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      community Dutasteride + Oral Minoxidil , 5 Months

      in Update  7 upvotes 5 months ago
      The post discusses using oral Minoxidil and Dutasteride for hair loss. Minoxidil improved hair growth with mild hypertrichosis, while Dutasteride caused severe acne, cognitive issues, and mild anxiety, leading the user to prefer Finasteride.

      community New Approach to Ketoconazole or just waste of time?

      in Ketoconazole  21 upvotes 5 months ago
      The post discusses using 2% ketoconazole shampoo as a competitive androgen receptor antagonist for hair loss, applied for 1.5 hours daily. The user questions its effectiveness and potential benefits compared to finasteride and minoxidil.

      community If dutesteride and oral minoxidil doesn’t work that’s it right?

      in Treatment  41 upvotes 6 months ago
      A user is experiencing ongoing hair loss despite using 0.5mg dutasteride and 2.5mg oral minoxidil for several years and is seeking advice. Suggestions include ensuring correct diagnosis, checking for other health issues, considering finasteride, trying topical antiandrogens, and consulting a dermatologist.

      community Breaking hair loss news! GT20029 is a resounding success!

      in Product  138 upvotes 7 months ago
      GT20029, a new hair loss treatment, shows promising results but only a slight improvement over placebo. People are cautiously optimistic, discussing its potential and combining it with existing treatments like Minoxidil and Finasteride.

      community Why is it that low testosterone causes hair loss as well? How can I be balding?

      in Chat  158 upvotes 7 months ago
      The conversation discusses the confusion over low testosterone potentially causing hair loss, with users sharing personal experiences and knowledge about hair loss treatments like Finasteride. Some users suggest that hair follicle sensitivity to DHT, not testosterone levels, is the key factor in balding, and others discuss the side effects of hair loss medications.

      community Creatine's effect on Hair Loss and DHT

      in Research/Science  98 upvotes 8 months ago
      A 21-year-old male managed to control his hair loss using Nizoral, RU58841, and finasteride, but experienced increased scalp itchiness after starting creatine, which subsided upon stopping creatine. Users shared mixed experiences on whether creatine affects hair loss, with some reporting negative effects and others seeing no change or defending its benefits.

      community Improve my stack (without Minoxidil)

      in Product  36 upvotes 11 months ago
      The conversation discusses improving a hair loss treatment stack without using Minoxidil. Microneedling is suggested, Alpecin is deemed ineffective, and there are concerns about the safety of Minoxidil compared to finasteride.

      community 15months hair regrowth results

      in Progress Pictures  6 upvotes 1 year ago
      The user saw hair regrowth after inconsistently using treatments like microneedling, peppermint and rosemary oils, ketoconazole shampoo, zinc pyrithione shampoo, and scalp massages, but stopped minoxidil due to heart palpitations. They plan to start a consistent treatment with a minoxidil and finasteride topical solution and will share results in six months.

      community Testosterone and hair loss seeming irrelevance

      in Research/Science  81 upvotes 1 year ago
      The conversation is about the role of testosterone in hair loss and the effectiveness of different treatments. The conclusion is that DHT is the main culprit for hair loss, and finasteride has been proven to work long-term in maintaining and regrowing hair. Testosterone may have a minor effect, but it is not the primary cause of hair loss.

      community Oral Minoxidil and Grapefruit Juice

      in Research/Science  96 upvotes 1 year ago
      The conversation is about the potential dangers of taking oral minoxidil and grapefruit juice together. Some users express concern about dangerous drug interactions, while others argue that grapefruit juice may inhibit the metabolism of finasteride. The conclusion is that grapefruit juice may make finasteride less effective, but it won't affect minoxidil.

      community Surprisingly thorough study on He-Shou-Wu/Fo Ti

      in Research/Science  14 upvotes 1 year ago
      He Shou Wu (Fo Ti) extract was found to prolong the hair growth phase, inhibit 5-alpha-reductase (like finasteride), reduce androgen receptors, and increase growth factors, potentially outperforming minoxidil in recovering hair follicle size after DHT exposure. Two compounds, emodin and TSG, are identified as responsible for these effects and warrant further investigation.

      community Depressed that topical dut+min is causing unwanted hair everywhere on my face. Is there anything can I do?

      in Minoxidil  21 upvotes 1 year ago
      The conversation is about a user experiencing excessive hair growth on their body due to using topical minoxidil and dutasteride. The suggested solutions are shaving off the excess hair or considering laser epilation. It is mentioned that dutasteride does not cause extra hair growth, while minoxidil can stimulate hair growth in unintended areas. The user is advised to lower the dosage, concentration, or frequency of use and only apply the treatment to the desired areas.

      community Hold up... CosmeRNA/SAMiRNA is actually coming real soon?

      in Technology  31 upvotes 1 year ago
      A user discovered CosmeRNA, a new hair loss treatment with clinical research backing, set to release soon. The conversation revolves around its potential effectiveness, cost, and how it compares to existing treatments like Minoxidil and Finasteride, with some users expressing hope for a side-effect-free option.

      community Anyone excited for CosmeRNA coming this month?

      in Product  171 upvotes 1 year ago
      CosmeRNA, a new hair loss treatment, is expected to release soon and may become part of the "big three" treatments alongside finasteride and minoxidil. It works differently from finasteride by targeting androgen receptors in hair follicles, potentially offering fewer side effects.

      community Kintor Pharma Announces Positive Top-line U.S. Phase I Trial Results of GT20029, the World’s First Topical Use PROTAC Compound

      in Research/Science  127 upvotes 1 year ago
      The conversation discusses positive initial trial results for GT20029, a topical compound for hair loss that degrades androgen receptors, potentially requiring only weekly application. Participants express hope for this treatment to be more effective and convenient than current options like Minoxidil, Finasteride, and RU58841.

      community My Pyrilutamide Experience Update 2 Part 2 PICS

      in Progress Pictures  54 upvotes 1 year ago
      The user's experience with Pyrilutamide for hair loss treatment, including their belief that it has sparked improvements in combination with other treatments such as Minoxidil and Finasteride. Another user was also hoping to see results from using Pyrilutamide alone.

      community Pyrilutamide update: three months

      in Update  33 upvotes 1 year ago
      A user's 3-month experience with pyrilutamide to reduce hair shedding, and how it may not be strong enough to stop the thinning of their hairline. Other users mentioned the effectiveness of minoxidil and finasteride for treating hair loss.

      community To all the young non-responders out there

      in Update  119 upvotes 1 year ago
      A 21 year old who has been taking various treatments for hair loss such as dutasteride, RU58841, minoxidil and finasteride with no results. Other users share their experiences of dealing with hair loss at an early age and offer advice on how to cope.

      community My experience and a discourse on “DUPA”

      in Chat  46 upvotes 1 year ago
      How diffuse unpatterned alopecia (DUPA) is not an invitation to self-diagnose oneself with aggressive AGA and that seeking a specialized dermatologist may help people experiencing hair loss. Treatment options discussed include topical clobetasol propionate, oral minoxidil, and discontinuing finasteride.

      community discouraged about pyrilutamide

      in Research/Science  11 upvotes 2 years ago
      Discouragement regarding Pyrilutamide, a drug in development for hair loss, and the potential side effects of Finasteride. People discussed anecdotal experiences with Pyrilutamide as well as suggestions to wait out Phase 3 trials before making any conclusions.

      community 1 month Pyrilutamide. A non responders story to everything.

      in Research/Science  218 upvotes 2 years ago
      My hairline, I am only 23. This conversation is about a user's experience with treatments for androgenic alopecia, including finasteride, dutasteride, RU, minoxidil, progesterone, melatonin, LLLT, oral minoxidil, and Pyrilutamide. They have tried many treatments over the course of two years without seeing much success, and they are considering getting a hair system as a last resort.

      community My barber is seriously making me lose hope

      in Minoxidil 2 years ago
      This conversation is about a user struggling with hair loss who has been told by their barber that minoxidil does not work and the only solution is to accept it. Other users have encouraged them to continue using finasteride and minoxidil, as well as look for another barber, since these treatments are scientifically proven to be effective in combating hair loss.