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      community any news about DUPA (Diffuse unpatterned alopecia)?

      in Research/Science  10 upvotes 1 year ago
      The conversation discusses diffuse unpatterned alopecia (DUPA) and its possible causes, including sensitivity to DHT, not being androgenic alopecia, being diffuse alopecia areata, or hormonal issues. Treatments mentioned include topical melatonin, Clobetasol Propionate for alopecia areata, and the lack of results from using finasteride, dutasteride, and minoxidil.
      Topical Dutasteride - Non-Hormonal, Side Effect Free 5ARI?

      community Topical Dutasteride - Non-Hormonal, Side Effect Free 5ARI?

      in Treatments  372 upvotes 2 months ago
      Topical dutasteride is suggested as a low side-effect treatment for hair loss, with a proposed dose of 0.025% 1ml/day. It is considered better than finasteride due to its even inhibition of DHT isoforms and lower systemic absorption.

      community Adrogens and Covid-19

      in Treatment  8 upvotes 4 years ago
      The possible increased risk of severe Covid-19 cases in men due to higher androgen levels, and how taking medications such as finasteride, dutasteride, spironolactone, enzalutamide, or canabidiol might help mitigate the severity of the disease.

      community DHT/Testosterone levels in scalp Fin VS Dut.

      in Finasteride/Dutasteride  60 upvotes 3 months ago
      Dutasteride raises scalp testosterone by 99%, which may not be ideal for those sensitive to all androgens. Some argue finasteride's balancing act might be better, while others believe dutasteride is superior for hair regrowth.

      community Why does finasteride stop working?

      in Finasteride/Dutasteride  25 upvotes 2 weeks ago
      Finasteride may seem less effective over time due to increased DHT sensitivity or aging, but it still suppresses DHT. Switching to dutasteride offers stronger DHT suppression but may increase estrogen levels.

      community Having androgen receptor density and sensitivity at wrong f*ing place

      in Satire  7 upvotes 3 weeks ago
      The conversation discusses hair loss treatments, focusing on the use of topical minoxidil, microneedling, finasteride, and dutasteride, while debating the role of testosterone and DHT in hair loss. It also touches on the potential liver health impacts of these treatments and the genetic sensitivity of hair follicles to androgens.

      community Bloodwork reports just came in

      in Update  23 upvotes 11 months ago
      A 21-year-old male suffering from male pattern baldness is using topical finasteride and minoxidil, and oral minoxidil. His bloodwork shows normal DHT levels and slightly high testosterone, leading to discussions about the role of DHT sensitivity in hair loss, the potential impact of finasteride on his DHT levels, and the suggestion to proceed with oral finasteride due to his high testosterone.

      community M22 1 year 4 months topical min + oral fin

      in Finasteride/Dutasteride  216 upvotes 1 year ago
      A user's experience with hair loss treatments, specifically Minoxidil (topical) and Finasteride (oral), over a period of 1 year and 4 months. The user reported best results after 6 months, a significant hair shed 4 months ago, and current regrowth, while also using a 1.25mm dermastamp. The user adjusted Finasteride dosage over time and experienced high testosterone and nipple sensitivity.

      community Topical minoxidil and Body hair

      in Minoxidil  6 upvotes 1 year ago
      Topical minoxidil can cause increased body hair due to systemic absorption, varying by individual skin sensitivity. The user seeks experiences and solutions to prevent this side effect.

      community P5P supplementation for fin sides.

      in Treatment  7 upvotes 2 years ago
      P5P supplementation helped reverse finasteride side effects, particularly by lowering prolactin levels and restoring sensitivity. The user experienced significant improvement within a day and full recovery in a few days.

      community Hair loss causes are still a myth.

      in Chat  16 upvotes 2 years ago
      The conversation discusses the complexity of hair loss causes, suggesting that DHT sensitivity alone doesn't fully explain it. Treatments mentioned include finasteride and dutasteride.

      community Testosterone and Androgenetic Alopecia

      in Chat  8 upvotes 3 years ago
      How androgens, including testosterone, can cause hair follicles to miniaturize in people with sensitivity to androgens, and treatments such as finasteride, dutasteride, minoxidil, RU58841, or fluridil may be used in combination for long-term treatment.

      community If dutesteride and oral minoxidil doesn’t work that’s it right?

      in Treatment  20 upvotes 5 months ago
      A user is experiencing continued hair loss despite using 0.5mg dutasteride and 2.5mg minoxidil, and is seeking advice on why the treatments aren't working and how to address potential androgen receptor sensitivity. Replies suggest getting tested and considering scalp micropigmentation (SMP).

      community Tretinoin can make it worse!!!

      in Chat  7 upvotes 1 year ago
      Tretinoin may enhance minoxidil's effectiveness for those not responding to minoxidil alone, but it could reduce efficacy for some who are already responding to minoxidil. Tretinoin requires careful use, including skin moisturizing and sun protection due to increased sensitivity.

      community 3 months progress. Taking 0.5mg fin every other day. Naz shampoo twice weekly. Taking vitamin D and omega 3 daily.

      in Progress Pictures  167 upvotes 3 years ago
      A user shared a 3-month hair loss treatment progress using 0.5mg finasteride every other day, Naz shampoo twice weekly, and daily vitamin D and omega 3, without using minoxidil or dermarolling due to scalp sensitivity. Commenters noted the significant results from a low dose of finasteride and questioned the role of vitamins in the treatment.

      community Rosemary oil, peppermint oil, mucuna pruriens - two weeks in

      in Treatment  84 upvotes 1 year ago
      A user who is trying alternative treatments, such as mucuna pruriens dissolved in water/alcohol and a blend of jojoba oil, rosemary oil, and peppermint oil, for hair loss. Other users have shared anecdotal evidence, discussed the potential effectiveness of certain treatments, and questioned the time sensitivity of experimenting with new treatments.

      community Dim: high estradiol levels what to do

      in Chat  8 upvotes 3 months ago
      A user is experiencing facial bloating from low-dose topical finasteride due to high estradiol levels and is seeking advice on using DIM to manage this issue, including dosage and brand recommendations.

      community Dutasteride High Libido. How come we don't talk about this?

      in Finasteride/Dutasteride  206 upvotes 3 weeks ago
      Dutasteride and finasteride can affect libido differently, with some experiencing increased libido and others decreased libido or erectile dysfunction. Dutasteride may increase testosterone levels but can also cause side effects like liver enzyme changes, while topical finasteride may have fewer sexual side effects.

      community Bloodwork after 8 months on finasteride, is this normal?

      in Update  28 upvotes 6 months ago
      A user on finasteride for 8 months shared bloodwork results showing increased testosterone and estradiol levels, with concerns about high LH. Responses advised monitoring for symptoms but noted levels are within reference ranges.

      community Pyrilutamide just launched internationally, and all you're doing is hating

      in Product 2 months ago
      The post and conversation are about the high cost and skepticism surrounding pyrilutamide as a hair loss treatment, with comparisons to minoxidil, finasteride, and RU58841. The original poster defends pyrilutamide's effectiveness and criticizes others for dismissing it without proper understanding.

      community What's the deal with Zinc and DHT?

      in Chat  47 upvotes 5 months ago
      The conversation discusses the conflicting information about Zinc's effect on DHT and its role in hair loss. It mentions that Zinc can act as a 5AR inhibitor at high doses but may increase DHT if taken to correct a deficiency, and highlights the importance of nutritional balance for hair health.

      community Going to try and reverse MPB naturally.

      in Treatment  55 upvotes 2 years ago
      A user is trying to reverse male pattern baldness (MPB) naturally by taking high doses of Vitamin D, improving diet, exercising, reducing stress, and other lifestyle changes, but plans to use finasteride if no results are seen in 60 days. Other users are skeptical, advising medical treatments like finasteride and warning against potential vitamin D overdose and the ineffectiveness of natural remedies for genetic hair loss.