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      community Bile Acid-Mediated DHT Dysregulation Hypothesis

      in Research/Science  13 upvotes 1 month ago
      Elevated bile acids can inhibit the enzyme AKR1C2, leading to increased DHT levels, which may accelerate hair loss in those predisposed to androgenetic alopecia. Treatments mentioned include topical minoxidil and finasteride.

      community 10month fin/min - micro-needling and rosemary biotin & more

      in Minoxidil  635 upvotes 1 month ago
      The conversation discusses a hair loss treatment routine involving daily minoxidil, finasteride, micro-needling, rosemary oil, and biotin supplements. The user shares personal experiences, noting no side effects from finasteride and emphasizing the importance of a healthy lifestyle in preventing hair loss.

      community 1 year results finasteride and minoxidil once daily nothing else

      in Update  847 upvotes 1 month ago
      The user experienced significant hair regrowth after one year of using finasteride, minoxidil, and Nizoral shampoo, with no side effects reported. They noted improved social interactions and emphasized the importance of consistency in treatment.

      community How to Keep Your Hair on Steroids

      in Treatment  17 upvotes 3 months ago
      To minimize hair loss while using steroids, use finasteride or dutasteride and apply topical anti-androgens like RU58841. Avoid high doses of hair-toxic steroids; prefer testosterone, nandrolone, and boldenone.

      community Pyrilutamide ,the molecule’s true nature

      in Research  302 upvotes 4 months ago
      Pyrilutamide is a selective AR antagonist with a high binding affinity, making it effective in competing with DHT for androgen receptors. The 1% concentration is more effective than the 0.5%, but the latter may suffice for mild hair loss; the drug is considered a good option for those avoiding 5AR blockers due to side effects.

      community Stem Cells May Get Rid Of Balding FOREVER!

      in Technology  7 upvotes 5 months ago
      Stem cell therapy shows promise in treating hair loss by mimicking DHT-resistant cells from the back of the head. Traditional treatments like finasteride are also discussed, but stem cells could potentially offer a more permanent solution.

      community M20 1.5 months vs 8 months fin + min

      in Is this regrowth?  6 upvotes 7 months ago
      A 20-year-old male has been using 1mg finasteride and 5% minoxidil daily for 1.5 to 8 months and is unsure about regrowth. Suggestions include continuing the treatment, trying microneedling, or considering oral minoxidil.

      community Androgenic alopecia exclusively on the vertex of the scalp

      in Chat  6 upvotes 7 months ago
      A user experienced androgenic alopecia starting at the vertex without frontal hairline recession and is seeking information on this pattern. Another user noted that vertex or diffuse hair loss is common among men.

      community Massive hair gains! Hope! May this post be a light to you in dark phases when all other lights go out

      in Progress Pictures  193 upvotes 7 months ago
      A 27-year-old man saw significant hair regrowth after starting a regimen in January that included topical minoxidil with finasteride, vitamins D and B12, fish oil, zinc with magnesium, quitting smoking, and intermittent fasting. People commented on the effectiveness of minoxidil in Southern populations and asked about the details and timeline of his treatment.

      community One year later, fin won't work for everyone

      in Progress Pictures  77 upvotes 7 months ago
      The conversation is about a user's experience with finasteride not improving their hair loss and considering dutasteride as a last resort. Some users believe the user's hair appears stabilized, while others suggest surgery or patience, and one mentions heart issues as a reason for not using minoxidil.

      community Anyone else got a folder on their phone full of scalp shots 😂

      in Satire  633 upvotes 8 months ago
      People are sharing their experiences of keeping a hidden folder on their phones with photos documenting their hair loss. Some users discuss the emotional impact, while one mentions using dutasteride and oral minoxidil without noticeable change.

      community How does finasteride leave your body?

      in Chat  13 upvotes 8 months ago
      Finasteride is metabolized in the liver and excreted through urine and feces. Users humorously discuss its excretion, with one joking about it being expelled through ejaculation.

      community Late responders on finasteride alone

      in Treatment  16 upvotes 9 months ago
      The conversation is about someone who has not seen hair regrowth after 6 months on finasteride alone, asking if others have experienced delayed results. Some responses indicate that results can sometimes be seen after 12 months, with full effects up to 24 months.

      community 3 month of profess with fin and minoxidil

      in Progress Pictures  123 upvotes 9 months ago
      The conversation discusses a user's three-month progress using topical finasteride once a day, 6% minoxidil at night, and weekly dermastamping at 1.25mm for hair loss. Commenters note the impressive results and discuss application methods and safety precautions for family members.

      community High DHT with finasteride. Help!

      in Finasteride/Dutasteride  6 upvotes 10 months ago
      Despite using 5% minoxidil, 0.1% finasteride, and other treatments like microneedling, MK-677, and Cialis, hair loss continues with high testosterone and DHT levels. Considering oral dutasteride but concerned about further increasing testosterone levels.

      community Have you tried Biotin supplements for your hair?

      in Product  25 upvotes 1 year ago
      People shared that Biotin supplements did not improve their hair loss and some experienced stronger nails or more pimples. They suggested trying finasteride or minoxidil instead for hair loss treatment.

      community Minoxidil seems to not work anymore this sucks

      in Progress Pictures  32 upvotes 1 year ago
      A user reported that Minoxidil, a hair growth treatment, stopped working for them despite initial success. Other users suggested not taking breaks from the treatment, checking for fake products, trying microneedling, using oral Minoxidil, combining Minoxidil with tretinoin, and using finasteride.

      community What's up with everyone microneedling 1.5 mm per week?

      in Microneedling  52 upvotes 1 year ago
      The conversation is about microneedling for hair loss. The conclusion is that there are differing opinions on the depth and frequency of microneedling, with some studies suggesting positive results with 1.5mm depth once a week, while others prefer lower depths and less frequent sessions.

      community What’s your experience with RU58841?

      in Treatment  21 upvotes 1 year ago
      People shared mixed experiences with RU58841 for hair loss; one person saw no improvement, another had significant gains and uses it with finasteride, while a third had an allergic reaction to the premixed solution. Some mix RU58841 powder into minoxidil themselves.

      community 1 year later, min 2ml daily, fin 1mg to 0.5 daily + microneedling

      in Finasteride/Dutasteride  147 upvotes 1 year ago
      The user, Salt_Ad6339, shares their positive experience with hair regrowth after using minoxidil and finasteride for a year, along with microneedling. However, they also mention experiencing chest/nipple pain and suspect it may be a side effect of finasteride. They decide to stop using it for now and see if minoxidil alone can maintain their hair. Other users in the conversation discuss the potential side effects of finasteride and suggest using an aromatase inhibitor to counteract them.

      community The "DHT" itch myth - it's more complicated

      in Product  7 upvotes 1 year ago
      A user found that scalp itch might be linked to inflammation rather than DHT alone and noticed hair improvement with certain cancer drugs. They also discovered that black seed oil relieved their scalp itch and are experimenting with a mix of essential oils for dry scalp, questioning if oils affect minoxidil absorption.

      community Minoxidil + Gym + Cutting. Is it bad?

      in Minoxidil  38 upvotes 1 year ago
      A user is concerned about weight loss stagnation while using minoxidil and finasteride during a calorie-cutting diet. Responses suggest water retention or a weight loss plateau as possible causes.

      community Sweet Lord my DHT itch is finally gone

      in Chat  49 upvotes 1 year ago
      Hair loss itch stopped by adding RU58841 to treatment. Topical Finasteride and Pyrilutamide also mentioned as potential itch solutions.

      community Never had better results than a few drops of minoxidil under the tongue. I've tried various combinations.

      in Minoxidil  11 upvotes 2 years ago
      The user reports the best results for hairline regrowth using 3 drops of minoxidil under the tongue once daily, after trying various treatments including loniten, topical minoxidil with estrogen, dutasteride, and finasteride. Additional regimen includes occasional tretinoin, collagen peptides, crude oil massages, violet ray device, nizoral, and Listerine for scalp health.

      community A new meta-analysis of 23 studies has confirmed that 5 milligrams a day of oral dutasteride had the highest probability of reducing male hair loss, followed by 5 milligrams a day of oral finasteride, followed by 5 milligrams of oral minoxidil, followed by 1 milligram a day of oral finasteride

      in Research/Science  82 upvotes 2 years ago
      Oral dutasteride (0.5mg) is most effective for male hair loss, followed by oral finasteride (5mg), oral minoxidil (5mg), and oral finasteride (1mg). Different treatments have benefits and side effects, and results don't apply to women's hair loss.