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TWIST-1 gene's role in hair loss and potential as a treatment target. Inhibiting TWIST-1 may prolong hair growth and reduce hair follicle sensitivity to DHT.

A 24-year-old person who is worried about their hair loss after 14 months of taking finasteride and 11 months of minoxidil. Replies to the post suggested sticking with their current regimen, that shedding from one part may not be telogen effluvium, and that shedding is normal with these drugs and they should evaluate in two to three months.

A user's progress in treating their hair loss using Minoxidil, Finasteride, ketoconazole shampoo, microneedling, omega 3, D3 and Forcapil vitamins over the course of three months. Other users offered support and advice to the original poster.

A user's personal hair loss progress with treatments, including finasteride (1.25mg), minoxidil, needling, and Nizoral; and advice from other users on how to perform the needling correctly.

A user who shared progress pictures of their scalp using a microscope camera, demonstrating the difference between healthy and miniaturized hair. Various explanations for the cause of this were discussed, such as DHT build-up in scalp sebum causing an autoimmune response leading to inflammation and eventual hair loss, with some suggesting a do-it-yourself treatment involving adding ascorbic acid powder to shampoo.

The conversation discusses hair regrowth treatments, specifically using finasteride, minoxidil, and microneedling with the Derminator. Users report significant improvements, especially after adding microneedling to their routine.

A user's transformation from an accountant to a spartan with a full beard, discussing the potential of DUPA and alopecia areata, as well as treatments like vitamins, topicals, and natural treatments for potential regrowth.

A user named "bmbshell" who was dealing with hair loss and initially tried to fix it with a hair system before deciding to try finasteride, dutasteride, minoxidil, microneedling, and biotin supplements. They documented their progress over the past 1 year and 3 months, showing how effective these treatments were in regrowing their hair.

User shared 1-year progress using Finasteride, Minoxidil, and dermarolling with no side effects. Others discussed their experiences and asked questions about the treatments.

Vitamin C mixed with shampoo stopped shedding and promoted hair regrowth after 1.5 years. Both the person and their wife experienced significant hair loss reduction with this method.

Jericho1017 shared their hair regrowth results after nearly 3 years using 1mg finasteride and 10,000mcg biotin daily, with noticeable improvement after 1.5 years and no significant side effects except for watery semen. Some users suggested adding minoxidil and microneedling to improve results, but Jericho1017 is currently content with their progress and not looking to add more treatments.

A 21-year-old female shared her 4-month hair growth progress using Minoxidil 5%, finasteride 1mg, Theradome LLLT, Viviscal vitamins, and PRP treatments twice. Commenters praised her progress and discussed other treatments like microneedling, but she noted her dermatologist advised against it due to potential scalp damage.

User experienced gynecomastia from finasteride and found a solution using liposomal topical finasteride. This method minimizes side effects and is effective for hair loss treatment.

User experienced significant hair growth in 3 months using finasteride, minoxidil, microneedling, and scalp massages. Others questioned the authenticity of the results due to the rapid progress.

Hair loss treatments discussed include dermarolling, minoxidil, finasteride, and RU58841. Some users find dermarolling sad, while others mention the complexity of biological systems and limited research funding for hair loss.

The conversation discusses expectations for the release of Breezula, a new hair loss treatment, and compares it to existing treatments like finasteride. Some believe Breezula could be a game-changer due to fewer side effects, while others await more permanent solutions like hair follicle cloning.

The user has been using finasteride, dutasteride, and RU58841 for hair loss without success and feels extremely uncomfortable with their appearance, including being bald and short. They express deep unhappiness and social isolation. Suggestions from others include adopting stoicism, focusing on personal development, considering a hair system, improving fashion, working out, and seeking therapy for mental health.

User reports 3-month progress using Fin 0.5mg/day, 1x minox 5%, keto shampoo every 3 days, and microneedling 1.5mm a week. Others suggest shaving sides or trying shaved head look, while some discuss side effects and dosages.

User balding1337 shared their hair loss treatment success using Finasteride 1mg/day, Minoxidil 5% 2x/day, microneedling at 1.5mm, and Biotin+Multivitamins. Another user mentioned that microneedling with minoxidil is 3-4x more effective than minoxidil alone.

The conversation discusses RU58841, a compound for hair loss treatment, which was found to be effective in a 6-month trial but was not pursued due to financial issues or marketability concerns, not safety. Some users are considering crowdfunding to release the research data, while others discuss personal experiences and safety concerns with RU58841.

The post and conversation are about the role of the enzyme 3alpha-hydroxysteroid reductase in hair loss and the potential of compounds like procyanidin B2 and sulforaphane to boost its activity for hair regrowth. Further research is needed to develop effective treatments based on this theory.

User baldwarrior85 regrets not starting finasteride earlier to prevent hair loss. Others share their experiences, with some having side effects and others seeing positive results from the treatment.

User tried DIY Dutasteride Mesotherapy for hair loss due to unsatisfactory Finasteride results. Used mesotherapy injection gun and liquid dutasteride for better results and fewer side effects.

The emotional impact of hair loss and the risks associated with common treatments such as finasteride, dutasteride, minoxidil, RU58841, and Fluridil. People discussed their personal experiences with these treatments, including potential side effects and lowered fertility. Hair transplants were also mentioned as a possible solution.

Hair loss treatment using Fin, Minoxidil and RU58841 with discussion about potential side effects and the power of nocebo effect.

A 26 year old female dealing with hair loss who is considering treatments such as Spiro, minoxidil and finasteride. Other potential solutions mentioned are PRP treatment, a wig, and bio-identical estrogen combined with bica.

A user's progress with using Minoxidil, Finasteride and Dermarolling to treat hair loss; some of the replies included reports of side effects, encouragement and advice on lighting.

The conversation is about a person struggling with aggressive hair loss and feeling depressed, who has tried finasteride but is experiencing sexual side effects. Others suggest various treatments like reducing finasteride dosage, trying minoxidil, dermarolling, addressing health and hormonal issues, and accepting baldness.

Hair loss theory suggests imbalance between Vitamin D Receptor (VDR) and Androgen Receptor (AR) activation. Proposed treatment includes upregulating VDR, downregulating AR, and improving mitochondrial health.

28-year-old struggles with aggressive hair loss since 18, used minoxidil with limited success. Tried hair systems but found them expensive, shaved head for job interviews but plans to return to hair systems.