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      community Pyrilutamide stopping Minoxidil gains

      in Chat  2 upvotes 10 months ago
      Pyrilutamide is seen as effective for maintaining hair without regrowth, while Minoxidil is known for growing new hair but causes shedding of old hairs. There is a question if using Pyrilutamide would inhibit the hair regrowth effects of Minoxidil.

      community Fats on your Head to Stop Hair Loss?

      in Research/Science  140 upvotes 1 year ago
      The conversation discusses the potential of long-chain unsaturated fatty acids, like oleic and linoleic acid, as an additional treatment for hair loss, which may inhibit the enzyme responsible for converting testosterone to DHT and promote hair growth. Users humorously suggest using oils topically and discuss other hair loss treatments, but the main focus is on the science behind fatty acids and their role in hair health.

      community Verteporfin day 119 update - donor hair regeneration human trial

      in Research/Science  146 upvotes 2 years ago
      A human trial of verteporfin, a drug that can inhibit wound healing by scarring and promote regeneration of original tissue and hair follicles to provide an unlimited source for hair transplants; people discussed the potential of this drug and how it could be rolled out in mainstream with more doctors getting on board.

      community Last resort attempt. Studies suggest that finasteride topically actually inhibits up to 52% scalp dht which is smiles to dut 0.5mg daily. This solution contains: fin, min, melatonin and progesterone. Trial started today.

      in Research/Science  8 upvotes 2 years ago
      The conversation discusses a last-resort hair loss treatment combining topical finasteride, minoxidil, melatonin, and progesterone, with claims that topical finasteride can inhibit up to 52% of scalp DHT. One reply clarifies that progesterone is not an anti-androgen but has anti-androgenic properties because it competes with androgens for receptors.

      community Oral Minoxidil and Grapefruit Juice

      in Research/Science  96 upvotes 1 year ago
      The conversation is about the potential dangers of taking oral minoxidil and grapefruit juice together. Some users express concern about dangerous drug interactions, while others argue that grapefruit juice may inhibit the metabolism of finasteride. The conclusion is that grapefruit juice may make finasteride less effective, but it won't affect minoxidil.

      community Similar 5ar inhibitors to fin?

      in Finasteride/Dutasteride 3 years ago
      Natural vitamins like pumpkin seed oil, saw palmetto, and ecklonia cava are discussed for their potential to lower DHT levels. They may work similarly to finasteride but are significantly weaker.

      community We need actual hair loss studies on Epristeride

      in Research/Science  6 upvotes 4 months ago
      Epristeride is a selective 5 alpha reductase type 2 inhibitor that may reduce scalp DHT similarly to finasteride, with potentially fewer side effects. It is suggested that combining epristeride with finasteride or dutasteride could enhance hair loss treatment effectiveness.

      community Microneedling - 6 months and no results. Any advice?

      in Treatment  10 upvotes 3 years ago
      Microneedling for 6 months with minoxidil showed no improvements in hair growth. User seeks advice on other treatments or whether to continue microneedling; current stack includes finasteride, eucapil, and minoxidil with tretinoin.

      community Dustaride and vitamins question?

      in Finasteride/Dutasteride  3 upvotes 4 months ago
      Dustaride doesn't require avoiding any vitamins, but checking vitamin D levels and supplementing if deficient is suggested. Hair vitamins are generally unnecessary unless there's a deficiency.

      community Best Treatment In The Pipeline?

      in Chat  15 upvotes 7 months ago
      New treatments for AGA are emerging, including pyrilutumide, gt0029, scube3, kx-826, and pp405. Verteporfin is mentioned as a promising option.

      community Low-dose oral minoxidil and skin aging

      in Minoxidil  7 upvotes 6 years ago
      The conversation discusses the use of low-dose oral minoxidil for hair loss and its potential effects on skin aging. Users shared experiences, with some noting side effects like puffy eyelids and dark circles, but no conclusive evidence of significant collagen depletion or increased wrinkles.

      community Winlevi coming out in 2019

       15 upvotes 6 years ago
      The conversation discusses the potential release of Winlevi in 2019 by Cassiopeia for hair loss treatment. It suggests a regimen combining minoxidil, Winlevi, Nizoral, and possibly dermarolling, with a comment mentioning Breezula as an alternative to finasteride without side effects.

      community Anyone have success with fenugreek?

      in Technology  10 upvotes 4 years ago
      Fenugreek has mixed reviews for hair loss, with some reporting success and others experiencing worsening conditions. Few people have shared their experiences online.

      community Diagnosed with MPB. Started with finastride 1mg

      in Finasteride/Dutasteride  18 upvotes 1 year ago
      A 28-year-old male diagnosed with Male Pattern Baldness is using finasteride 1mg and asking if it's sufficient without minoxidil, PRP, or multivitamins. The advice given is to continue with finasteride and assess results after a year before considering additional treatments.

      community Goodbye y'all, it's been a journey but have accepted where I'm at

      in Update  219 upvotes 1 year ago
      The conclusion of this conversation about hair loss is that the user, y00sh420, tried various treatments including a $700 lllt helmet, topical minoxidil and finasteride, spectraDNC, and micro needling, but did not achieve the desired results. They have decided to stop trying until a cure for male pattern baldness is found. Other users expressed different opinions on hair loss treatments.

      community The ultimate regiment to reverse hairloss

      in Treatment  6 upvotes 2 years ago
      The conclusion of the conversation is that the user "Shakalakaplaka" shares their comprehensive hair loss regimen, which includes various treatments targeting different pathways such as DHT, inflammation, fibrosis, immune system, testosterone, gut problems, and scalp health. The effectiveness of the regimen is not confirmed, and some users express skepticism or request before and after pictures for credibility.

      community What do we actually know about HMI-115?

      in Chat  16 upvotes 1 year ago
      The post and conversation are about HMI-115, a potential treatment for hair loss. The conclusion is that HMI-115 is not a 5ar-inhibitor and is instead a prolactin receptor inhibitor. Some users are skeptical about its effectiveness and believe that baldness will still be a problem in the future.

      community Best all in one supplement for hair health

      in Treatment  14 upvotes 4 years ago
      The conversation is about supplements for hair health. Nutrafol and Viviscal are mentioned, with Nutrafol preferred due to saw palmetto; individual supplements like zinc, vitamin D, iron, B complex, magnesium, and inositol are also discussed.

      community What's "wrong" with oral minoxidil, exactly?

      in Minoxidil  173 upvotes 4 months ago
      Oral minoxidil can boost hair growth but may cause side effects like heart palpitations and increased body hair. Many prefer topical minoxidil due to fewer side effects.

      community Blood work after one year of fin/dut

      in Finasteride/Dutasteride  7 upvotes 2 years ago
      After using finasteride and dutasteride for hair loss, a user's blood tests showed almost unchanged DHT levels and some out-of-range hormone levels. They experienced side effects when taking dutasteride daily and also take supplements that boost testosterone.

      community 19M Am i a minoxidil hyper responder?

      in Progress Pictures  52 upvotes 8 months ago
      A 19-year-old using topical minoxidil and dutasteride reports significant hair growth and shedding. Minoxidil caused new facial hair growth, and the user hopes for thicker hair regrowth.

      community what do you think about Ell-Cranell + Quercetin

      in Treatment  6 upvotes 1 year ago
      The post discusses the use of El-Cranell, which contains Alfatradiol, and Quercetin as a treatment for hair loss. The user is seeking recommendations on the amount of Quercetin to add to the solution. The conclusion of the document is that Quercetin has been shown to stimulate hair growth and inhibit DHT, and combining it with zinc/copper may have a synergistic effect.

      community Tretinoin every other day? (with daily minoxidil)

      in Minoxidil  1 upvotes 4 months ago
      The user is considering using Tretinoin every other day alongside daily Minoxidil to manage hair loss and is concerned about inconsistent absorption affecting regrowth. They have noticed a significant reduction in shedding but are unsure if it's due to Tretinoin or the end of the Minoxidil/finasteride shedding phase.

      community Ultimate Hairloss Flowchart (for beginners)

      in Treatment  247 upvotes 1 year ago
      The conversation discusses a hair loss flowchart for beginners, with mixed opinions on its effectiveness. Treatments mentioned include minoxidil, finasteride, dutasteride, microneedling, and vitamins.

      community Tretinoin every other day? (with daily minoxidil)

      in Minoxidil  3 upvotes 4 months ago
      Using Tretinoin every other day with daily Minoxidil may help with hair regrowth, and some users find it more effective than daily use. There are concerns about irritation and absorption, but small amounts seem to minimize harm.

      community FDA approves Cassiopea's WINLEVI (CB-03-01, 1% formulation) for Acne

      in Technology  32 upvotes 4 years ago
      The conversation is about the FDA approval of WINLEVI for acne treatment and the anticipation of Breezula, a hair loss treatment using the same active ingredient, which may indicate a positive future for Breezula's release. There is disappointment that Breezula's results are not optimal, but it is seen as progress in hair loss treatment.