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      community Kintor Pharmaceutical Announces AR-PROTAC (GT20029) Approved for Acne and Androgenic Alopecia Clinical Trials in China

      in Technology  15 upvotes 3 years ago
      The conversation discusses the approval of Kintor Pharmaceutical's AR-PROTAC (GT20029) for clinical trials in China for acne and androgenic alopecia. One user expresses optimism about new treatments being developed and seeks clarification on how the new drug works, specifically if it temporarily degrades the AR protein to reduce DHT sensitivity in hair follicles.

      community Adrogens and Covid-19

      in Treatment  8 upvotes 4 years ago
      The possible increased risk of severe Covid-19 cases in men due to higher androgen levels, and how taking medications such as finasteride, dutasteride, spironolactone, enzalutamide, or canabidiol might help mitigate the severity of the disease.

      community Best Treatment In The Pipeline?

      in Chat  15 upvotes 4 months ago
      New treatments for AGA are emerging, including pyrilutumide, gt0029, scube3, kx-826, and pp405. Verteporfin is mentioned as a promising option.

      community Finasteride increase in Estradiol?

      in Update  17 upvotes 8 months ago
      A user experienced increased estradiol, nipple tenderness, and ED after taking finasteride. They are considering dose reduction to mitigate these effects.

      community 1 yr in! Fin/Min/Dermaroll/Keto

      in Progress Pictures  78 upvotes 1 year ago
      The user, InternationalTutor92, shared their progress pictures after using a combination of finasteride, minoxidil, keto shampoo, and dermarolling for a year. They mentioned that their hairline on the left side has improved, and they did not experience any side effects from the treatments.

      community Rosemary oil's potency as a dht blocker

      in Research/Science  65 upvotes 10 months ago
      Rosemary extract showed high inhibitory activity against DHT, similar to finasteride and dutasteride, but the conversation includes skepticism about its effectiveness in humans since the study was done on mice and rosemary oil is often considered ineffective based on personal experiences. Some suggest trying rosemary oil alongside other treatments, while others emphasize the difference between the extract used in the study and the oil.

      community Does CosmeRNA target the root cause of MPB?

      in Chat 1 year ago
      . CumsOnYourFeet69 has been discussing a new treatment called CosmeRNA which claims to target the root cause of male pattern baldness, and is considering using it in conjunction with Minoxidil instead of Finasteride due to possible side effects. Replies have highlighted that the efficacy of this treatment is still unknown, but it could be used as an effective maintenance option if successful.

      community Blood DHT Levels – before and after creatine

      in Research/Science  41 upvotes 1 year ago
      The impact of creatine on DHT levels, and whether it could cause accelerated male pattern baldness (MPB). The user taking a 5 alpha reductase inhibitor found that their DHT levels actually reduced despite taking creatine for nine weeks. Replies suggested looking into testosterone levels as well and debating the safety of creatine use in relation to MPB.

      community KX-826 Pyrilutamide1% coming soon

      in Update  152 upvotes 2 months ago
      KX-826 Pyrilutamide 1% is launching soon, and users are discussing its potential benefits and drawbacks compared to other treatments like Minoxidil and finasteride. Some users are skeptical about its effectiveness, while others are hopeful it will be a safer alternative.

      community Has anyone used the new liposomal topical fin from Hasson and Wong?

       6 upvotes 8 years ago
      The conversation discusses a new liposomal topical finasteride from Hasson and Wong, available in Canada and Italy, soon in the US, costing $40/month. It claims to reduce scalp DHT by 50% without affecting serum DHT, potentially benefiting those who can't tolerate oral finasteride or RU58841.

      community Hair Loss Results After 8 Months of Dutasteride

      in Progress Pictures  227 upvotes 4 days ago
      The user experienced increased hair density after 8 months of using dutasteride and 6 months of oral minoxidil. Some users joked about side effects, while others discussed the effectiveness of various treatments like finasteride and rosemary oil.

      community Hair looks extremely thin under sunlight!

      in Chat  26 upvotes 3 weeks ago
      A 22-year-old male experiencing diffuse thinning is using oral minoxidil and finasteride but notices his hair looks thin in sunlight. Suggestions include using hair products, considering topical minoxidil, addressing seborrheic dermatitis, and possibly trying dutasteride or a hair transplant.

      community Hair Loss Due To Chlorine and Hard Metals In Water?

      in Research/Science  1 upvotes 3 weeks ago
      Hair loss possibly caused by chlorine and heavy metals in water was addressed by using a shower filter, ketoconazole shampoo, and PRP sessions, which stopped the hair loss but did not lead to regrowth. Other users suggested similar experiences and solutions, emphasizing the importance of a good water filter and patience for potential regrowth.

      community Hair Loss Treatments and Hair Transplant

      in Progress Pictures  4 upvotes 3 weeks ago
      The user is experiencing hair loss and is using oral finasteride, considering adding RU58841 and microneedling, and planning a hair transplant. They are seeking advice on whether to wait for treatment results or proceed with the transplant.

      community Hair loss steps, guide to beginners or anyone experiencing hair loss

      in Treatment 3 weeks ago
      The conversation discusses a hair loss treatment regimen involving finasteride, dutasteride, spironolactone, bicalutamide, oral estradiol, microneedling, and minoxidil. The regimen aims to reduce androgenic alopecia by blocking DHT and androgens, with a caution about potential feminizing effects.

      community Hair follicle cloning is already possible

      in Chat  38 upvotes 4 weeks ago
      Hair follicle cloning is claimed to be possible but not widely available due to potential safety issues, such as cancer risks. Current treatments like finasteride and dutasteride are not effective for everyone, and there is frustration over limited access to these medications.

      community Hair Oils can be DANGEROUS and this is a case study. He lost all his hair.

      in Treatment  7 upvotes 4 weeks ago
      Hair oils can cause severe allergic reactions, as seen in Jermel Brown's case, leading to significant health issues and legal action for damages. Users discussed concerns about various hair oils, including Mielle and Kiehl's, with some experiencing hair loss and others using treatments like Minoxidil and Finasteride to address damage.

      community Hair loss 30F - thoughts on red light therapy vs min/fin?

      in Female  6 upvotes 1 month ago
      The conversation discusses hair loss treatments for a 30-year-old female, comparing red light therapy with minoxidil and finasteride. Concerns about hormonal impact and potential pregnancy are raised, with suggestions to consider spironolactone and microneedling, while emphasizing the importance of consulting a dermatologist.

      community hair loss treatment myths that perplex me

      in Treatment  8 upvotes 1 month ago
      Grapefruit juice doesn't significantly affect finasteride or dutasteride. Drinking topical minoxidil is risky; saw palmetto is less effective than finasteride or dutasteride for hair loss.

      community How does hair loss and recovery work?

      in Chat  12 upvotes 2 months ago
      Hair loss varies due to genetic sensitivity to DHT and other factors. Treatments discussed include finasteride, minoxidil, RU58841, and microneedling.

      community Hair re-growth in anorexia recovery

      in Female  11 upvotes 2 months ago
      Adequate nourishment and hormone replenishment helped with hair regrowth. Vegamour and Novo blends hair vitamins were also used but likely not effective alone.

      community Hair Cafe vid: low dose dutasteride ?

      in Finasteride/Dutasteride  6 upvotes 2 months ago
      The user is considering using 0.5 mg dutasteride once every 5 or 7 days due to side effects from finasteride and is also looking into topical liposomal dutasteride and pyrilutamide to stop hair loss. The goal is to stop hair loss, not regrow hair.

      community Hair feels like it’s getting worse

      in Chat  8 upvotes 2 months ago
      The user has been experiencing hair loss for years, tried ketoconazole shampoo without success, and has been on finasteride for 3 months but is unsure if it's working. A reply suggests waiting 6-12 months to properly assess finasteride's effectiveness.