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      community Rosemary oil's potency as a dht blocker

      in Research/Science  65 upvotes 11 months ago
      Rosemary extract showed high inhibitory activity against DHT, similar to finasteride and dutasteride, but the conversation includes skepticism about its effectiveness in humans since the study was done on mice and rosemary oil is often considered ineffective based on personal experiences. Some suggest trying rosemary oil alongside other treatments, while others emphasize the difference between the extract used in the study and the oil.

      community Verterporfin combined with hairline lowering?

      in Technology  8 upvotes 11 months ago
      Verteporfin might be a potential cure for hair loss and could heal scars, which may lead to natural-looking results when combined with hairline lowering surgery. One person suggests waiting to see if verteporfin actually works as claimed.

      community Pyrilutamide phase III clinical trial results released

      in Research/Science  31 upvotes 11 months ago
      Pyrilutamide did not show effectiveness in regrowing hair compared to a placebo, but it may still help maintain existing hair by preventing DHT from causing follicle miniaturization. Some users believe it could be beneficial when used with other treatments like minoxidil, finasteride, and dutasteride.

      community why hair restoration has not been progressed for last 20 years?

      in Chat  34 upvotes 1 year ago
      The conversation discusses the lack of significant advancements in hair loss treatments beyond finasteride and minoxidil, questioning if hair restoration technology has reached a dead end. Hair transplant technology has improved, but new medications face challenges with market entry, cost, accessibility, and long-term effectiveness.

      community Vertoporfin research update by Dr Bloxham

      in Research/Science  71 upvotes 1 year ago
      The conversation discusses the potential of verteporfin in treating hair loss, with some users reporting positive results and speculating that it could lead to a cure for baldness. Others are skeptical, and there's a debate on the effectiveness of verteporfin for regrowing hair and reducing transplant scars.

      community Switched from finasteride to dutasteride - 2 month update

      in Finasteride/Dutasteride  6 upvotes 1 year ago
      The user switched from finasteride to dutasteride for hair loss treatment, but experienced increased libido, itchy scalp, and accelerated hair loss. Another user suggested that genetic variations might cause dutasteride to be less effective and recommended checking for specific genetic markers.

      community Minoxidil&Finasteride 7 months progress

      in Progress Pictures  936 upvotes 1 year ago
      A user shared their 7-month progress using Minoxidil and Finasteride for hair loss, which significantly reversed their aging appearance. They applied Minoxidil twice daily, took 1mg Finasteride once daily, micro-needled weekly, maintained a high protein diet with vitamins and biotin, and recommended a balanced lifestyle for best results.

      community Atherosclerosis as cause of balding and treatment

      in Treatment  61 upvotes 1 year ago
      Hair loss may be caused by calcification of capillaries in the scalp, restricting blood flow to hair follicles. A daily treatment regimen including high doses of Vitamins D and K, Magnesium, and Nattokinase could potentially decalcify these capillaries, improving blood flow and hair growth. However, some users warn against excessive Vitamin D intake and emphasize the need for medical consultation.

      community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

      in Research/Science  65 upvotes 1 year ago
      Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

      community Is this regrowth? 11 months topical solution (min/fin)

      in Is this regrowth?  417 upvotes 1 year ago
      The user has been using a topical solution of Minoxidil and Finasteride for hair regrowth for 11 months, applying it three times a week. The responses to the user's question about regrowth are mixed, with some users confirming regrowth and others suggesting it's time to give up.

      community my dermatologist prescribed me two shampoos and vitamins hair

      in Chat  18 upvotes 1 year ago
      A 21-year-old experiencing hair loss was prescribed two shampoos and hair vitamins by a dermatologist who suggested seborrheic dermatitis as the cause. However, users in the conversation suggested the hair loss could be male pattern baldness (MPB), recommending monitoring the situation and considering finasteride as a treatment.

      community CAUTION: My Experience with RU58841

      in Treatment  13 upvotes 1 year ago
      The user experienced concerning side effects like throat irritation, shortness of breath, chest pain, and testicle pain after using RU58841 for hair loss, despite also using finasteride and minoxidil. Other users shared mixed experiences, with one advising to stop using RU58841 due to similar side effects, while another reported significant hair loss reduction without side effects.

      community Why is no one pointing out dandruff as the number 1 evidence/symptom of MPB?

      in Chat  55 upvotes 1 year ago
      The post discusses the theory that persistent dandruff in areas prone to hair loss could be a sign of hair follicles dying due to DHT, indicating balding. The responses vary, with some users noting improvements in dandruff and hair loss with treatments like Dutasteride, while others experienced hair loss without dandruff.

      community Random thought that I don't think I have seen here yet. If Verteporfin is able to stop scar formation successfully in humans to a large degree (assuming future studies show this), wouldn't this basically open up the door for it being a no brainer for strong NW2s and 3s to opt for hairline lowering?

      in Research/Science  6 upvotes 1 year ago
      The conversation discusses the potential for Verteporfin to reduce scarring, making hairline lowering surgeries more viable for men with mild hair loss. The user suggests that if scarring can be minimized, men might opt for hairline lowering instead of using grafts for other areas.

      community Dry hair vs wet hair, is minox, microneedling and ketoconazole enough?

      in Treatment  110 upvotes 1 year ago
      The conclusion of the conversation is that using minoxidil, finasteride, and ketoconazole may not be enough to address hair loss caused by DHT. Some users recommend starting finasteride to prevent further hair loss, while others express concerns about potential side effects.

      community My 7 month oral minoxidil progress (1mg/day)

      in Progress Pictures  389 upvotes 1 year ago
      The conclusion of the conversation is that oral minoxidil has been effective in saving and restoring hair, but it may have diminishing returns as you age. It is suggested to consider using finasteride in addition to minoxidil for better results.

      community started RU58841 today and am panicing

      in Treatment  8 upvotes 1 year ago
      A user started using RU58841 for hair loss and experienced anxiety and physical discomfort. Other users suggested avoiding the treatment due to similar side effects and recommended alternative treatments like pyri.

      community What do we actually know about HMI-115?

      in Chat  16 upvotes 1 year ago
      The post and conversation are about HMI-115, a potential treatment for hair loss. The conclusion is that HMI-115 is not a 5ar-inhibitor and is instead a prolactin receptor inhibitor. Some users are skeptical about its effectiveness and believe that baldness will still be a problem in the future.

      community Is GT20029 supposed to regrow hair as well?

      in Treatment  10 upvotes 1 year ago
      The user is considering switching from finasteride to dutasteride for hair loss. They are unsure if GT20029 can regrow hair, particularly on the temples. Another user mentions that regrowth on finasteride can take up to 2 years.

      community Pyrilutamide for 16 weeks, with some progress

      in Progress Pictures  40 upvotes 1 year ago
      User gained hair with topical minoxidil and finasteride, then experienced shedding after starting pyrilutamide. After 12 weeks, new hairs grew and existing hairs thickened, hoping for more improvement in a year.

      community Minoxidil Response Test kit in the EU?

      in Minoxidil  2 upvotes 1 year ago
      A user is seeking a Minoxidil Response Test kit in the EU without bundled consultations. They mention alternatives like oral minoxidil and tretinoin but prefer the test alone.

      community Study: Peppermint oil more effective than minoxidil, thoughts?

      in Research/Science  14 upvotes 1 year ago
      The conversation discusses a claim that peppermint oil is more effective than minoxidil for hair loss, with one user mentioning using a mix of peppermint and rosemary oils as a treatment. Some users are skeptical, while others show interest in the potential of peppermint oil.