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GlossaryInner Root Sheath (IRS)

layer of cells supporting and shaping the growing hair shaft

The Inner Root Sheath (IRS) is a layer of cells that surrounds and supports the growing hair shaft within the hair follicle. It plays a crucial role in shaping the hair and guiding it as it emerges from the scalp. The IRS is composed of three distinct layers: Henle's layer, Huxley's layer, and the cuticle of the inner root sheath, each contributing to the structural integrity and function of the hair follicle.

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community Any news on potential hair loss treatments?

in Research/Science 13 upvotes 11 months ago

The conversation is about seeking updates on new hair loss treatments, specifically mentioning scube3 and GT20029, with one person mentioning HMI_115 as showing promising results.

community Doing sulforaphane since 2 weeks got new babyhairs

in Product 11 upvotes 3 years ago

The user noticed new baby hairs after using sulforaphane but is still experiencing shedding. They are seeking a supplement to stop shedding, possibly grape seed extract.

community 22 Years Old, 4 Months Of Minoxidil.

in Update 670 upvotes 4 years ago

The user's experience using Minoxidil to treat hair loss, with discussion of Finasteride and RU58841 as additional treatments. Additional advice is provided on ketozolin shampoo use and microdosing finasteride.

community 2 years of fin, 1.5 years of minoxidil, calling it quits. Thank you.

in Shaved/buzzed 567 upvotes 1 year ago

This user has been struggling with hair loss for the past two years and attempted to treat it using finasteride and minoxidil. Despite their efforts, they have not seen any improvement in their condition, so they have decided to shave or buzz their head instead. Others gave advice on other treatments that could be tried if desired.

community to all people who cannot tolerate anti androgens (loe dose topical fin, pyrilutamide, CB) i am getting desperate, looking for a solution

in Research/Science 13 upvotes 1 year ago

The user tried Minoxidil without success, and Finasteride worked but caused sexual side effects even at a very low dose. They are seeking alternative treatments for hair loss as they cannot tolerate anti-androgens and are also in therapy for mental health.

community New potential hair loss treatment (news release)

in Treatment 186 upvotes 4 years ago

New potential hair loss treatment uses molecules from hairy moles to stimulate follicle growth. Topical solution requires less frequent application, like Botox injections a few times per year.

community What is this pigmentation around my follicles?

in Chat 29 upvotes 2 weeks ago

The conversation discusses potential causes of pigmentation around hair follicles, suggesting sebum buildup, autoimmune conditions, or dermatitis. Treatments mentioned include finasteride, dutasteride, and an anti-inflammatory diet, with a recommendation to consult a doctor for a proper diagnosis.

community Check out this shed-topical finasteride/topical minoxidil

in Progress Pictures 253 upvotes 2 years ago

This conversation is about a user who has been using topical finasteride and minoxidil to treat their hair loss, with the result being an intense shedding period. Other users have offered advice and encouragement for them to keep going with the treatment, suggesting they may see significant regrowth in 6 months time.