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      community A little over two years on Dut

      in Finasteride/Dutasteride  59 upvotes 1 month ago
      A 23-year-old male has been using Dutasteride for over two years to address hair thinning, with some success in temple regrowth but continued thinning on top. He is considering adding Minoxidil to his routine and is contemplating lifestyle changes like quitting smoking and drinking to improve hair density.

      community Pyrilutamide ,the molecule’s true nature

      in Research  302 upvotes 3 months ago
      Pyrilutamide is a selective AR antagonist with a high binding affinity, making it effective in competing with DHT for androgen receptors. The 1% concentration is more effective than the 0.5%, but the latter may suffice for mild hair loss; the drug is considered a good option for those avoiding 5AR blockers due to side effects.

      community Crown update 1 month - Oral min & Oral fin

      in Update  69 upvotes 4 months ago
      User is 1.5 months into using oral minoxidil and finasteride for hair regrowth, along with dermarolling. They report good progress and seek advice on whether new hairs will thicken.

      community Ketoconazole mesotherapy plausible?

      in Ketoconazole  9 upvotes 6 months ago
      The conversation discusses using ketoconazole, an anti-androgen, for hair loss and whether mesotherapy with dermarolling could enhance its absorption into the scalp. The user questions if the typical 2% ketoconazole shampoo dose would be effective when used after dermarolling to target androgen receptors in the scalp.

      community 15 years of finasteride/minoxidil

      in Update  194 upvotes 6 months ago
      A user shared a 15-year experience using minoxidil and finasteride for hair loss, stating that despite never missing a dose, their hairline continued to recede slowly. Other users suggested that the hair loss might be exacerbated by the use of steroids and recommended considering other treatments like dutasteride and RU58841.

      community Just started my third month of fin min

      in Treatment  148 upvotes 9 months ago
      A user, aged 32, is treating hair loss with oral finasteride, topical minoxidil, Vitamin D3, and magnesium. They shave their head, condition daily, and wash their hair every three weeks.

      community Are there ever going to be any oral DHT blocking treatments in the future?

      in Product  6 upvotes 1 year ago
      The discussion revolves around the need for future oral DHT blockers for hair loss treatment that don't have the side effects of current options like Finasteride and Dutasteride. One user suggests that the future of hair loss treatment will likely be topical anti-androgens, as they can target hair follicles without affecting the entire system.

      community Progress Pics – Minoxidil + Derma Rolling

      in Progress Pictures 1 year ago
      This conversation is about the user "Such_Ad7910" sharing progress pictures of their hair loss treatments, which include minoxidil and derma rolling. They recently got a prescription for finasteride to further help with their hairline, and multiple people have commented urging them to use it.

      community HLT Megathread on HMI-115 (key takeaways in comments)

      in Research/Science  38 upvotes 1 year ago
      HMI-115, a newly discovered hair loss treatment that could potentially be effective for those with diffuse thinning and telogen effluvium. It is based on prolactin receptor antagonist signaling and has already undergone Phase I trials in women, with potential commercialization by 2027.

      community 22M results after 1 year of fin 1.25mg/day

      in Progress Pictures  794 upvotes 1 year ago
      A user's results after using finasteride (1.25mg/day) for one year, which included improvements to their hair and skin as well as some side effects such as decreased libido and watery semen. They also mentioned they stopped taking creatine around the same time.

      community Kintor’s GT20029 Phase 1 success

      in Update  73 upvotes 1 year ago
      Kintor's GT20029, a treatment for hair loss, has completed Phase 1 successfully, showing promise as an androgen receptor degrader that could potentially regrow hair. It is considered more effective than Pyrilutamide, with infrequent dosing and minimal systemic absorption.

      community discouraged about pyrilutamide

      in Research/Science  11 upvotes 2 years ago
      Discouragement regarding Pyrilutamide, a drug in development for hair loss, and the potential side effects of Finasteride. People discussed anecdotal experiences with Pyrilutamide as well as suggestions to wait out Phase 3 trials before making any conclusions.

      community My Hairline journey. The first photo taken is the day I took the pill. No date specific just know I’ve been on finasteride 22 months. 2 years November 14th. ASK ANYTHING. Oh yeah started minoxidil a year later. Once every day or every other day super inconsistent and never really use 1ml, maybe half

      in Progress Pictures  326 upvotes 2 years ago
      . Fin from Inhouse This user has been taking finasteride for 22 months and minoxidil for 1 year to reduce hair loss, with apparent success; they have also avoided tight cornrow hairstyles to further protect their hairline.

      community Pyrilutamide update number 2 - 2 week use

      in Update  174 upvotes 2 years ago
      An update on the use of Pyrilutamide, a new drug for hair loss, which has resulted in no shedding or testicle ache; other users have questioned the science behind this and shared their own experiences with Finasteride, Minoxidil, and microneedling.

      community Why is no one talking about redensyl?

      in Question  57 upvotes 4 years ago
      Exploring the effectiveness of redensyl, a hair loss treatment, compared to minoxidil and finasteride. People shared experiences using redensyl and products containing it, such as The Ordinary Hair Serum.

      community Alternative keto shampoo to nizoral?

      in Ketoconazole  4 upvotes 1 month ago
      The conversation is about finding an alternative ketoconazole shampoo to Nizoral due to its strong smell, with suggestions including Intelligent shampoo and Sons brand. The discussion also touches on the effectiveness of ketoconazole for dandruff and hair loss, with some users recommending prescription options for higher concentrations.

      community Oral Minoxidil Eyelashes Are Insane

      in Minoxidil  288 upvotes 2 months ago
      Oral minoxidil can significantly increase eyelash length and thickness. Users report mixed results on hair growth, with some experiencing increased body hair.

      community Am discouraged, tried just about everything....

      in Chat  2 upvotes 4 months ago
      The user has tried finasteride, minoxidil, dutasteride, microneedling, retinol, topical finasteride, and ketoconazole for hair loss but continues to experience hair recession. They are considering adding oral minoxidil or RU58841 and are unsure about the next steps.

      community Topical Finasteride 1 year results

      in Progress Pictures  250 upvotes 5 months ago
      A 31-year-old male used topical finasteride for a year, reducing hair loss significantly with no side effects. Another user suggested adding minoxidil and using oils for better results.

      community Is this broscience? From More Plates, More Dates

      in Research/Science  22 upvotes 8 months ago
      The conversation discusses whether finasteride's reduction of DHT and increase in scalp testosterone contribute to hair follicle miniaturization. Some participants argue testosterone does not cause miniaturization, while others suggest that even with reduced DHT, other androgens like testosterone may still contribute to hair loss.

      community Just had this wild thought come into my head.

      in Satire  403 upvotes 9 months ago
      The conversation is about the debate over the existence of Post-Finasteride Syndrome (PFS) and its symptoms, with some users skeptical about PFS and others discussing side effects like erectile dysfunction and gynecomastia from hair loss treatments like finasteride. Specific treatments mentioned include finasteride, viagra, and a joke about using a popsicle stick for erectile support.

      community 1.5 years fin plus almost 3 years min, I think I’ve definitely made progress but I’m still not where I want to be, advice?

      in Progress Pictures  130 upvotes 10 months ago
      The user has been using finasteride for 1.5 years and minoxidil for almost 3 years for hair loss, and has seen some maintenance of hair but not significant regrowth. Suggestions from others include switching to dutasteride, trying oral minoxidil, and considering microneedling or hair fibers for better appearance.

      community PYRILUTAMIDE PHASE 3 RESULTS : No statistical significance

      in Research/Science  123 upvotes 11 months ago
      The phase 3 trial results for Pyrilutamide showed no significant difference from the control treatment in increasing hair count, leading to the company halting its development. Users discussed their disappointment and skepticism about hair loss treatments, with some mentioning other treatments like Minoxidil, Finasteride, and RU58841.