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The conversation discusses a new liposomal topical finasteride from Hasson and Wong, available in Canada and Italy, soon in the US, costing $40/month. It claims to reduce scalp DHT by 50% without affecting serum DHT, potentially benefiting those who can't tolerate oral finasteride or RU58841.

People discussing hair loss treatments emphasize the need for patience, as results from using finasteride and minoxidil can take 8-12 months or longer. Some users report early signs of improvement, while others experience continued shedding or slower progress.

A user experiencing significant hair loss started using Dutasteride, a drug typically used for prostate issues, and noticed a positive change in hair thickness and volume after 5 months. Other users in the conversation also shared their experiences and observations with Dutasteride, with one mentioning additional use of oral Minoxidil.

FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

A user's experimentation with various hair loss treatments, including medications and topical applications; as well as their desire to experience unusual sensations through the use of drugs.

Kitchen_Plastic_2847 had been fighting hair loss since 2019-2020 and was initially successful in regrowing his hair with finasteride. However, after contracting Covid three times back to back at the start of 2021, he started to lose his hair again. He found a new dermatologist who prescribed him oral minoxidil along with finasteride, but eventually decided it wasn't worth spending all the money to try and save his hair.

Topical minoxidil being a difficult product to apply, with users considering finasteride, RU58841, and oral minoxidil as alternative treatments for diffuse thinning hair. Other advice includes shaving the head in the first 3 months of using minoxidil and finding ways to apply it without saturating the hair.

A user's 6-month journey to treat their hair loss using 1mg finasteride twice daily, topical minoxidil, vitamin D3, keto diet, and microneedling. They experienced shedding at the end of month 3 but have seen progress in recent months despite this.

Hair loss treatments discussed include Minoxidil, Finasteride, RU58841, and Nizoral shampoo. Nizoral's effectiveness is debated, with some suggesting it works as a weak antagonist for androgen receptors, while others attribute its benefits to anti-fungal and anti-inflammatory properties.

The individual is experiencing hair loss and has a vitamin D deficiency, with levels at 7.49ng/ml or 26nmol/l. They are unsure if the deficiency is causing the hair loss and are seeking advice on vitamin D supplementation.

Clinical studies by Dr. Barghouthi and Dr. Bloxham indicate that Verteporfin, when used with FUE and FUT hair transplantation methods, shows promise in hair follicle regeneration and minimal scarring due to its ability to inhibit Yes-associated protein (YAP). Microneedling at depths of 3-3.5mm, combined with Verteporfin, could potentially reactivate dormant follicles, although the optimal dosage and application method are still under investigation. Concerns remain about the DHT sensitivity of regenerated follicles, highlighting the need for further research to optimize trauma levels and Verteporfin concentrations to achieve effective and scar-free hair regeneration.

The conversation humorously critiques hair loss treatments and the subreddit r/tressless. It mentions Minoxidil and finasteride as common treatments, with users reacting to a satirical roast by ChatGPT.

The user believes neck tension and poor posture contribute to hair loss, noticing improvements with yoga and muscle relaxation. Replies suggest androgenic alopecia as the cause and recommend exercises.

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

Hair loss treatments like minoxidil, finasteride, TDM-105795, and PP405. MIT is hosting a hackathon to find innovative hair loss solutions.

Many younger men are experiencing hair loss due to genetics, diet, stress, and lifestyle changes. Treatments like finasteride and minoxidil are mentioned, with some users noting improvements.

A user traveled to Turkey for a 5000-graft FUE hair transplant at ASMED Clinic with Dr. Koray Erdogan. They used finasteride before and after the surgery and shared detailed experiences, costs, and recovery tips.

The conversation discusses using a violet ray device for hair regrowth, citing a case where zinc ion treatments showed promising results. It also mentions similar devices like the Growcombr and niostem helmet.

The post and conversation discuss Verteporfin's potential as a hair loss treatment. It's shown promise in regrowing hair after transplants and might be effective with microneedling.

The method combines finasteride, minoxidil, intense leg exercises, and cold exposure to treat androgenetic alopecia. It aims to boost metabolism and reduce androgenic effects, enhancing hair growth.

A user's 11-month progress with hair loss treatment using Finasteride 1mg and Minoxidil 5%. The user is happy with the significant hairline regrowth and increased density, and is considering dermarolling for further improvement.

The user started losing their hair at 16 and got a hair transplant. They used Minoxidil and finasteride as treatments. The transplant has held up well and they have not experienced graft loss.

The post discusses microdosing finasteride to minimize side effects while treating hair loss. The user also mentions using minoxidil, biotin, and ketoconazole.

HMI-115 shows promising hair growth and thickening in just 2 months. Results are positive but need more time for confirmation.

A user reports significant hair regrowth after 3 months using finasteride, minoxidil, microneedling, Nizoral shampoo, biotin, and vitamins. They apply minoxidil twice daily, dermaroll twice a week, and use Nizoral shampoo twice a week.

User took 0.5mg Finasteride daily and 1x Minoxidil daily for 3 months, experienced positive hair growth and temporary side effects. Recommends sticking with treatment and adjusting dosage if needed.

A user's 6-month progress with treating their hair loss using finasteride, minoxidil, and Nizoral shampoo.

User discusses tight scalp causing hair loss and suggests treatments like scalp massages, PRP, saw palmetto, and eucapil. They share their experience with saw palmetto and eucapil and consider adding PRP and scalp massages for better results.

A hair transplant performed by Dr Bruno Ferreira in Portugal, which has improved the user's appearance and self-confidence. The user also mentioned taking finasteride for 5 years to help with their hair loss.