TWIST-1 gene's role in hair loss and potential as a treatment target. Inhibiting TWIST-1 may prolong hair growth and reduce hair follicle sensitivity to DHT.
Hair loss can be treated by correcting glucose metabolism in hair follicles and using equol as a safer DHT blocker. Production of these treatments is starting soon, and a Discord channel is available for more information.
Finasteride can cause sexual side effects in less than 2% of men, but these often disappear over time, even if the treatment continues. Some users report persistent side effects, while others experience no issues or only temporary ones.
Kintor Pharma successfully dosed the first patient in a Phase II trial for KX-826 for acne vulgaris. Users are more interested in results for male pattern baldness (MPB).
User experienced significant hair growth in 3 months using finasteride, minoxidil, microneedling, and scalp massages. Others questioned the authenticity of the results due to the rapid progress.
The user has seen improvement in their hair loss after 6.5 months on finasteride, 8 months on Minoxidil and RU58841, and using Nizoral twice a week. Commenters suggest adding microneedling to the treatment regimen for potentially better results.
The conversation is about the delay in Breezula's phase 3 trials and skepticism regarding its effectiveness compared to other treatments like RU58841 and Pyrilutamide. Some users prefer safety over effectiveness, while others express frustration with the slow progress and doubt Breezula will be a significant treatment for hair loss.
The conversation discusses using T3 (triiodothyronine) as a topical treatment for hair growth, with some users noting it showed promising results in studies but lacked follow-up. Users express interest in trying T3 due to its potential effectiveness compared to Minoxidil.
The conversation is about using stemoxydine in addition to minoxidil for hair growth. The original poster is considering adding stemoxydine to their hair loss treatment regimen.
The user experienced almost no improvement in hair loss after 3 months using microneedling, RU58841, sulforaphane, finasteride, and dutasteride, especially after stopping minoxidil. They believe minoxidil is more effective than RU58841.
User wants to try procyanidin b2 and broccoli sprouts sulforaphane for hair loss and asks for supplement suggestions. Replies suggest taking fin by asteride and growing sprouts in mason jars to eat raw.
The conversation discusses the difficulty in distinguishing between side effects of finasteride (like brain fog and loss of libido) and depression caused by hair loss. Users share experiences of severe depression while on finasteride, leading some to stop the treatment despite anxiety over hair loss.
A user was frustrated with delays in getting finasteride for hair loss, was prescribed minoxidil, and found a vitamin B7 deficiency. They are questioning if the deficiency could cause receded temples and considering finding a new dermatologist.
Eli Lilly's drug baricitinib showed effectiveness in treating alopecia areata, with higher doses resulting in significant hair regrowth compared to placebo. The treatment is not for male pattern baldness.
Hair loss treatments discussed include leave-in conditioner, volumizing powder, styling products, and hairspray for thicker appearance without fibers. User shares routine and product suggestions for people with thin hair that lacks volume.
User started hair loss treatment in November 2020 using Finasteride, Minoxidil, Dermaroller, castor oil, Nizoral, and supplements. They experienced improvements but had a second shed in February and seek feedback on their routine.
The conversation discusses the variability in effectiveness and safety of generic finasteride from different manufacturers, with some generics potentially containing impurities. Users shared their experiences with various brands, questioning if different brands affect hair loss treatment outcomes.
Breezula passed a clinical trial in August and there are questions about its availability in 2021 and potential delays due to Covid. No specific treatments were discussed.
A user shared their 115-day progress in treating hair loss using 5% Minoxidil, topical Finasteride, biotin, microneedling, and collagen peptides. They reported visible improvement and no side effects from topical Finasteride, unlike the oral form.
Microneedling may help regrow hair in dormant bald regions by stimulating stem cell transfer. Users discuss its effectiveness and how collagen might aid in the process.
A user who underwent a hair transplant in Istanbul to reduce balding, and the discussion of various treatments such as finasteride and growth hormone for preventing further hair loss.
Accepting hair loss and not taking drastic measures like shaving your head if you are only mildly balding, and encouraging people to fight it with treatments such as finasteride, minoxidil, nizoral and microneedling. Additionally, it discusses the importance of being realistic when trying to restore hair and addressing the misconception that one must look a certain way in order to be attractive.
Pumpkin seed oil showed a 40% increase in hair count, but its effectiveness is questioned due to other ingredients in the supplement. Users discuss its potential compared to finasteride, with some expressing skepticism and others showing interest.
Hair loss discussion includes delay in others noticing balding, using hair fibers for peace of mind, and taking before and after photos. Finasteride and Minoxidil are mentioned as treatments.
The user started using 5% minoxidil foam in February and experienced shedding a few weeks later, which continued for about twelve weeks. They are also taking pumpkin seed oil and saw palmetto but remain skeptical about their effectiveness.
The conversation discusses the role of DHT in male hair loss and the effectiveness of treatments like Finasteride, which reduces DHT, and RU58841, which blocks DHT from binding to scalp receptors. The user debates the trade-offs between maintaining hair and having a healthy endocrine system, suggesting RU58841 might allow for both.
The post and conversation are about a user's 3-month progress using Minoxidil, Finasteride, Nizoral shampoo, and derma-rolling for hair loss. The user reports noticeable improvement in their hairline.
The user experienced no improvement in hair loss with finasteride and minoxidil but had side effects. They plan to add wounding, scalp massage, vitamin K, and taurine supplements to their regimen and seek feedback on these additions.