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      community Why isnt topical fin talked about more?

      in Chat  43 upvotes 1 week ago
      Topical finasteride is less popular due to inconvenience, cost, and availability, while oral finasteride is favored for ease and safety. Some users experience side effects with topical use, but find it effective with minoxidil, though opinions on its efficacy vary.

      community Why Diffuse Thinning is Worse Than a Receding Hairline

      in Research/Science  149 upvotes 3 weeks ago
      Diffuse thinning is worse than a receding hairline as it affects the entire scalp, complicating styling and hair transplants. Treatments like finasteride, minoxidil, dutasteride, and RU58841 are mentioned, with some users noting improved hair density.

      community 24M still losing on Dut and Oral Min

      in Update  26 upvotes 1 month ago
      A 24-year-old male is losing hair despite using dutasteride and oral minoxidil, with no regrowth from April to October 2024. He is considering increasing his dosage and looking for cheaper prescriptions, while others recommend consulting a trichologist or trying different treatments.

      community KX-826: Long-Term Safety Results are out!

      in Research/Science  158 upvotes 1 month ago
      KX-826 initially improves hair growth but declines after 24 weeks, with mild itching as a side effect. Combining it with minoxidil and finasteride may improve results, but long-term effectiveness is uncertain.

      community Dutasteride High Libido. How come we don't talk about this?

      in Finasteride/Dutasteride  208 upvotes 1 month ago
      Dutasteride and finasteride can affect libido differently, with some experiencing increased libido and others decreased libido or erectile dysfunction. Dutasteride may increase testosterone levels but can also cause side effects like liver enzyme changes, while topical finasteride may have fewer sexual side effects.

      community Hair follicle cloning is already possible

      in Chat  38 upvotes 1 month ago
      Hair follicle cloning is claimed to be possible but not widely available due to potential safety issues, such as cancer risks. Current treatments like finasteride and dutasteride are not effective for everyone, and there is frustration over limited access to these medications.

      community Are they going to Ban Finasteride in the EU ?

      in Finasteride/Dutasteride  68 upvotes 1 month ago
      There is concern about a potential ban on finasteride in the EU, but many believe it is unlikely unless serious side effects are found. Users rely on finasteride for hair loss and other health benefits, and a petition has been created to oppose any restrictions.

      community People who tolerate dut better than fin?

      in Finasteride/Dutasteride  32 upvotes 1 month ago
      Dutasteride may have fewer side effects than finasteride, with some users experiencing better hair maintenance. Experiences vary, with some preferring dutasteride for fewer side effects, while others see no significant hair improvement.

      community Fin year 1 vs year 4. Am I losing ground?

      in Progress Pictures  28 upvotes 1 month ago
      The conversation is about hair loss treatments, focusing on finasteride and considering a switch to dutasteride due to hairline recession. Users suggest trying minoxidil or dermarolling before switching, while others recommend dutasteride for more aggressive hair loss.

      community Low dose oral minoxidil, any success stories?

      in Minoxidil  13 upvotes 2 months ago
      Low-dose oral minoxidil shows mixed results, with some users experiencing hair regrowth and others seeing no significant change. Finasteride is also commonly used, often in combination with minoxidil, and is generally considered effective with a low rate of side effects.

      community ~2.5 months min, is this good progress?

      in Is this regrowth?  415 upvotes 2 months ago
      The user reported significant hair regrowth after 2.5 months using 5% minoxidil, later switching to 10% minoxidil, finasteride, and oral minoxidil. The combination of topical and oral treatments showed impressive progress with minimal side effects.

      community DHT is about to get smashed ….

      in Update  804 upvotes 2 months ago
      The conversation discusses hair loss treatments like topical finasteride with minoxidil, oral dutasteride, and essential oils. Oral treatments like dutasteride and finasteride are seen as more effective, though some prefer topicals to avoid side effects.

      community FINASTRIDE and switch to DUTASTRIDE, my experience

      in Progress Pictures  134 upvotes 2 months ago
      The user shared their experience with Finasteride and Dutasteride for hair loss. They initially had success with Finasteride but switched to Dutasteride after experiencing shedding, which continued, and are now considering a hair transplant.

      community How does hair loss and recovery work?

      in Chat  12 upvotes 2 months ago
      Hair loss varies due to genetic sensitivity to DHT and other factors. Treatments discussed include finasteride, minoxidil, RU58841, and microneedling.

      community 25M - 4 month progress on min + fin

      in Progress Pictures  258 upvotes 2 months ago
      A 25-year-old shared his 4-month progress using oral minoxidil, oral finasteride, a 1mm dermastamp, Nizoral, and upgraded shampoo and conditioner. He feels he sees some regrowth, though some commenters attribute the change to a different hairstyle.

      community Just find a cure already, I am totally done

      in Chat  161 upvotes 2 months ago
      The conversation is about hair loss treatments, with users recommending finasteride and minoxidil as effective solutions. Some users report side effects, but overall, the consensus is to use these treatments rather than waiting for a cure.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 3 months ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.