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      community No, Finasteride as a treatment for MPB was not an "accident"

      in Research/Science  105 upvotes 3 years ago
      Finasteride was intentionally developed to treat BPH and later approved for male pattern baldness (MPB) due to its 5AR inhibition effects. The delay in MPB approval was due to concerns about off-label use for female hirsutism and the prioritization of treating a more debilitating condition.

      community SETIPIPRANT PGE2 GROUP BUY AND PIONEERING HAIR GROWTH

       7 upvotes 8 years ago
      The conversation is about a user seeking help with hair regrowth treatments, specifically mentioning Setipiprant, Minoxidil, Finasteride, and RU58841. The user is trying to contact forum members for guidance on making and using these treatments.

      community Female AGA - Low Cortisol/Low DHEA

      in Female  6 upvotes 1 year ago
      Female (37) experiencing hair loss for 5 years, tried max dose of spiro and oral + topical minox without success. Discovered low cortisol and low DHEA levels, seeking functional medicine practitioner for help.

      community Oxytocin, empathy, hair, and cinnamon

      in General  87 upvotes 3 months ago
      Low oxytocin levels in hair are linked to reduced empathy and may affect hair growth. Cinnamic acid can promote hair growth by activating oxytocin receptors.

      community Starting Finasterid with Vitamin defficiancies

      in Treatment  1 upvotes 3 months ago
      The user started finasteride and experienced increased shedding for five months. They are concerned about how low vitamin levels might affect the shedding and effectiveness of finasteride.

      community Low iron and hair loss connection

      in Female  16 upvotes 6 months ago
      A 39-year-old woman noticed hair thinning and found she has an iron deficiency, which may be linked to hair loss. Suggestions included seeing a dermatologist, using spironolactone, and minoxidil.

      community Why does finasteride stop working?

      in Finasteride/Dutasteride  26 upvotes 1 month ago
      Finasteride may seem less effective over time due to increased DHT sensitivity or aging, but it still suppresses DHT. Switching to dutasteride offers stronger DHT suppression but may increase estrogen levels.

      community 1ish year on fin and no improvement

      in Is this regrowth?  86 upvotes 1 month ago
      The user has been using finasteride for over a year without improvement and recently started oral minoxidil. Suggestions include trying dutasteride and continuing minoxidil for potential regrowth.

      community Pyrilutamide ,the molecule’s true nature

      in Research  302 upvotes 3 months ago
      Pyrilutamide is a selective AR antagonist with a high binding affinity, making it effective in competing with DHT for androgen receptors. The 1% concentration is more effective than the 0.5%, but the latter may suffice for mild hair loss; the drug is considered a good option for those avoiding 5AR blockers due to side effects.

      community Hormones and hair loss (23F)

       7 upvotes 8 years ago
      The user is experiencing severe hair loss, possibly due to telogen effluvium, after stress, poor nutrition, and hormonal changes. They are using Nizoral and supplements but are considering hormonal treatments like spironolactone despite previous side effects.

      community 3+ months of shedding with no end in sight

      in Finasteride/Dutasteride  9 upvotes 4 months ago
      A user has been on 1mg finasteride daily for 10 months, initially seeing great results, but started shedding heavily again at the 7-month mark. They are considering whether to continue with finasteride or switch to dutasteride.

      community 2 months of topical minoxidil (5%) use and there is a shadow now!

      in Transgender  192 upvotes 1 year ago
      The post discusses the user's experience with topical minoxidil (5%) for hair loss, showing some improvement after 2 months. Suggestions from others include keeping the hair shorter on the sides and back, adding finasteride for better results, and considering a shaved head look, though the latter was debated for its femininity.

      community Trans: Do I need to use Finnasteride?

      in Transgender 1 year ago
      A transgender individual is starting spironolactone and estradiol for hormone replacement therapy (HRT) and is considering adding finasteride to help with hair loss. They are also planning to use minoxidil and microneedle, but are unsure if they need to use another anti-androgen or more aggressive treatments. A respondent advises against using pyri and suggests waiting to see if the HRT alone is sufficient before becoming dependent on minoxidil.

      community Estrogen lowering supplements while on Finasteride?

      in Treatment  7 upvotes 2 years ago
      The conversation discusses using aromatase inhibiting supplements like DIM and Grape Seed extract while on finasteride for hair loss treatment. Users share their experiences and opinions on combining these supplements with finasteride.

      community Another clueless guy fearmongering and spreading misinformation

      in Chat  251 upvotes 9 months ago
      The conversation discusses hair loss treatments, with some users advocating for finasteride and minoxidil, while others express concerns about potential side effects of finasteride. A social media influencer is criticized for promoting scalp massages and minoxidil over finasteride, which some believe is misinformation.