Topical finasteride results in plasma levels 100 times lower than oral finasteride, potentially reducing systemic side effects. Users report similar efficacy with fewer side effects, suggesting a preference for topical application.
The conversation discusses the potential for high doses of dutasteride to completely inhibit scalp DHT and speculates whether this could cure baldness when combined with a topical antiandrogen. Specific dosages mentioned are 0.5 mg reducing scalp DHT by 55% and 2.5 mg by about 79%.
The user "DaysonDadum" shared their progress pictures after using finasteride and minoxidil for 10 months, along with regularly using Nizoral. They experienced positive results with no noticeable shedding and no side effects. Other users in the conversation asked about dosages and brands of the treatments.
The user shared their experience with Finasteride and Dutasteride for hairloss. They initially had success with Finasteride but switched to Dutasteride after experiencing shedding, which continued, and are now considering a hair transplant.
Switching from finasteride to dutasteride may be more effective for hair regrowth due to dutasteride's stronger enzyme inhibition, but combining both drugs could enhance results. Some users report better outcomes with dutasteride, while others recommend a gradual transition to prevent potential hairloss.
Creatine may increase scalp DHT without affecting serum DHT, potentially speeding up male pattern baldness (MPB) for those genetically prone. Treatments mentioned include Minoxidil, finasteride, and RU58841.
Hairloss treatments, specifically the use of Alfatradiol as an over-the-counter topical 5AR inhibitor that has been shown to be effective in stopping hairloss without side effects. Other treatments discussed include Minoxidil, finasteride and RU58841.
Dr. Oscar Muñoz's hairloss treatment tier list suggests oral minoxidil and finasteride are highly effective, while topical treatments like RU58841 and microneedling are less effective. Users discuss the effectiveness of various treatments, with some favoring oral options for their practicality and higher response rates.
Heavy nicotine use can lead to hair thinning and loss, but quitting can reverse these effects. The user noticed significant hair regrowth after quitting vaping.
Bryan Johnson shared his hairloss treatment, which mainly relies on minoxidil and finasteride. Some users are skeptical of his results, while others appreciate his efforts in anti-aging and hairloss research.
User obsessed with hairloss prevention shares collection of treatments, including oral and topical finasteride, minoxidil, dermapen, and more. Others suggest adding RU58841, laser helmet, and PRP, while some advise dropping certain treatments for long-term manageability.
Potential treatments for hairloss, including Minoxidil, finasteride, RU58841 and various upcoming pharmaceuticals, gene editing and cloning. It is suggested that a cure, if found, would be highly profitable due to the large number of people affected by hairloss globally.
A user's 20 year journey with hairloss and the treatments they have used to manage it, including finasteride, minoxidil, a custom Strut Blend of Dutasteride, Minoxidil, Tretinoin, and Biotin, Nizoral shampoo, multivitamins, Vitamin D, B Complex, Dim, Clomid, exercise, diet, laser helmet, Toppik dark brown, and topical Finasteride. The user also talks about their successful life, lack of desire for children and high sperm count due to Clomid.
A user shared their 2+ years progress on Oral Dutasteride and Sublingual Minoxidil for hairloss. Another user asked about the form of Minoxidil used sublingually.
Hairloss therapies focusing on hair follicle sugar metabolism and aldose reductase. Potential treatments include magnesium supplements, avoiding high glycemic index foods, and antioxidants.
For hairloss, start with Finasteride, Minoxidil, Ketoconazole shampoo, and Microneedling. For severe cases, consider Dutasteride, oral Minoxidil, or hair transplants.
The "Big 3 Stack" for hairloss treatment, which includes Minoxidil for hair density improvement, Ketoconazole shampoo for enhancing hair volume and thickness, and Finasteride for blocking hairloss causing hormones. Microneedling can boost Minoxidil's effects.
A user's journey with hairloss and their use of topical finasteride, minoxidil and pyri/minoxidil ratio treatments to attempt hair regrowth. Replies focused on offering support and advice while sharing personal experiences with different treatments.
People notice more young individuals experiencing hairloss and discuss possible reasons, such as diet, hormones, and stress. Some treatments mentioned include finasteride, dutasteride, and minoxidil.
Stopping minoxidil causes significant hairloss, as continued use is necessary for maintaining gains. Combining minoxidil with finasteride may help maintain hair, but both treatments are typically lifelong commitments.
Some people find topical minoxidil effective for hairloss, but oral minoxidil doesn't work for them, possibly due to absorption issues. Others have had better results with oral minoxidil, suggesting individual responses vary.
User shared 7-month progress of hairloss treatment, using daily 1mg Fin, 2x Min, monthly micro-needling, and ketocoz shampoo. They advise focusing on haircare, diet, and mental health after establishing a routine.
How Finasteride and Dutasteride help reduce hairloss by reducing the amount of DHT in scalp areas, as well as discussing factors such as sensitivity to DHT, 5α-reductase expression in different parts of the hair follicle, and scalp tension.
A user's success in treating their hairloss with 2x daily topical dutasteride and minoxidil, as well as the potential for using less frequent application of topical dutasteride due to its long half-life.
There have been no new effective hairloss treatments since finasteride, despite technological advancements. Current treatments include finasteride, minoxidil, and RU58841, with ongoing challenges and potential future solutions in research.
A user has been using minoxidil for hairloss and is seeing improvement. Some suggest adding finasteride or dutasteride for better results, but the user is concerned about side effects.