The conversation is about the struggles of dealing with diffuse thinning at a young age and the lack of significant improvement after using treatments like finasteride and minoxidil. Some suggest additional methods like derma rolling, microneedling, and hair fibers, while others share their own experiences and encourage persistence with treatment.
Some people respond better to minoxidil due to higher enzyme levels converting it to its active form. Minoxidil helps with hair regrowth but doesn't prevent hairloss; finasteride and other DHT inhibitors are needed for that.
Dutasteride takes 1-3 months to affect scalp DHT levels, not just a week. The prostate absorbs Dutasteride faster than the scalp due to different vascular networks and enzyme densities.
A user is considering using RU58841 for female pattern baldness and is also planning to use Minoxidil. They are hesitant to ask their doctor for spironolactone due to its cosmetic nature and are experiencing significant hairloss possibly due to stress and hormonal issues.
A 20-year-old experiencing hair shedding after starting oral finasteride is advised to continue treatment and consider adding topical minoxidil. Shedding is normal, and patience is needed for hair regrowth.
An 18-year-old male's successful hair regrowth after three months of using finasteride 1mg daily. He reported no side effects and other users expressed admiration and curiosity about his results.
A user's hair regrowth journey involved a hair transplant and using RU58841, finasteride, and minoxidil, with side effects managed by other medications.
The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.
The post and conversation are about the role of the enzyme 3alpha-hydroxysteroid reductase in hairloss and the potential of compounds like procyanidin B2 and sulforaphane to boost its activity for hair regrowth. Further research is needed to develop effective treatments based on this theory.
A 21-year-old MTF individual is experiencing rapid hair thinning and is currently on estradiol valerate. They are inquiring about the effectiveness of spironolactone for hairloss, despite being aware of its serious side effects.
Peppermint oil may be beneficial for hair growth, potentially outperforming minoxidil. Users discuss its effectiveness compared to other treatments like finasteride and RU58841.
Finasteride can aid hair regrowth but may cause side effects like depression and sexual dysfunction. Users discuss experiences with finasteride, minoxidil, and RU58841, highlighting varied responses and the importance of informed treatment choices.
A user started using RU58841 a month ago after using finasteride and minoxidil for nearly three years, hoping for hair regrowth at the temples. Other users suggest vitamin B supplements and microneedling to improve hair thickness, and one mentions the possibility of a hair transplant for the temples.
Pyrilutamide, a nonsteroidal antiandrogen drug under development for the potential treatment of androgenic alopecia. The conversation discusses its binding affinity to the androgen receptor and the timeline for possible availability after trials are completed in the United States and China.
Dutasteride is often preferred over Finasteride due to fewer side effects and better hair regrowth. Initial side effects like lowered libido may occur but typically diminish over time.
A user shared a nearly 3-year update on their hairline improvement using Minoxidil, Finasteride, Nizoral, and Dermarolling. Other users commented on the success and discussed their own experiences with similar treatments.
A user's two-year progress using 1mg of oral finasteride daily and twice daily application of 5% minoxidil solution for hairloss. The user experienced temporary side effects but is pleased with the results, and another user warns about the importance of consistent use for maintaining results.
The user shared their positive hair regrowth experience using saw palmetto tablets, 5% minoxidil spray, and a Derma Pen. The conversation debates the effectiveness of saw palmetto versus finasteride, with some advocating for natural treatments and others emphasizing the proven results of finasteride and minoxidil, often in combination with microneedling.
The conclusion of the conversation is that the user, Lead_Tasso, is expressing gratitude for the community's help in restoring their confidence in treating hairloss. They have been using finasteride (fin) and minoxidil (min) and have also been taking hair and nail vitamins.
A 23-year-old male shared his 6-month hair transformation using Dutasteride, oral Minoxidil, ketoconazole shampoo, vitamin D, gym, cardio, and dermastamping. He reported significant hair maintenance and no side effects.
Despite using 5% minoxidil, 0.1% finasteride, and other treatments like microneedling, MK-677, and Cialis, hairloss continues with high testosterone and DHT levels. Considering oral dutasteride but concerned about further increasing testosterone levels.
A user shared their 2-month hair growth progress using only Minoxidil, noting significant improvement and plans to continue despite a genetic predisposition to baldness. They apply Minoxidil twice daily, experienced a heat rash, and chose not to use Finasteride due to side effects.
A female user starting Spironolactone treatment for thinning hair, and others sharing their experiences with Minoxidil and oral/sublingual Minoxidil as treatments.
The conversation is about using natural DHT blockers like pumpkin seed oil and saw palmetto extract for hairloss. The user has been using minoxidil, derma rolling, vitamin D, and biotin but is considering finasteride next.
The user experienced significant hair regrowth after one year on male-to-female hormone replacement therapy (HRT) and nine months using minoxidil and finasteride. They noted a reduction in body hair and attributed much of the hair regrowth to the addition of minoxidil.
A 39 year old female who has been taking finasteride for 1.5 months and is experiencing side effects such as muscle and butt shrinkage, and weight loss despite still having tight clothing. The user is seeking advice from those with knowledge of bodybuilding and hormones to help figure out the issue.
A 28-year-old has been using finasteride for five years, which stopped further hairloss but did not regrow the hairline. Recently, they started oral minoxidil to potentially improve results.
Whether using both Fluridil and Alfatradiol together could be more effective than either one alone as a hairloss treatment, given their different mechanisms of action.
Poor diet and lifestyle contribute to male pattern baldness. Treatments like Minoxidil, dietary changes, and lifestyle adjustments may help slow hairloss.