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      community No, Finasteride as a treatment for MPB was not an "accident"

      in Research/Science  105 upvotes 3 years ago
      Finasteride was intentionally developed to treat BPH and later approved for male pattern baldness (MPB) due to its 5AR inhibition effects. The delay in MPB approval was due to concerns about off-label use for female hirsutism and the prioritization of treating a more debilitating condition.

      community Alpha plus from Anagenica - 25%CB???

      in Product  2 upvotes 1 year ago
      A user ordered Alpha Plus from Anagenica, expecting it to contain specific percentages of Fin, Estradiol, Minoxidil, and CB0301. However, the received product's label showed different percentages, including a surprising 25% CB, leading the user to question its safety and accuracy.

      community Why is there more "fear" around on finasteride than around dutasteride

      in Chat  18 upvotes 1 year ago
      The conversation is about the comparison between finasteride and dutasteride for hair loss treatment. The conclusion is that there is more fear around finasteride due to its higher prevalence and being the first line of defense, while dutasteride is less commonly prescribed and used by those who have already tried finasteride without side effects.

      community Got prescribed Dutasteride today

      in Treatment  13 upvotes 10 months ago
      The conversation is about someone being prescribed Dutasteride for hair loss. Specific treatments mentioned include Minoxidil, Finasteride, and RU58841.

      community Is getting on Dut at 21 a bad idea after taking Fin since 18?

      in Chat  7 upvotes 6 months ago
      A user is considering switching from finasteride to dutasteride for hair loss at age 21, worried about potential side effects on bone and brain development. Another user shared their positive experience with dutasteride, noting minimal body hair and no side effects.

      community How to use thickening hair products?

      in Styling  13 upvotes 2 years ago
      User asks for advice on using hair thickening products and their order of application. Experienced styler suggests using thickening tonic with a blow dryer, followed by styling powder and clay, then hair fibers, and finishing with hairspray.

      community Dr. Gabel Doesn't Use Verteporfin

      in Transplants  3 upvotes 3 months ago
      Dr. Gabel doesn't use Verteporfin because it's not FDA approved. The user is getting FUT and wants to minimize scarring and maximize hair regrowth.

      community Treating MPB while dealing with seborrheic dermatitis?

      in Treatment  8 upvotes 5 months ago
      The user is seeking advice on treating male pattern baldness (MPB) while dealing with seborrheic dermatitis, specifically asking about the use of finasteride (Fin) and minoxidil (Min). They are concerned about side effects and are looking for recommendations to improve overall hair thickness, especially on the crown.

      community Dutasteride/finasteride theory

      in Finasteride/Dutasteride  5 upvotes 6 months ago
      Finasteride worked better for frontal scalp hair loss, while dutasteride helped the crown and mid-scalp but worsened the frontal area. The user shared personal experiences and invited open dialogue.

      community Finasteride 1 mg daily vs Dutasteride 0.5 mg daily

      in Treatment  10 upvotes 8 months ago
      Switching from finasteride 1mg daily to dutasteride 0.5mg daily may offer better hair regrowth. However, if finasteride is effective, fully switching to dutasteride is not advised; instead, adding dutasteride once a week could be beneficial.

      community How Do You Get A Dut Prescription?

      in Finasteride/Dutasteride  14 upvotes 10 months ago
      A user considering switching from finasteride to dutasteride for hair loss is seeking advice on how to get a prescription, with suggestions to ask their primary care physician or consult a dermatologist, and mentions of telehealth options for obtaining the prescription.

      community What the hell does it mean by “do not apply to front of scalp”

      in Minoxidil  20 upvotes 3 weeks ago
      Minoxidil can be applied to the entire scalp, including the hairline, despite labels suggesting otherwise due to lack of specific testing. For best results in treating hair loss, combining minoxidil with finasteride is recommended, as finasteride addresses the underlying cause of male pattern baldness.

      community Questions about Topical Finasteride and more

      in Finasteride/Dutasteride  7 upvotes 1 month ago
      The conversation discusses using topical finasteride (0.25% gel) and minoxidil (5% foam) for hair loss, with users sharing experiences about application methods, microneedling, and results. Some users have switched to oral finasteride for convenience and cost-effectiveness, while others discuss the greasy nature of the topical solution.

      community 2.5mg minoxidil and 1mg finasteride 1caps daily

      in Chat  1 upvotes 2 months ago
      The conversation discusses using 2.5mg minoxidil and 1mg finasteride capsules daily for hair loss, with the addition of Nizoral shampoo for dandruff. It suggests switching to Selsun Blue if Nizoral worsens the condition.

      community Best place to get topical dutasteride?

      in Finasteride/Dutasteride  2 upvotes 2 months ago
      The user has been using finasteride and topical minoxidil for hair loss but hasn't seen significant regrowth. They are considering adding topical dutasteride and are exploring options like Happy Head for this treatment.

      community Why is everyone not directly advised Dutasteride?

      in Finasteride/Dutasteride  163 upvotes 2 months ago
      Dutasteride is less commonly prescribed for hair loss because it is not FDA-approved for this purpose, unlike finasteride, which is more accessible and preferred due to fewer side effects. Dutasteride may be more effective in reducing DHT but has a longer half-life and potentially more significant side effects.

      community Which retinoid for better min absorption?

      in Product  4 upvotes 3 months ago
      User is on vacation in Greece and wants to buy tretinoin or isotretinoin to improve Minoxidil absorption. They are considering isotretinoin since it is available over-the-counter in Greece but requires a prescription back home.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 4 months ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community Shampoo recommendations for dandruff removal.

      in Treatment  3 upvotes 4 months ago
      The user experiences increased dandruff from daily use of minoxidil and finasteride, and seeks shampoo recommendations for an oily scalp that can address dandruff and aid hair restoration. They found Anaphase and an Indian herbal shampoo ineffective.

      community What is the best legit source of RU58841 in the UK?

      in Product  6 upvotes 4 months ago
      A user is seeking a trusted supplier for RU58841 in the UK, expressing doubts about their current source, rudirect, and considering Anagenic and receptorchem. They are asking for recommendations for other suppliers.

      community 1 Year Fin then 6 Months Dut - No Success

      in Finasteride/Dutasteride  4 upvotes 4 months ago
      The user saw no improvement in hair loss after using Finasteride for a year and Dutasteride for six months. They also experienced scalp inflammation and tried various treatments like Ketoconazole and Salicylic Acid without success.