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      community GT20029 China Phase II Trial For AGA Reached Primary Endpoint

      in Research/Science  136 upvotes 7 months ago
      The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.

      community Oral Min & Fin - 9 Months no results - diffuse thinner

      in Treatment  6 upvotes 7 months ago
      A 21-year-old has been using 0.4mg finasteride and 1mg oral minoxidil (increased to 2mg) for 9 months with no noticeable hair growth and worsening hair condition. They are considering stopping finasteride due to side effects and are seeking advice on other treatments.

      community 10 months CB and Oral Minoxidil

      in Progress Pictures  111 upvotes 7 months ago
      A person with Alopecia Areata on their beard is using CB-03-01 and oral minoxidil for treatment. Some users question the effectiveness of CB-03-01 for beard hair, suggesting that minoxidil alone may be responsible for any observed hair growth.

      community How does it feel to microneedle at 0.3mm?

      in Microneedling  17 upvotes 7 months ago
      The conversation discusses microneedling for hair loss, with one user trying 0.3mm daily without feeling pain and questioning its effectiveness. Another user suggests that 0.3mm is too shallow and recommends 0.5mm twice a week or 0.75mm once a week for hair growth.

      community Transition from Baby Hair to Normal Hair?

      in Finasteride/Dutasteride  33 upvotes 7 months ago
      The conversation discusses the slow transition from baby hair to normal hair while using finasteride and transitioning to dutasteride, with progress except for the crown area. It's mentioned that hair thickening can take years, with each growth cycle potentially making the hair thicker, and this process can span over 6 months or more.

      community WHEN does regrowth even happen?

      in Chat  11 upvotes 7 months ago
      The user changed their hair loss treatment in October/November, experienced increased shedding, and now sees no new hair growth, with a worsening condition and a possible bald spot. They also have severe seborrheic dermatitis, which may be affecting their scalp and hair loss.

      community Can Pyrilutamide use stopp Minoxidil gains

      in Chat  3 upvotes 7 months ago
      The conversation discusses whether using pyrilutamide would interfere with minoxidil's ability to regrow hair, considering pyrilutamide is seen as a maintenance drug that stops shedding, while minoxidil promotes hair growth but causes initial shedding.

      community Before and after 4 months minoxidl 6ml per week + microneedling (THE BEFORE IN IS THE RIGHT AND AFTER IN THE LEFT)

      in Progress Pictures  24 upvotes 7 months ago
      The user shared progress pictures showing hair thickening after 4 months of using minoxidil and microneedling, and has started taking finasteride. They are considering increasing minoxidil dosage if results are not satisfactory and are questioning whether their hair loss is genetic or self-induced from previous minoxidil use for beard growth.

      community 3 months on minoxidil 5% twice daily and micro microneedling, 2 months on topical finasteride (every other day) and bunch of supplements here and there.

      in Progress Pictures  106 upvotes 7 months ago
      The user has been using minoxidil 5% twice daily, micro-needling, topical finasteride every other day, and various supplements for 3 months to treat hair loss and has seen positive results. They also mentioned using hair growth tablets, biotin, zinc, and vitamins B and D, but not consistently.

      community Did i lose my chance or do i still have a chance?

      in Finasteride/Dutasteride  9 upvotes 7 months ago
      A 25-year-old has been using finasteride since around age 22 and is considering starting oral minoxidil due to scalp issues. They are concerned about the effectiveness of starting minoxidil at their current age and the impact of scalp redness on hair growth. Another person suggests that starting minoxidil at any time is fine but warns about the commitment required, as stopping it will result in losing regrown hair, unlike finasteride which slows hair loss progression.

      community Fin for 1 year+ no results, non-responder?

      in Finasteride/Dutasteride  10 upvotes 8 months ago
      A user has been on finasteride for over a year with minimal hair regrowth and is considering stopping it, despite no side effects. They are also planning a hair transplant and seeking additional hair growth treatments, while managing high testosterone and scalp issues like dandruff and oiliness.

      community Three months of consistent minoxidil.

      in Progress Pictures  3137 upvotes 8 months ago
      A user shared progress pictures after three months of using topical minoxidil for hair loss, planning to add dermarolling later. Some responders are skeptical of the rapid hair growth, while others are impressed or question the authenticity of the photos.

      community Started my hair loss treatment last summer

      in Progress Pictures  153 upvotes 8 months ago
      The user started treating hair loss last summer with 1mg finasteride, topical minoxidil from Costco, and weekly dermastamping. They plan to begin using dutasteride and oral 5mg minoxidil to further enhance hair growth.

      community Increasing Oral Minoxidil Dose Over Time

      in Research/Science  94 upvotes 8 months ago
      A user reports hair loss despite using minoxidil and plans to increase their oral minoxidil dose gradually while also taking finasteride, dermarolling weekly, and applying topical stemoxydine nightly. They shared a link suggesting that increasing minoxidil dosage can improve hair growth and thickness.

      community Is there any new drug that looks promising ?

      in Research/Science  25 upvotes 8 months ago
      The conversation discusses GT20029, a drug in Phase II trials that targets androgen receptors with minimal systemic effects, and TDM-105795, a growth stimulant with a different mechanism than minoxidil that may revive papilla stem cells. Both are potential new treatments for hair loss.

      community Is it true that most hair loss treatments fall into one of two categories? If not, what am I missing?

      in Treatment  4 upvotes 8 months ago
      Hair loss treatments are generally categorized as anti-androgens, like finasteride and RU58841, which prevent hair loss by targeting DHT, and growth stimulators, such as minoxidil, rosemary oil, microneedling, and LLLT, which promote hair growth by increasing blood flow and growth factors. The user is seeking to confirm these categories and understand if there are other treatments or mechanisms of action.

      community 1 month vs. 3 months. Oral min (3mg) and fin (1.1mg) update

      in Progress Pictures  53 upvotes 8 months ago
      A user shared their hair regrowth progress after using oral minoxidil (3mg) and finasteride (1.1mg) for 11 weeks, noticing significant improvement and no bald spots, with the side effect of increased eyebrow and eyelash growth. They plan to update again in 6-9 months and have inspired friends to try the same treatment.

      community 1mg Finasteride + 2.5mg Oral Minoxidil

      in Progress Pictures  17 upvotes 9 months ago
      A user shared their progress using 1mg Finasteride and 2.5mg Oral Minoxidil for hair loss, reporting no side effects and noticeable improvement in hair density and beard growth. They expressed gratitude for the support and hope to regain most of their hair.

      community Is IGF-1 the reason why some people don't respond well to min-fin treatment?

      in Treatment  6 upvotes 9 months ago
      A user who didn't respond well to minoxidil and finasteride is considering the role of IGF-1 in hair loss treatment effectiveness. They discuss the potential of using HGH to improve hair growth and other health issues, referencing several sources that suggest IGF-1 levels may influence hair loss and treatment response.

      community 7.5 months and fin, time for dut?

      in Finasteride/Dutasteride  12 upvotes 9 months ago
      The user has been using 1mg finasteride, 2% ketoconazole shampoo, vitamins, and growth shampoo for 7.5 months to treat hair loss and is considering switching to 0.5 mg dutasteride due to slight recession and persistent symptoms. Another user commented that the user's temples appear to have improved, especially in the latest photo.

      community Hypertrichosis Photos from Oral Minoxidil

      in Progress Pictures  266 upvotes 9 months ago
      A user shared their experience with oral minoxidil and finasteride for hair loss, taking 7.5mg of minoxidil and experiencing excessive hair growth all over their body without major side effects. Some users suggested lower doses for safety, while others shared their own experiences with hair growth in different areas and side effects.

      community 6 months hair update on Fin + Min

      in Progress Pictures  119 upvotes 9 months ago
      After six months of using topical minoxidil once daily and oral finasteride every three days, the user saw improvement in hair thickness, particularly at the crown, and some new hair growth at the hairline. They also used a 1.5mm dermaroller weekly, which they believe contributed to their progress.