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      community Why Diffuse Thinning is Worse Than a Receding Hairline

      in Research/Science  149 upvotes 3 weeks ago
      Diffuse thinning is worse than a receding hairline as it affects the entire scalp, complicating styling and hair transplants. Treatments like finasteride, minoxidil, dutasteride, and RU58841 are mentioned, with some users noting improved hair density.

      community I feel so 🤡 right now, any advice?

      in Finasteride/Dutasteride  10 upvotes 3 weeks ago
      A user is seeking advice on using finasteride and minoxidil for hair loss after being unhappy with their dermatologist's advice. They are considering getting finasteride on their own due to prescription challenges.

      community hairloss in my 20s has ruined my life.

      in Research/Science  373 upvotes 4 weeks ago
      A person in their 20s is struggling with hair loss, using treatments like minoxidil and finasteride. Suggestions include self-improvement, therapy, hair transplants, and focusing on acceptance and confidence.

      community Update: Exactly one year of treatment

      in Progress Pictures  689 upvotes 1 month ago
      The user shared their one-year hair regrowth progress using topical Minoxidil, oral Finasteride, rosemary oil, and a silicone head massager, along with a healthy lifestyle and supplements. They are happy with the results but acknowledge some hair loss is still visible, especially when wet.

      community 1ish year on fin and no improvement

      in Is this regrowth?  86 upvotes 1 month ago
      The user has been using finasteride for over a year without improvement and recently started oral minoxidil. Suggestions include trying dutasteride and continuing minoxidil for potential regrowth.

      community 2 years on fin and amazed by the results

      in Finasteride/Dutasteride  132 upvotes 1 month ago
      Finasteride significantly improved hair density and reduced hair loss for the user over two years, with plans to switch to dutasteride for long-term benefits. The user experienced no shedding or side effects and obtained finasteride through a private prescription in the UK.

      community Exploring all options - Scalp tension theory

      in Research/Science  9 upvotes 1 month ago
      The conversation discusses the scalp tension theory as a potential factor in hair loss, alongside DHT, inflammation, and other mechanisms. Treatments mentioned include finasteride, minoxidil, and botox injections, with some users exploring additional methods due to varying effectiveness.

      community Discussion on Finasteride and life.

      in Chat  162 upvotes 1 month ago
      Finasteride can aid hair regrowth but may cause side effects like depression and sexual dysfunction. Users discuss experiences with finasteride, minoxidil, and RU58841, highlighting varied responses and the importance of informed treatment choices.

      community 14 months into fin + min and my hair is way worse than before

      in Chat  23 upvotes 1 month ago
      The user experienced worsening hair loss despite using finasteride, minoxidil, and microneedling. Suggestions included reducing microneedling frequency, switching to oral minoxidil, adding tretinoin, and considering dutasteride.

      community Why is everyone not directly advised Dutasteride?

      in Finasteride/Dutasteride  169 upvotes 1 month ago
      Dutasteride is less commonly prescribed for hair loss because it is not FDA-approved for this purpose, unlike finasteride, which is more accessible and preferred due to fewer side effects. Dutasteride may be more effective in reducing DHT but has a longer half-life and potentially more significant side effects.

      community What else is good. Besides the big 3.

      in Chat  36 upvotes 1 month ago
      Key treatments for hair preservation include minoxidil, finasteride/dutasteride, and microneedling, with additional options like specific shampoos, oils, biotin, zinc, tretinoin, clascoterone, and low-level laser therapy. Maintaining a healthy lifestyle, reducing stress, and addressing nutrient deficiencies can also support hair health.

      community 6th month. Should I switch to dutasteride?

      in Progress Pictures  11 upvotes 1 month ago
      The user has been using oral finasteride, topical minoxidil, and tretinoin cream for hair loss, with positive progress noted after six months. They are advised to continue their current regimen and consider additional treatments like derma rolling, while being cautious about switching to dutasteride due to potential side effects.

      community HT / Meds results are reverting, thinning, crazy shedding..

      in Progress Pictures  161 upvotes 2 months ago
      A user experienced significant hair shedding and thinning 10 months post-hair transplant despite using minoxidil and topical finasteride. They are considering switching to oral finasteride or dutasteride and are also dealing with scalp conditions like seborrheic dermatitis.

      community 3 Month Progress Pictures - Start -> Current

      in Progress Pictures  140 upvotes 2 months ago
      A user shared their 3-month hair loss treatment progress using 5% topical Minoxidil, Finasteride tablets, dermastamping, and ketoconazole shampoo. They reported significant improvement, advised consistency, and addressed questions about side effects and application methods.

      community 11 months progress pictures (24M)

      in Progress Pictures  269 upvotes 2 months ago
      A 24-year-old shared his 11-month hair regrowth progress using 1mg oral finasteride, Dr. Reddy's Minoxidil + Finasteride 5% topical solution, 2.5 mg oral minoxidil, microneedling, ketoconazole shampoo, and plans to switch to dutasteride and tretinoin. Users praised his progress, discussed hair regrowth strategies, and shared personal experiences with hair loss treatments.

      community Day 1 vs Day 168 (today) of defeating the norwood reaper

      in Progress Pictures  1499 upvotes 2 months ago
      The user achieved significant hair regrowth using topical 5% minoxidil and oral 1mg finasteride daily, especially around the temples. They experienced minimal side effects, with initial difficulty maintaining erections that resolved after a few weeks.

      community DHT is about to get smashed ….

      in Update  802 upvotes 2 months ago
      The conversation discusses hair loss treatments like topical finasteride with minoxidil, oral dutasteride, and essential oils. Oral treatments like dutasteride and finasteride are seen as more effective, though some prefer topicals to avoid side effects.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 3 months ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.