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12 companies having drugs or therapies in clinical trials during 2023, with various molecules and phases of trial; the probability that some may fail; and progress being made in the field.

People are discussing how to apply tretinoin to the scalp for hair loss treatment and managing scalp dryness. Specific treatments mentioned include tretinoin, minoxidil (Min), finasteride (Fin), and RU58841 (RU).

Microneedling for hair restoration involves daily use of a 0.3 mm device and weekly use of a 0.5 mm device. Combining microneedling with Minoxidil can enhance hair growth.

A user's experience with an expensive hair loss clinic that failed to produce the desired results, and advice from other users on treatments such as Minoxidil, Finasteride, and RU58841.

Switching from finasteride to dutasteride as a treatment for hair loss, and discussing possible side effects or results of the switch.

A user shared their experience with a 2000 FUE hair transplant at Hasson and Wong, noting significant improvement 7.5 months post-op. They also used finasteride and dutasteride to slow hair loss.

Late 20s woman struggles with worsening hair loss and tried various treatments without success. Now trying spironolactone and ketokonazole shampoo, hoping for improvement.

21-year-old female experiencing hair loss and visible scalp seeks advice on PRP effectiveness. Currently taking spironolactone and krimson for high androgens, unsure if PRP can be done with these medications.

Hair loss treatments include finasteride and spironolactone. Low vitamin D levels may contribute to hair loss, and normalizing levels could potentially help regrowth.

The conversation is about the safety of Breezula compared to RU58841 for hair loss treatment. The user believes Breezula is safer but less effective than RU58841.

The conversation discusses the approval of Kintor Pharmaceutical's AR-PROTAC (GT20029) for clinical trials in China for acne and androgenic alopecia. One user expresses optimism about new treatments being developed and seeks clarification on how the new drug works, specifically if it temporarily degrades the AR protein to reduce DHT sensitivity in hair follicles.

A questionable paper which suggests that 5% topical spironolactone is more effective than 0.1% topical finasteride for treating hair loss. It should be taken with a grain of salt due to the journal it was published in.

The user experienced hair thinning despite using finasteride and switched to a ketoconazole shampoo without sulfates to address scalp itching and dandruff. They hope this will stop further hair thinning.

Finasteride is effective for treating male pattern baldness (MPB) with minimal side effects, and topical finasteride is similarly effective. Dutasteride is also effective but less understood, and Minoxidil is less effective than Finasteride.

A 23-year-old experiencing hair loss tried olive oil, coconut oil, and hair growth shampoos without success. They are seeking advice on whether to start treatments like Minoxidil, finasteride, or RU58841.

A 28-year-old is experiencing worsening hair loss despite using finasteride, minoxidil, microneedling, Nizoral, Selsun Blue, and supplements. Suggestions include trying Dutasteride or considering a hair transplant if no improvement is seen by the two-year mark.

The conversation discusses new hair loss treatments like stem cell therapy, exosome treatments, and DHI, with mentions of GT20029, Amp303, and Plated PRP Serum as promising options. It also notes the use of dutasteride, topical finasteride, and minoxidil, but the focus is on non-hormonal innovations.

The conversation discusses the trustworthiness of Indian medications for hair loss, with some users mentioning they have purchased Minoxidil, finasteride, and RU58841 from India. Concerns include dosage and ingredient variations, but no harmful effects are noted.

A user shared their hair regrowth progress from using Minoxidil 5% and Finasteride 2.5 mg since August 2024, reporting no side effects. They cut 5mg Finasteride pills in half and take them every other day, and recommend consulting a dermatologist for personalized advice.

The user experienced significant hair regrowth after one year on male-to-female hormone replacement therapy (HRT) and nine months using minoxidil and finasteride. They noted a reduction in body hair and attributed much of the hair regrowth to the addition of minoxidil.

Dutasteride at 2.5mg is considered a potential hair loss cure due to its DHT-blocking ability, but there are concerns about side effects and individual responses. Minoxidil, finasteride, and RU58841 are also discussed, with mixed opinions on their effectiveness and safety.

A Dutasteride Simulator predicts serum dutasteride, serum DHT, and scalp DHT levels using models from research papers. It simulates various dosing schedules to determine steady-state effects and visualizes outcomes, including hair growth-related scalp DHT suppression.

A user shared their six-month progress using oral finasteride (1mg) and topical minoxidil (5%) for hair loss, with additional inconsistent microneedling. The combination showed noticeable improvement, and the user microneedles twice a week.

Concerns about hair loss treatments, specifically finasteride and minoxidil, and doubts about a bald dermatologist prescribing them. Users recommend finding a dermatologist who prescribes effective treatments or exploring online options for finasteride.

Minoxidil improved the user's hairline after 6 months, with visible baby hairs and less scalp visibility. The user plans to start finasteride after a year, considering health checks first.

Nutrafol is criticized for misleading advertising, as it doesn't effectively regrow hair. Effective treatments mentioned include minoxidil and finasteride.

People are discussing hair loss treatments, including finasteride, minoxidil, and dutasteride, focusing on maintenance and potential regrowth. Some users joke about unrealistic expectations, while others share experiences and advice on treatment options.

Microneedle pens for hair loss are harder to find on Amazon due to FDA regulations on needle length. Users suggest buying from AliExpress or Temu instead.

A 28-year-old woman with genetic hair loss has tried various treatments, including oral minoxidil, finasteride, dutasteride, vitamins, ketoconazole shampoo, exosome needling, and hair extensions. She plans to pause treatments for pregnancy and is concerned about potential hair loss during that time.

The user experienced significant hair regrowth and darkening after 4.5 months using 1 mg Finasteride and 5% Minoxidil. Despite improvements, they are still considering a hair transplant for a better hairline.