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      community Libido on Finasteride

       4 upvotes 11 years ago
      The conversation discusses the effects of finasteride on libido, with the original poster experiencing a significant decrease in sexual desire after starting the medication. Other users share similar experiences and suggest potential remedies, including Vitamin E supplementation and lifestyle changes like avoiding pornography.

      community GT20029 China Phase II Trial For AGA Reached Primary Endpoint

       133 upvotes 2 years ago
      The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.

      community EMA is re-examining Winlevi (clascoterone at lower concentration)

       8 upvotes 1 year ago
      Clascoterone in Winlevi, a topical AR antagonist, is being re-examined due to concerns about HPA axis suppression in adolescents, but it's unlikely to be banned for adult use in androgenetic alopecia (AGA). The European Medicines Agency recommended refusing Winlevi for acne vulgaris, but this may not affect Breezula's approval for AGA.

      community Post GT20029 Syndrome any help?

      1 year ago
      The conversation discusses a user experiencing severe side effects after using GT20029, seeking help and donations. Other users suggest various remedies like hair combs, hairbands, garlic, fertilizer, and Vagisil.

      community Tressless ChatGPT AI is GOAT..

       30 upvotes 2 years ago
      Minoxidil, finasteride, and RU58841 are discussed as treatments for hair loss. Users find ChatGPT a helpful tool for researching these treatments.

      community Herb called ‘King of Hair’ as effective as Minoxidil?

       3 upvotes 6 years ago
      A popular Ayurvedic herb, referred to as the "King of Hair," may be as effective as Minoxidil for hair health. Some users are hesitant to switch from Minoxidil without human studies, while others report positive effects when using the herb alongside Minoxidil.

      community Breezula is a good alternative

       8 upvotes 4 months ago
      Clascoterone 5% solution (Breezula) is a promising alternative for androgenetic alopecia, showing continued hair growth with consistent use and no significant side effects. It may be suitable for those who cannot tolerate finasteride or dutasteride, especially when trying to conceive.

      community What are the alternatives to spironolactone for AGA?

       7 upvotes 1 year ago
      The user experienced side effects from spironolactone and is seeking alternatives for androgenetic alopecia (AGA), considering saw palmetto but unsure of its effectiveness. They are also exploring the possibility of using topical spironolactone, despite availability challenges.

      community Been off Tressless for a few years - what’s the latest on GT20029?

       17 upvotes 1 month ago
      GT20029 is an experimental topical treatment for male-pattern hair loss, showing promising results in Phase 2 trials and moving towards Phase 3. It aims to degrade androgen receptors in hair follicles, differing from treatments like finasteride and minoxidil.

      community GT20029 - Promising phase II results

       16 upvotes 2 years ago
      GT20029 showed significant hair growth and safety in phase II trials, with no adverse sexual events. Users are hopeful but concerned about future costs and systemic effects.

      community Gt20026 - the actual cure to hairloss?

       4 upvotes 6 months ago
      GT20026 is discussed as a potential treatment for hair loss that targets androgen receptors without affecting hormone levels, but it may not promote significant regrowth. It is expected to be available by 2028, with other treatments like Breezula and Clascoterone also mentioned.

      community Fallopia multiflora (Fo-Ti) for Hair Regrowth?

       3 upvotes 12 years ago
      Fo-Ti is discussed as a potential treatment for hair loss, but its effectiveness is questioned. Users express skepticism and caution about its use.

      community Anybody else trying shou wu chih or just straight fo-ti/he shou wu

       3 upvotes 3 years ago
      The conversation discusses using shou wu chih or fo-ti/he shou wu for hair loss, with OP noticing stiffer beard and body hair. A user warns about potential liver damage from fo-ti and questions the effectiveness of alternative medicine.

      community Bad news about GT20029 from Anagen Inc

       11 upvotes 3 years ago
      The conversation is about the difficulty in obtaining GT20029, a hair loss treatment, due to patent issues and the need to resort to group buys or Chinese labs for acquisition. Specific treatments mentioned include Minoxidil, finasteride, and RU58841.

      community GT20029. Kintor Pharma’s Product

       12 upvotes 3 years ago
      The conversation discusses GT20029, a compound by Kintor Pharma that degrades androgen receptors and is in trials, with potential as a hair loss cure. Another promising treatment mentioned is an antibody that blocks prolactin and has shown positive results in macaques.

      community An Uncontrolled Case Series Using a Botanically Derived, β-Cyclodextrin Inclusion Complex in Two Androgenetic Alopecia-Affected Male Subjects

       1 upvotes 5 years ago
      The conversation discusses a botanically derived treatment for androgenetic alopecia using ingredients like saw palmetto, green tea, and evening primrose, showing impressive results over 270 days. Concerns include the study's uncontrolled nature and potential product motivation, with suggestions to enhance absorption through derma rolling.

      community AH-001 another topical AR degrader beside GT20029, completed Phase I

       8 upvotes 10 months ago
      AH-001 is a new topical treatment designed to degrade androgen receptors, targeting the root cause of androgenetic alopecia without the side effects of oral treatments like finasteride. It has shown a strong safety profile and good local tolerability in early trials.

      community Best, possible, or experimental growth agonists that AREN'T MINOXIDIL.

       4 upvotes 5 years ago
      Various hair growth treatments were discussed, including microneedling, bimatoprost, setipiprant, stemoxydine, PGE2, CB-03-01, WNT Beta-Catenin upregulators, KY19382, topical estrogen, IGF-1, GH, MK-677, oral castor oil, fisetin, resveratrol, cetrizine, and lactic acid. Users shared experiences and sources for these treatments, with some expressing interest in topical solutions and others noting the lack of FDA approval or scientific evidence for certain options.

      community Water retention from topical minoxidil

       4 upvotes 4 years ago
      Topical minoxidil can cause water retention, making the face appear swollen. Switching from liquid to foam and reducing application frequency may help; using dandelion root extract as a diuretic is also suggested.

      community Anyone have experiences with Gugo Vine Bark shampoo?

       4 upvotes 2 years ago
      Gugo Vine Bark shampoo is discussed as a potential hair loss treatment, but opinions vary on its effectiveness. Some suggest using proven treatments like finasteride, minoxidil, or ketoconazole instead.