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A user is participating in a phase 3 trial for Clascoterone, a topical acne medication that may stimulate hair growth, and will share results after 6 months. They will have a section of their hair shaved and marked with a tattoo for the study.

A user shared a 9-month update on hair loss treatment, reporting positive results from taking 1 mg of finasteride and 1.25 mg of minoxidil daily. The discussion includes varied experiences with these treatments, questions about side effects, and comments on the unpredictability of treatment effectiveness.

A user who had success with finasteride for hair loss for 4-5 years experienced shedding after a 3-week break. They tried various treatments including different finasteride brands, dutasteride, topical treatments, and supplements, but are still facing hair loss.

A user asked if collagen or hair growth supplements made their hair thicker. Another user suggested that Vitamin D might help if deficient.

Testosterone within the normal range does not significantly contribute to male pattern baldness (MPB); DHT is the main factor that can be controlled. Genetics play a crucial role in hair loss, and treatments like finasteride and dutasteride, which block DHT, can help despite potentially raising testosterone levels.

User shared 3.5 months of hair regrowth progress using oral minoxidil 2.5 mg and microneedling, noting a younger appearance. Replies included congratulations and comments on the impressive results.

The conversation discusses various factors affecting hair loss, not just DHT, and mentions treatments like Minoxidil, finasteride, and melatonin. Some users report personal experiences with these treatments and hormone tests, while others speculate on the role of hormones like prolactin and cortisol in hair loss.

Hair loss caused insecurity and affected social life for a 21-year-old. Failed hair transplant led to mental breakdown and struggle with studies.

The effects of Pyrilutamide, a hair loss treatment that is being tested for June/July; and reports from people who have experienced side effects similar to those of RU58841, suggesting they may have been sold an incorrect product from their supplier.

User discovered hair fibers (Toppik) for covering bald spots and recommends it. Others agree it's a game changer and boosts confidence.

The conversation discusses CRISPR-on & CRISPR-off as a potential cure for baldness, contrasting it with hair cloning and other treatments like Minoxidil, finasteride, and RU58841. It also mentions the potential of mRNA for gene expression control and the prioritization of gene editing for severe genetic conditions.

A user found that taking Zyrtec (Cetirizine) and Advil helped reduce their scalp inflammation and pain, potentially creating a better environment for hair growth. They have not used any other medication for hair loss or scalp issues.

The user shared a 1-year update on using finasteride (0.25mg three times a week), biotin, ketoconazole shampoo, and vitamin D for hair loss, showing positive results with pictures and no side effects. Other users commented on the effectiveness and the user's good response to the treatment.

Many people use finasteride and dutasteride for hair loss, with some switching due to cost or effectiveness. Minoxidil is also commonly used, and side effects like weaker erections or ball pain are reported by some.

Switching from finasteride to dutasteride may be more effective for hair regrowth due to dutasteride's stronger enzyme inhibition, but combining both drugs could enhance results. Some users report better outcomes with dutasteride, while others recommend a gradual transition to prevent potential hair loss.

Switching from topical to oral minoxidil due to scalp irritation and unsatisfactory results, while also seeking cheaper options in the U.S. Oral minoxidil is generally favored for its effectiveness and fewer application downsides, with CostPlusDrugs and GoodRx offering affordable prices.

KX-826 initially improves hair growth but declines after 24 weeks, with mild itching as a side effect. Combining it with minoxidil and finasteride may improve results, but long-term effectiveness is uncertain.

There have been no new effective hair loss treatments since finasteride, despite technological advancements. Current treatments include finasteride, minoxidil, and RU58841, with ongoing challenges and potential future solutions in research.

Hair loss progress pictures can be misleading due to differences in lighting, hair length, and wetness, making it hard to accurately assess changes. Treatments mentioned include minoxidil and finasteride, with some users expressing skepticism about their effectiveness.

Participants want to maintain hair until at least age 30, using treatments like finasteride, dutasteride, and minoxidil. Hair loss remains a concern, with some considering hair transplants.

A user encouraged others experiencing hair loss to try shaving their heads, sharing their own positive experience despite briefly using finasteride and natural methods. Responses were mixed, with some supporting the decision and others suggesting treatments like minoxidil and finasteride, while many commented on the appearance changes.

A user experienced significant hair shedding and thinning 10 months post-hair transplant despite using minoxidil and topical finasteride. They are considering switching to oral finasteride or dutasteride and are also dealing with scalp conditions like seborrheic dermatitis.

RU58841, a potential hair loss treatment, was not commercialized due to marketability issues and lack of long-term safety data. Concerns about its formulation and delivery methods further complicate its use.

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

A 23-year-old experiencing diffuse hair thinning has chosen a treatment stack including topical finasteride, a blend of rosemary, peppermint, and pumpkin seed oils, procyanidine B2 spray, ketoconazole shampoo, and scalp massages. They avoid minoxidil due to family history of side effects and oral finasteride due to high estrogen levels.

User has seen no improvement after 4 years of using minoxidil and finasteride, and recently started dutasteride. Suggestions include adding oral minoxidil, microneedling, and considering a hair transplant.

Topical finasteride is considered a safer option for hair regrowth with fewer systemic side effects compared to oral finasteride. Some users report similar efficacy and side effects between topical and oral treatments, while others prefer topical due to reduced systemic exposure.

A user shared their experience with hair loss treatments, noting improvement after switching from minoxidil and finasteride to dutasteride. They observed new hair growth and reduced scalp inflammation, expressing hope for further progress.

Switching from finasteride to dutasteride and back to finasteride led to gynecomastia and fatigue, likely due to hormonal imbalances. Suggested treatments include Tamoxifen, Raloxifene, or low-dose Anastrozole, with a recommendation to test testosterone and estradiol levels.

A user shared 5 months of progress using 1mg finasteride and 2.5mg minoxidil, showing before and after pictures. Other users complimented the results and discussed their own experiences with similar treatments.