A user's hair regrowth journey involved a hair transplant and using RU58841, finasteride, and minoxidil, with side effects managed by other medications.
The user has been using a strong combination of hair loss treatments for 16 months, including Finasteride, Minoxidil, Dutasteride, and RU-58841, but their hair loss has worsened. They're questioning whether their high testosterone levels or residual scalp DHT are causing further hair loss, with a reply suggesting that even small amounts of DHT can cause hair loss if one is sensitive to it.
The conversation discusses the use of topical minoxidil and finasteride for hair loss, with some users combining them with oral treatments. Users share their experiences and opinions on effectiveness, cost, and convenience, with mixed views on whether topical or oral applications are superior.
Oral minoxidil may cause dry skin and dark eye bags but doesn't significantly age the skin. Topical minoxidil is toxic to cats, and some users prefer finasteride.
A user's success in treating their hair loss with 2x daily topical dutasteride and minoxidil, as well as the potential for using less frequent application of topical dutasteride due to its long half-life.
A person in their 20s is struggling with hair loss, using treatments like minoxidil and finasteride. Suggestions include self-improvement, therapy, hair transplants, and focusing on acceptance and confidence.
The conversation is about the debate over the existence of Post-Finasteride Syndrome (PFS) and its symptoms, with some users skeptical about PFS and others discussing side effects like erectile dysfunction and gynecomastia from hair loss treatments like finasteride. Specific treatments mentioned include finasteride, viagra, and a joke about using a popsicle stick for erectile support.
The conversation is about a person's slow progress in treating hair loss using finasteride, microneedling, testosterone replacement therapy, dutasteride, RU58841, and minoxidil. They experienced a significant hair shed after adding dutasteride.
The conversation discusses the impact of finasteride on sexual function, with many users reporting reduced libido and weaker erections despite continuing the treatment to prevent hair loss. Some users suggest checking hormone levels or switching to different dosages or treatments like dutasteride, while others share mixed experiences regarding the severity of side effects.
User shares 3-month progress on 1 mg finasteride daily, experiencing increased appetite as a side effect. They also use microneedling, topical minoxidil, and mielle rosemary mint scalp and hair strengthening oil.
User tried DIY Dutasteride Mesotherapy for hair loss due to unsatisfactory Finasteride results. Used mesotherapy injection gun and liquid dutasteride for better results and fewer side effects.
Hair loss treatments, specifically, discussing the effectiveness and side effects of finasteride, minoxidil, and RU58841 in various microdoses. It also includes an updated graph which provides information on how different doses affect DHT levels, scalp skin and serum androgen levels, as well as hair count.
FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.
The user's experience with Pyrilutamide for hair loss treatment, including their belief that it has sparked improvements in combination with other treatments such as Minoxidil and Finasteride. Another user was also hoping to see results from using Pyrilutamide alone.
Switching from finasteride to dutasteride may be more effective for hair regrowth due to dutasteride's stronger enzyme inhibition, but combining both drugs could enhance results. Some users report better outcomes with dutasteride, while others recommend a gradual transition to prevent potential hair loss.
Clinical studies by Dr. Barghouthi and Dr. Bloxham indicate that Verteporfin, when used with FUE and FUT hair transplantation methods, shows promise in hair follicle regeneration and minimal scarring due to its ability to inhibit Yes-associated protein (YAP). Microneedling at depths of 3-3.5mm, combined with Verteporfin, could potentially reactivate dormant follicles, although the optimal dosage and application method are still under investigation. Concerns remain about the DHT sensitivity of regenerated follicles, highlighting the need for further research to optimize trauma levels and Verteporfin concentrations to achieve effective and scar-free hair regeneration.
User shared 8-month progress with finasteride 0.5 mg 4 times a week and gluten-free diet for 5 months, improving hair loss. Plans to try microneedling soon.
A user in France is frustrated because three dermatologists refused to prescribe finasteride for their hair loss, suggesting it's not androgenetic alopecia (AGA) and offering expensive vitamin treatments instead. Other users suggest buying hair loss treatments like minoxidil and finasteride from various online pharmacies and considering a gender-affirming care physician for more understanding treatment options.
User experienced hair regrowth after 5 months on oral minoxidil and finasteride. Others praised the impressive results and mentioned the importance of combining treatments for best results.
A user expressed deep frustration and embarrassment about balding, especially at a friend's wedding, and mentioned using finasteride and minoxidil. Others shared similar experiences and offered support, with some suggesting therapy and hair treatments.
People notice more young individuals experiencing hair loss and discuss possible reasons, such as diet, hormones, and stress. Some treatments mentioned include finasteride, dutasteride, and minoxidil.
The conversation discusses whether individuals using hair loss treatments like Dutasteride (Dut) or Finasteride (Fin) should regularly check their hormone levels through bloodwork. Some argue it's important to monitor the effects of these medications on hormone levels, while others believe it's unnecessary if there are no side effects, citing cost and practicality concerns.
Donald Glover's (aka Childish Gambino) hair transplant results, which appear to be moderate with around 1000 grafts. Various users discuss the previous and current appearance of his hairline and speculate that he may have used medications like Minoxidil or finasteride to stabilize before getting a transplant.
The user started oral finasteride to improve hair regrowth, especially in the crown area, after only seeing some maintenance and regrowth with a regimen of micro-needling, topical Dutasteride, and Rogaine. They were initially concerned about side effects but decided to proceed after research and consultations.
Dutasteride may have fewer side effects than finasteride, with some users experiencing better hair maintenance. Experiences vary, with some preferring dutasteride for fewer side effects, while others see no significant hair improvement.
A user who was able to get dutasteride for free with their insurance, and another user mentioning that finasteride is only covered if it is used for medical reasons.
Finasteride is believed to slow down hair loss significantly, but may not completely stop it for everyone. Effectiveness and duration vary by individual, with some users experiencing positive results for over 10 years, while others see less benefit.
A 25-year-old male is concerned about his blood test results, particularly the low percentage of free testosterone, and is questioning whether starting finasteride for hair loss might worsen this issue. He also notes a slight vitamin D deficiency and lack of sleep before the test.