing else

      in Update  850 upvotes 2 months ago
      The user experienced significant hair regrowth after one year of using finasteride, minoxidil, and Nizoral shampoo, with no side effects reported. They noted improved social interactions and emphasized the importance of consistency in treatment.

      community Dutasteride High Libido. How come we don't talk about this?

      in Finasteride/Dutasteride  208 upvotes 2 months ago
      Dutasteride and finasteride can affect libido differently, with some experiencing increased libido and others decreased libido or erectile dysfunction. Dutasteride may increase testosterone levels but can also cause side effects like liver enzyme changes, while topical finasteride may have fewer sexual side effects.

      community Pyrilutamide ,the molecule’s true nature

      in Research  302 upvotes 4 months ago
      Pyrilutamide is a selective AR antagonist with a high binding affinity, making it effective in competing with DHT for androgen receptors. The 1% concentration is more effective than the 0.5%, but the latter may suffice for mild hair loss; the drug is considered a good option for those avoiding 5AR blockers due to side effects.

      community High Nicotine use and Hair Loss

      in Chat  84 upvotes 4 months ago
      Heavy nicotine use can lead to hair thinning and loss, but quitting can reverse these effects. The user noticed significant hair regrowth after quitting vaping.
      Topical Dutasteride - Non-Hormonal, Side Effect Free 5ARI?

      community Topical Dutasteride - Non-Hormonal, Side Effect Free 5ARI?

      in Treatments  451 upvotes 4 months ago
      Topical dutasteride is suggested as a low side-effect treatment for hair loss, with a proposed dose of 0.025% 1ml/day. It is considered better than finasteride due to its even inhibition of DHT isoforms and lower systemic absorption.

      community Topical Dutasteride 0.025% 2ml once a week

      in Treatment  9 upvotes 5 months ago
      A user discusses using topical dutasteride 0.025% once a week for hair maintenance, alongside fortified minoxidil, RU58841, and Reviv Hair Serum. They seek feedback on the effectiveness of this regimen.

      community Stem Cells May Get Rid Of Balding FOREVER!

      in Technology  7 upvotes 5 months ago
      Stem cell therapy shows promise in treating hair loss by mimicking DHT-resistant cells from the back of the head. Traditional treatments like finasteride are also discussed, but stem cells could potentially offer a more permanent solution.

      community Topical fin and min and swallowing semen

      in Finasteride/Dutasteride  118 upvotes 6 months ago
      A user asked if it's safe to swallow semen from a partner using topical finasteride and minoxidil. Responses varied, but most suggested it's likely safe, with minimal risk from small amounts of finasteride in semen.

      community M20 1.5 months vs 8 months fin + min

      in Is this regrowth?  6 upvotes 7 months ago
      A 20-year-old male has been using 1mg finasteride and 5% minoxidil daily for 1.5 to 8 months and is unsure about regrowth. Suggestions include continuing the treatment, trying microneedling, or considering oral minoxidil.

      community Androgenic alopecia exclusively on the vertex of the scalp

      in Chat  6 upvotes 7 months ago
      A user experienced androgenic alopecia starting at the vertex without frontal hairline recession and is seeking information on this pattern. Another user noted that vertex or diffuse hair loss is common among men.