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      community Reaction to High Dose Minoxidil After Year of Use

      in Minoxidil  9 upvotes 5 years ago
      A male with early-stage hair loss experienced severe side effects, including sexual dysfunction from finasteride and increased heart rate and fatigue from high-dose minoxidil, leading to discontinuation of both treatments. He is now relying on DHT-blocking shampoos and awaiting new treatments.

      community KX-826: Long-Term Safety Results are out!

      in Research/Science  158 upvotes 1 month ago
      KX-826 initially improves hair growth but declines after 24 weeks, with mild itching as a side effect. Combining it with minoxidil and finasteride may improve results, but long-term effectiveness is uncertain.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 3 months ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community PSA: Caffeine and Hair Transplants

      in Transplants  29 upvotes 3 months ago
      A user shared their experience with a hair transplant, emphasizing the importance of avoiding caffeine 7 days before the procedure. Ignoring this advice led to reduced effectiveness of the numbing agent, causing significant discomfort during the transplant.

      community 27/M closing in on a year of fin and min, feel like it’s only gotten worse.

      in Chat  62 upvotes 3 months ago
      A user reported no improvement in hair loss after nearly a year of using 1mg oral finasteride, topical minoxidil twice daily, and weekly microneedling. Other users suggested the possibility of DUPA or retrograde alopecia and mentioned that treatments might only slow down hair loss rather than regrow hair.

      community 10.5 months. Oral propecia, topical minoxidil (once daily) derma roller. And for the last two (2) months, I've been doing the bald showers after leg workouts... Biotin and Omega 3 age 35. Loses a lot of hair a day, over 150

      in Progress Pictures  243 upvotes 3 months ago
      A user shared their 10.5-month progress using oral finasteride, topical minoxidil, a derma roller, biotin, and Omega 3, despite losing over 150 hairs daily. They also mentioned starting "bald showers" after leg workouts for the last two months.

      community A hill on which I will die: The DHT itch absolutely exists

      in Research/Science  208 upvotes 6 months ago
      The DHT itch is linked to hair loss and persists despite finasteride use; switching to dutasteride helped alleviate the itch and promoted regrowth. Some users suggest seborrheic dermatitis as a cause and recommend treatments like medicated shampoos, vitamin D, and minoxidil.

      community Minoxidil Finasteride heart problems

      in Update  97 upvotes 6 months ago
      A user experienced heart problems after taking 1mg finasteride and 2.5mg oral minoxidil and is considering quitting minoxidil. Others discussed their experiences with heart issues and minoxidil, with some suggesting topical minoxidil as a safer alternative.

      community Stop expecting results in 2 months!

      in Treatment  125 upvotes 6 months ago
      People discussing hair loss treatments emphasize the need for patience, as results from using finasteride and minoxidil can take 8-12 months or longer. Some users report early signs of improvement, while others experience continued shedding or slower progress.

      community Sunlight: Does it Stimulate Hair Growth or Hair Loss?

      in Research/Science  61 upvotes 7 months ago
      The conversation discusses whether sunlight exposure affects hair growth or loss, with mixed anecdotes and theories but no clear consensus. Some suggest moderate sunlight can benefit hair by providing vitamin D, while others doubt its effectiveness compared to treatments like Minoxidil or finasteride.

      community Breezula will hit the market in 2026, Cosmo Pharmaceuticals statement!

      in Product  52 upvotes 8 months ago
      Breezula, a hair loss treatment, is expected to cost around $100 a month and is anticipated to be released in 2026. The effectiveness of Breezula is debated, with some suggesting it loses effectiveness over time and others arguing it maintains hair compared to baseline.

      community 1.5 months in, looking pretty good

      in Progress Pictures  357 upvotes 8 months ago
      The conversation is about a user's positive experience with hair loss treatment after 1.5 months, using topical finasteride, minoxidil, keto shampoo, and minoxidil shampoo, despite the drying effect of keto shampoo and a change in hair texture due to accutane. Responses include congratulations, personal experiences with hair loss treatments, and a mention of accutane's negative impact on hair.

      community 2 months update, experiencing massive gains

      in Progress Pictures  444 upvotes 10 months ago
      A user reports significant hair regrowth after 2 months using Minoxidil, Finasteride, oiling, derma rolling, and taking multivitamins, omega 3, and vitamin D. Some users discuss the frequency of derma rolling, with varying practices ranging from once every two weeks to four times a week.

      community Can low level of vitamins cause hair loss?

      in Research/Science  21 upvotes 11 months ago
      The conversation is about whether low vitamin levels can cause hair loss. The consensus is that the user's vitamin levels are normal and unlikely to affect hair loss or the effectiveness of finasteride and minoxidil treatments.

      community What’s your nuclear protocol???

      in Chat  19 upvotes 1 year ago
      People discussed their intense hair loss treatments, including the use of dutasteride, RU58841, minoxidil, tretinoin, essential oils, microneedling, and various topical sprays. Some users reported success with these methods in preventing hair loss and stimulating hair growth.

      community Norwood 6 trying the bounce back

      in Progress Pictures  198 upvotes 1 year ago
      A 37-year-old who started losing hair in their early 20s tried minoxidil with little effect, then experienced more loss until 2023. They are now using a treatment including finasteride, minoxidil, biotin, saw palmetto shampoo, and micro needling, and are seeing early positive results.

      community Coffee and androgenetic alopecia

      in Research/Science  13 upvotes 1 year ago
      The conversation discusses a claim that avoiding coffee can lead to significant hair regrowth in individuals with androgenetic alopecia. Participants are skeptical, with some sharing personal anecdotes that contradict the claim, and others discussing the potential role of caffeine in hair loss and the effectiveness of other treatments like finasteride and minoxidil.