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      community A concise, easy-to-understand post on Androgenic Alopecia theory and its practical applications

      in Research/Science  92 upvotes 2 years ago
      The mechanism of Androgenic Alopecia and practical applications of treatments like Minoxidil, Finasteride, RU58841, dermarolling, scalp massages, anti-fungals, progesterone, estrogen, PPAR-γ activators, reducing oxidative stress, and scalp exercises. It explains why DHT is important in AA and how other factors might be involved such as hypoxia, increased DKK-1 expression, morphological changes to the scalp, skull growth during childhood/puberty, and blood flow.

      community Results so far on Finasteride and biotin

      in Progress Pictures  145 upvotes 2 years ago
      The conversation is about someone experiencing significant hair regrowth after 23 days on Finasteride and Biotin, with others suggesting additional treatments like Minoxidil and microneedling. Some doubt the speed of hair growth, while others believe Biotin isn't contributing to the results.

      community Results of Procyanidin B2 in clinical studies

      in Treatment  13 upvotes 4 years ago
      Procyanidin B2, a compound derived from Annurca apples, as a potential treatment for pattern hair loss. Several clinical studies were mentioned, which found that procyanidin B2 could increase hair growth, density, and keratin content. Other treatments such as Minoxidil, Finasteride, and RU58841 were not discussed.

      community Is GT20029 supposed to regrow hair as well?

      in Treatment  10 upvotes 1 year ago
      The user is considering switching from finasteride to dutasteride for hair loss. They are unsure if GT20029 can regrow hair, particularly on the temples. Another user mentions that regrowth on finasteride can take up to 2 years.

      community Genetics are so weird and unpredictable

      in Minoxidil  114 upvotes 1 week ago
      The user experienced male pattern baldness starting at 18, tried finasteride with no success, and switched to dutasteride, which halted hair loss. Minoxidil had no effect for them, while their brother, who didn't use AR inhibitors, maintained a juvenile hairline and successfully grew a beard with minoxidil, highlighting the unpredictable nature of genetics in hair loss and treatment response.

      community Got my DHT levels checked. 38 year old female. Still losing hair.

      in Female  10 upvotes 6 months ago
      A 38-year-old female is experiencing hair loss despite having almost undetectable DHT levels after using dutasteride. Suggestions include checking for PCOS, thyroid issues, adjusting diet, considering the impact of birth control, and trying treatments like tretinoin, redensyl, retinol, and minoxidil with derma stamping.

      community High DHT with finasteride. Help!

      in Finasteride/Dutasteride  6 upvotes 9 months ago
      Despite using 5% minoxidil, 0.1% finasteride, and other treatments like microneedling, MK-677, and Cialis, hair loss continues with high testosterone and DHT levels. Considering oral dutasteride but concerned about further increasing testosterone levels.

      community 3 months progress!! Fin + Min + Derma roller + Nizoral Shampoo.

      in Progress Pictures  561 upvotes 1 year ago
      The post discusses a user's successful hair regrowth after 3 months using 1 mg oral finasteride, oral minoxidil, weekly 1.5mm derma rolling, and Nizoral shampoo every other day, with no side effects. The conversation includes various responses, questions about the user's ethnicity and previous scalp condition, and suggestions for topical treatments.

      community I want to sacrifice my hair in the name of science

      in Chat  12 upvotes 1 year ago
      The conversation discusses various theories of hair loss, including DHT sensitivity and genetic factors, with the user willing to use themselves for research due to having a hair loss gene but different hair loss patterns compared to their brothers. Specific treatments were not mentioned in the provided text.

      community The "DHT" itch myth - it's more complicated

      in Product  6 upvotes 1 year ago
      A user found that scalp itch might be linked to inflammation rather than DHT alone and noticed hair improvement with certain cancer drugs. They also discovered that black seed oil relieved their scalp itch and are experimenting with a mix of essential oils for dry scalp, questioning if oils affect minoxidil absorption.

      community Kintor Pharma Announces Positive Top-line U.S. Phase I Trial Results of GT20029, the World’s First Topical Use PROTAC Compound

      in Research/Science  127 upvotes 1 year ago
      The conversation discusses positive initial trial results for GT20029, a topical compound for hair loss that degrades androgen receptors, potentially requiring only weekly application. Participants express hope for this treatment to be more effective and convenient than current options like Minoxidil, Finasteride, and RU58841.

      community HLT Megathread on HMI-115 (key takeaways in comments)

      in Research/Science  40 upvotes 1 year ago
      HMI-115, a newly discovered hair loss treatment that could potentially be effective for those with diffuse thinning and telogen effluvium. It is based on prolactin receptor antagonist signaling and has already undergone Phase I trials in women, with potential commercialization by 2027.

      community Pyrilutamide update: three months

      in Update  33 upvotes 1 year ago
      A user's 3-month experience with pyrilutamide to reduce hair shedding, and how it may not be strong enough to stop the thinning of their hairline. Other users mentioned the effectiveness of minoxidil and finasteride for treating hair loss.

      community May 2022 - September 2022. 4 month results on 2x daily minoxidil, finasteride, nizoral 2x weekly. Taken in the same office to try and keep lighting consistent.

      in Progress Pictures  639 upvotes 2 years ago
      Vat-R-U-Talkin-About: I'm not sure that wearing a hat would have an effect on either Minoxidil or Finasteride. It may be worth experimenting with not wearing one for a few weeks to see if it makes any difference. This conversation is about a user's progress pictures four months into taking minoxidil, finasteride, and nizoral twice weekly to treat hair loss; others shared their experiences and offered advice on how to improve the treatment.

      community I am actually regrowing my hairline without minoxidil or finasteride (mechanical stimulation)

       128 upvotes 6 years ago
      Regrowing hairline without the use of Minoxidil or Finasteride, and instead using mechanical stimulation such as Derma Roller, Nizoral, Zinc Pyrithione, Scalp Massage, Scalp Exercise, Fish Oil and other topical solutions. It is cautioned that there are risks associated with not using medically-prescribed treatments, but it is suggested to consider mechanical stimulation in addition to those prescribed treatments.

      community 2Y 5M on dut, ask me anything

      in Finasteride/Dutasteride  130 upvotes 1 month ago
      A user experienced significant hair regrowth using dutasteride without side effects, starting with finasteride and not using minoxidil or dermarolling. They attributed success to a unique genetic response to DHT blockers but did not share their full regimen, frustrating others.

      community Finasteride only - 1 year mark

      in Progress Pictures  200 upvotes 2 months ago
      A user shared their one-year progress using finasteride 1mg for hair loss, reporting no side effects, reduced shedding, and a thicker hairline. Other users discussed their experiences, asked questions about side effects, and noted the visible improvements in hair density and health.

      community Am discouraged, tried just about everything....

      in Chat  2 upvotes 3 months ago
      The user has tried finasteride, minoxidil, dutasteride, microneedling, retinol, topical finasteride, and ketoconazole for hair loss but continues to experience hair recession. They are considering adding oral minoxidil or RU58841 and are unsure about the next steps.

      community What's your option on complementary treatment

      in Product  3 upvotes 5 months ago
      The conversation discusses complementary treatments for hair loss while using finasteride and minoxidil, including scalp massagers, scrubs, coconut oil, and vitamin supplements. The user seeks opinions on these additional treatments.

      community 3 month update finasteride+minoxidil

      in Progress Pictures  642 upvotes 8 months ago
      The conversation is about a person showing significant hair regrowth after three months using finasteride and minoxidil. Some people congratulated the person, while others asked if they used derma rolling or oral minoxidil, to which they replied they used topical minoxidil.