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      community Fun thought experiment about halting hair loss permamently

      in Research/Science  58 upvotes 6 months ago
      A user proposed genetically engineering scalp stem cells to stop androgen receptors from causing hair loss. Others discussed the feasibility, existing research, and potential issues with this approach, including targeting the correct cells and unintended effects.

      community GT20029 China Phase II Trial For AGA Reached Primary Endpoint

      in Research/Science  136 upvotes 6 months ago
      The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.

      community Topical is superior to oral in terms of results (my theory)

      in Finasteride/Dutasteride  61 upvotes 7 months ago
      The conversation discusses the use of topical minoxidil and finasteride for hair loss, with some users combining them with oral treatments. Users share their experiences and opinions on effectiveness, cost, and convenience, with mixed views on whether topical or oral applications are superior.

      community Finasteride 1.25mg 10 month Progress

      in Progress Pictures  149 upvotes 8 months ago
      The user shared a 10-month hair loss treatment routine using Finasteride, ketoconazole shampoo, and Red Light Therapy, noting significant progress and considering adding Dutasteride. They experienced initial side effects and changes in libido, but overall reduced hair shedding and regrowth, especially at the temples.

      community Progress - Min, Fin, and Nizoral.

      in Progress Pictures  344 upvotes 9 months ago
      The user shared progress photos showing hair regrowth after using Minoxidil, Finasteride, and Nizoral since mid-2023, and plans to replace derma rolling with Tretinoin. They discussed their routine, the initial shedding phase, and their experience with side effects, while others commented on the visible improvement.

      community Tretinoin can make it worse!!!

      in Chat  7 upvotes 1 year ago
      Tretinoin may enhance minoxidil's effectiveness for those not responding to minoxidil alone, but it could reduce efficacy for some who are already responding to minoxidil. Tretinoin requires careful use, including skin moisturizing and sun protection due to increased sensitivity.

      community Physician here AMA – 30M oral Fin 1-1.25 mg daily

      in Update  47 upvotes 2 years ago
      Hair loss treatments, specifically the use of finasteride, microneedling and potentially oral minoxidil. People discussed their experiences with finasteride, its effects on sexual behaviors, as well as potential solutions such as tadalafil or using other growth factor signal peptides for hope in curing male pattern baldness.

      community Can I mix finasteride in just water for topical?

      in Finasteride/Dutasteride  5 upvotes 2 years ago
      The conversation is about whether finasteride can be mixed with just water for a topical solution and if Isopropyl Alcohol and Propylene Glycol are necessary for effectiveness and faster drying. The user is seeking advice on the formulation of topical finasteride.

      community A concise, easy-to-understand post on Androgenic Alopecia theory and its practical applications

      in Research/Science  92 upvotes 2 years ago
      The mechanism of Androgenic Alopecia and practical applications of treatments like Minoxidil, Finasteride, RU58841, dermarolling, scalp massages, anti-fungals, progesterone, estrogen, PPAR-γ activators, reducing oxidative stress, and scalp exercises. It explains why DHT is important in AA and how other factors might be involved such as hypoxia, increased DKK-1 expression, morphological changes to the scalp, skull growth during childhood/puberty, and blood flow.

      community Going to try and reverse MPB naturally.

      in Treatment  55 upvotes 2 years ago
      A user is trying to reverse male pattern baldness (MPB) naturally by taking high doses of Vitamin D, improving diet, exercising, reducing stress, and other lifestyle changes, but plans to use finasteride if no results are seen in 60 days. Other users are skeptical, advising medical treatments like finasteride and warning against potential vitamin D overdose and the ineffectiveness of natural remedies for genetic hair loss.

      community 3yr Fin/Dut/Niz NW3+ —> NW1.5 Pictures with Writeup

      in Progress Pictures  32 upvotes 4 years ago
      A user improved their hair loss from NW3+ to NW1.5 over three years using a regimen of dutasteride, finasteride, Nizoral, biotin, and collagen. They experienced some side effects and adjusted dosages over time, and noted additional benefits like better skin and muscle gain.

      community Most Recent Interesting Hairloss Studies: 10% Minox vs 5% Minox / Radio Rrequency Treatment for AA / Topical Ketoconazole / PRP+Minox vs Minox vs PRP / Alopecia as a systemic disease

      in Treatment  92 upvotes 4 years ago
      Treatments for hair loss, such as topical minoxidil, platelet-rich plasma therapy with or without minoxidil, ketoconazole, non-abative radio frequency, natural products, finasteride and cortexolone 17 alpha propionate. The post evaluates the efficacy and safety of these treatments in various studies.

      community Redensyl Megathread !!!!

       42 upvotes 4 years ago
      Redensyl, which is a topical alternative to Minoxidil for hair loss. It may have advantages such as not making the hair greasy and lasting longer after discontinuing use than minoxidil. There are some positive reports from users, but also some negative ones, so it's unclear how effective this treatment will be in comparison to Minoxidil and other treatments like Finasteride or RU58841.

      community Finasteride won’t make all your problems go away

      in Finasteride/Dutasteride  323 upvotes 11 months ago
      A user shared that while finasteride improved their hair, it didn't solve all their insecurities, suggesting that self-acceptance is key. Others in the conversation expressed varying opinions, with some feeling that finasteride significantly boosted their confidence and quality of life, while others acknowledged it as a solution to hair loss but not a cure-all for other personal issues.

      community Watching my 23 y/o self deciding to do nothing about his thinning hair

      in Satire  1035 upvotes 2 years ago
      Hair loss and the various treatments available, including finasteride, minoxidil, dutasteride, dermarolling, RU58841, mesotherapy, Rogaine, and scalp massages. The discussion also includes regret for not starting treatment earlier and advice to start early in order to avoid further balding.

      community Is microneedling + minoxidil better than oral minoxidil

      in Chat  29 upvotes 1 week ago
      Oral minoxidil is considered more effective for hair regrowth than topical minoxidil, but it carries higher risks. Combining microneedling with topical minoxidil can enhance absorption, but oral minoxidil with microneedling shows significant results.

      community Exploring all options - Scalp tension theory

      in Research/Science  9 upvotes 3 weeks ago
      The conversation discusses the scalp tension theory as a potential factor in hair loss, alongside DHT, inflammation, and other mechanisms. Treatments mentioned include finasteride, minoxidil, and botox injections, with some users exploring additional methods due to varying effectiveness.

      community The ultimate Regimen for density and thick ess

      in Treatment  10 upvotes 1 month ago
      The regimen for hair loss includes topical finasteride, clascoterone, tretinoin, minoxidil, oral saw palmetto, beta-sitosterol, vitamin D, microneedling, and anti-fungal shampoo. Expected benefits are increased hair growth and density, with considerations for potential skin irritation and interactions between treatments.

      community 18-year progress pics. Fin only.

      in Progress Pictures  419 upvotes 1 month ago
      The user has been using finasteride for 18 years to manage hair loss and is considering starting minoxidil and possibly a hair transplant. Despite some regrowth, they are exploring additional treatments like dutasteride and oral minoxidil due to continued hair thinning.