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GlossaryICH Guidelines

standardized protocols ensuring safety, quality, and efficacy of pharmaceuticals

ICH Guidelines, established by the International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use, are a set of standardized protocols aimed at ensuring the safety, quality, and efficacy of pharmaceuticals. These guidelines are widely adopted by regulatory authorities and the pharmaceutical industry to streamline drug development and approval processes across different countries, promoting global harmonization.

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community Did you notice Dr Rassman reply on microneedling on his website

in Microneedling 9 upvotes 1 year ago

The post discusses Dr. Rassman's advice on microneedling for hair loss, suggesting holding a Dr Pen with 36 needles in one spot for 10 seconds. The conversation includes differing opinions on this method, with one user explaining the importance of dipping the pen rather than swiping to avoid abrasions.

community why isn’t RU / pyri blamed for feminization, whereas spiro is?

in Treatment 1 year ago

User asks if spironolactone can stack with finasteride and pyrilutamide for hair loss treatment. They question why spironolactone is associated with feminizing effects, while RU/pyri/fluridil, which work similarly, are not.

community Does vitamin D deficiency actually cause hair loss? Has anyone actually grew back hair after fixing vitamin d levels?

in Chat 51 upvotes 1 month ago

Vitamin D deficiency can contribute to hair loss, but it is not the sole cause, and supplementation may not always resolve the issue. Treatments like finasteride and minoxidil are recommended for hair regrowth, with vitamin D and other supplements providing additional support.

community I’ve catch my hair loss early and I’m glad I took the measures to prevent it

in Chat 1 month ago

The conversation discusses a 17-year-old using finasteride to address early hair thinning, expressing pride in taking action to prevent hair loss. The user emphasizes the importance of starting treatment early and shares experiences with the hair loss community.

community 14 months into fin + min and my hair is way worse than before

in Chat 23 upvotes 1 month ago

The user experienced worsening hair loss despite using finasteride, minoxidil, and microneedling. Suggestions included reducing microneedling frequency, switching to oral minoxidil, adding tretinoin, and considering dutasteride.

community Vitamin D deficiency strongly correlates with androgenic alopecia, FMPH and telogen effluvium

in Research/Science 157 upvotes 1 month ago

Vitamin D deficiency is linked to hair loss, and supplementation with vitamin D can improve conditions like androgenic alopecia and telogen effluvium. Users discussed various dosages of vitamin D, emphasizing the importance of getting blood tests to determine the appropriate amount.

community Why a lot of people seems to hate on topical fin even though it suppresses more scalp dht?

in Chat 20 upvotes 1 month ago

Topical finasteride may reduce more scalp DHT but is seen as inconsistent and messy compared to oral finasteride. Users report mixed results with both forms, with some preferring oral for its convenience and consistent dosing, while others find topical effective but harder to apply.

community 9 month update 1st slide 2020 at my worst vs today. 2nd slide 9 months ago vs today. 3rd, wet hair. 4th, hairline. 5th, damp hair. 6th crown view. 7th, brushed back. 8 & 9, hair in high Summer humidity. 10th, no lighting.

in Progress Pictures 342 upvotes 4 months ago

User shared 9-month hair regrowth progress using a Fin/Min spray from HIMS, with additional microneedling. Other users praised the results and discussed the effectiveness of topical treatments.

community 11 weeks post op !!!! What you think ?

in Is this regrowth? 67 upvotes 4 months ago

A user shared their 11-week post-op hair transplant results, noting they use only vitamins, not minoxidil or finasteride. Replies suggest starting finasteride to maintain results, with mixed opinions on the current progress.

community 7 months on just topical finasteride (caretopic)

in Progress Pictures 52 upvotes 5 months ago

A user shared their 7-month progress using only topical finasteride for hair loss. They recently started a new, non-FDA treatment and will evaluate its effectiveness in 6 months.

community Caffiene shampoos left in for 2 minutes show comparable results to Minoxidil, and may work differently than Minoxidil, which can add to your stack, or work for non responders

in Research/Science 42 upvotes 5 months ago

Caffeine shampoos show comparable results to Minoxidil and may enhance its effects when used together. Caffeine can be detected in the scalp up to 24 hours after a 2-minute application, making it an affordable treatment option.

community 22M. 4 months on minoxidil 5%, 2x a day

in Progress Pictures 574 upvotes 7 months ago

A 22-year-old man shared his 4-month progress using minoxidil 5% twice daily for hair loss, showing thicker hair without using finasteride. Others commented on his good results and discussed their own experiences with hair loss and treatments.

community Better then Minoxidil( at least for me and my family)

in Treatment 42 upvotes 9 months ago

Capronium Chloride and Trichoxidil are suggested as better alternatives to Minoxidil for hair growth without heart side effects. The Japanese Dermatological Association recommends topical Minoxidil over Capronium Chloride.

community (comment) providing facts on people talking nonsense about minoxidil and BP-medicaton in general

in Research/Science 17 upvotes 11 months ago

Minoxidil is used for hair loss and sometimes for high blood pressure, but it's outdated for the latter. For high blood pressure, it's combined with a beta blocker and diuretic to manage side effects.

community Female, 30, PCOS diagnosis, MPB Norwood 2. Endo refuses to give anything other than Spironolactone. Feel like I’m at my wit’s end here.

in Female 56 upvotes 1 year ago

A 30-year-old female with PCOS and male pattern baldness is frustrated with her endocrinologist's recommendation of only Spironolactone and minoxidil, feeling that dutasteride, finasteride, and progesterone would be more effective. Other users suggest various online sources for treatments, warn against self-medicating due to potential risks, and recommend seeking a specialized endocrinologist or considering additional treatments like Inositol, Berberine, and dermaneedling.

community I'm considering scalp micropigmentation, has anyone here done it? If yes, did you regret it, how did it affect you?

in SMP 107 upvotes 1 year ago

User considers scalp micropigmentation (SMP) for hair loss. Mixed opinions shared; some regret it, others satisfied. Choosing reputable clinic and technician is important.

community Tell me I should be grateful, I’m trying not to shave it off. I’ve had about 2500 graft’s transplanted but I hate seeing my scalp.

in Is this regrowth? 101 upvotes 1 year ago

A user who had two hair transplants and is still concerned about their crown area, despite other people reassuring them that it looks normal. The advice given was to use Minoxidil, Finasteride, SMP, and to consider speaking with a therapist.

community ORAL MIN ,DERMAROLLING AND RU58841 PROGRESS 3 months (18,M)

in Progress Pictures 80 upvotes 1 year ago

The conversation is about an 18-year-old's progress with hair regrowth using oral Minoxidil, dermarolling, and RU58841 over three months, starting treatment after beginning to lose hair at 16. Participants are impressed with the improvement and encourage continued treatment.

community This is what Six years of DUT looks like

in Finasteride/Dutasteride 787 upvotes 1 year ago

User had success with dutasteride for hair loss after finasteride didn't work. Some experienced increased cholesterol and debated its relation to DHT.

community 2 months results: Dut 0.5mg / Oral min 2.5mg / Dut+PRP mesotherapy / microneedling

in Progress Pictures 87 upvotes 1 year ago

User's 2-month hair loss treatment includes Dut 0.5mg, oral min 2.5mg, Dut+PRP mesotherapy, microneedling, and other products. Dermatologist increased min dose to 5mg, expecting better results at 6-month mark.

community Starting the microneedling only journey. M35 with diffuse thinning. Derminator 2, keto, vitamins and castor oil.

in Microneedling 15 upvotes 2 years ago

A user is starting a microneedling regimen for hair loss, using Derminator 2, ketoconazole shampoo, castor oil, and multivitamins. They plan to provide monthly updates on their progress.

community 1M Minoxidil, Stemoyxidine, Alfatradiol, Microneedling

in Progress Pictures 32 upvotes 4 years ago

A user trying various treatments for hair loss, such as minoxidil, stemoyxidine, alfatradiol, and microneedling, with plans to add tretinoine and finasteride.

community Dermaroller vs dermastamp vs dermapen

in Microneedling 5 upvotes 2 weeks ago

Microneedling is debated for hair loss treatment, with some users finding it beneficial for minoxidil absorption and others skeptical of its effectiveness. Alternatives like finasteride and minoxidil are recommended, while tools like dermarollers, dermapens, and dermastamps are discussed for their pros and cons.

community Attention Finasteride / Dutasteride and Your liver

in Finasteride/Dutasteride 368 upvotes 3 weeks ago

Finasteride may cause elevated liver enzymes, potentially leading to liver issues, though this is rare. Users should monitor liver function and consider topical alternatives if liver sensitivity occurs.

community STOP LYING FOR LORD'S SAKE because you're misleading people who are trying their best

in Chat 185 upvotes 1 month ago

Some users believe people falsely claim hair restoration results from finasteride and minoxidil alone, while actually having hair transplants. Finasteride and minoxidil, often used with microneedling and nizoral, are effective for many, but results and opinions on dosages vary.

community 18 Months Minoxidil 5% Before & After

in Progress Pictures 508 upvotes 1 month ago

The user used Minoxidil 5% for 18 months, seeing improved hair density but no change in the crown area. They are cautious about using Finasteride again due to past gynecomastia.

community European Medecine Agency (EMA) review of Finasteride and Dutasteride

in Finasteride/Dutasteride 37 upvotes 1 month ago

Concerns about a potential ban on finasteride and dutasteride due to side effects, with users advocating for continued access and informed choice. Alternative treatments like pyrilutamide are also mentioned.

community How to Keep Your Hair on Steroids

in Treatment 16 upvotes 2 months ago

To minimize hair loss while using steroids, use finasteride or dutasteride and apply topical anti-androgens like RU58841. Avoid high doses of hair-toxic steroids; prefer testosterone, nandrolone, and boldenone.

community My boy Saul Goodman was on Minoxidil tabs too

in Satire 1883 upvotes 2 months ago

Saul Goodman was humorously depicted using high doses of minoxidil, finasteride, and spironolactone for hair loss. The conversation jokes about the unrealistic dosages and their potential side effects.

community (21) Finesteride hasn’t lowered my DHT after 8 months. Has anyone else experienced this?

in Finasteride/Dutasteride 24 upvotes 3 months ago

A user experienced no reduction in DHT levels after 8 months of finasteride, despite initial improvement in hair loss. They are considering switching to dutasteride but are concerned about potential side effects.