A woman with androgenic alopecia has been using birth control, spironolactone, finasteride, and oral minoxidil for hair loss. She sought to change her medications to dutasteride and bicalutamide, but her new dermatologist refused to prescribe them for off-label use.
Finasteride is favored for hair loss due to FDA approval, accessibility, and manageable side effects. Dutasteride, though more effective in reducing DHT, is used off-label and may have more side effects.
The conversation discusses whether finasteride would still be necessary if Verteporfin becomes a successful hair loss treatment. It also explores the sensitivity of transplanted hair to DHT and the potential for off-label use of Verteporfin post hair transplant.
The conversation lists medications, oils, and herbs for hair loss, including FDA-approved treatments like Finasteride and Minoxidil, off-label options like Dutasteride and Clascoterone, and others like RU58841. It also mentions Rosemary oil, Saw palmetto, and Fo-Ti root as non-medical treatments.
Verteporfin and FAK inhibitors being looked at as potential treatments for hair regeneration, with updates on the unofficial off-label human trial being discussed.
Finasteride was intentionally developed to treat BPH and later approved for male pattern baldness (MPB) due to its 5AR inhibition effects. The delay in MPB approval was due to concerns about off-label use for female hirsutism and the prioritization of treating a more debilitating condition.
A user ordered Alpha Plus from Anagenica, expecting it to contain specific percentages of Fin, Estradiol, Minoxidil, and CB0301. However, the received product's label showed different percentages, including a surprising 25% CB, leading the user to question its safety and accuracy.
The conversation is about the comparison between finasteride and dutasteride for hair loss treatment. The conclusion is that there is more fear around finasteride due to its higher prevalence and being the first line of defense, while dutasteride is less commonly prescribed and used by those who have already tried finasteride without side effects.
The conversation is about someone being prescribed Dutasteride for hair loss. Specific treatments mentioned include Minoxidil, Finasteride, and RU58841.
A user is considering switching from finasteride to dutasteride for hair loss at age 21, worried about potential side effects on bone and brain development. Another user shared their positive experience with dutasteride, noting minimal body hair and no side effects.
User asks for advice on using hair thickening products and their order of application. Experienced styler suggests using thickening tonic with a blow dryer, followed by styling powder and clay, then hair fibers, and finishing with hairspray.
Dutasteride can be prescribed in the U.S. through online services like Dr. B, HiDrB.com, and PushHealth, or by finding a willing dermatologist or PCP. Many users report success with these methods, often at low costs with insurance.
The user is seeking advice on treating male pattern baldness (MPB) while dealing with seborrheic dermatitis, specifically asking about the use of finasteride (Fin) and minoxidil (Min). They are concerned about side effects and are looking for recommendations to improve overall hair thickness, especially on the crown.
Finasteride worked better for frontal scalp hair loss, while dutasteride helped the crown and mid-scalp but worsened the frontal area. The user shared personal experiences and invited open dialogue.
Switching from finasteride 1mg daily to dutasteride 0.5mg daily may offer better hair regrowth. However, if finasteride is effective, fully switching to dutasteride is not advised; instead, adding dutasteride once a week could be beneficial.
A user considering switching from finasteride to dutasteride for hair loss is seeking advice on how to get a prescription, with suggestions to ask their primary care physician or consult a dermatologist, and mentions of telehealth options for obtaining the prescription.
The conversation is about evaluating the effectiveness and affordability of XHC Ginger Shampoo for hair loss. The user lists the ingredients and expresses that it looks promising and inexpensive.
Minoxidil can be applied to the entire scalp, including the hairline, despite labels suggesting otherwise due to lack of specific testing. For best results in treating hair loss, combining minoxidil with finasteride is recommended, as finasteride addresses the underlying cause of male pattern baldness.
The conversation discusses using topical finasteride (0.25% gel) and minoxidil (5% foam) for hair loss, with users sharing experiences about application methods, microneedling, and results. Some users have switched to oral finasteride for convenience and cost-effectiveness, while others discuss the greasy nature of the topical solution.
The conversation discusses using 2.5mg minoxidil and 1mg finasteride capsules daily for hair loss, with the addition of Nizoral shampoo for dandruff. It suggests switching to Selsun Blue if Nizoral worsens the condition.
The user has been using finasteride and topical minoxidil for hair loss but hasn't seen significant regrowth. They are considering adding topical dutasteride and are exploring options like Happy Head for this treatment.
Dutasteride is less commonly prescribed for hair loss because it is not FDA-approved for this purpose, unlike finasteride, which is more accessible and preferred due to fewer side effects. Dutasteride may be more effective in reducing DHT but has a longer half-life and potentially more significant side effects.
Effective treatments for male pattern baldness include finasteride, dutasteride, and oral minoxidil. Non-effective approaches include oils, shampoos, serums, laser therapies, massages, vitamins, and microneedling.
OP used minoxidil for 15 months and pyrilutamide for 46 days, achieving desired results without side effects. Users discussed alternatives like dutasteride and finasteride, with concerns about side effects like erectile dysfunction.
A person mistakenly drank an entire bottle of topical minoxidil, leading to ICU admission with shock and heart failure. The incident highlights the dangers of ingesting topical treatments and the importance of proper usage and dosage.
User is on vacation in Greece and wants to buy tretinoin or isotretinoin to improve Minoxidil absorption. They are considering isotretinoin since it is available over-the-counter in Greece but requires a prescription back home.
FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.
The user experiences increased dandruff from daily use of minoxidil and finasteride, and seeks shampoo recommendations for an oily scalp that can address dandruff and aid hair restoration. They found Anaphase and an Indian herbal shampoo ineffective.