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      community Goodbye tressless. I’ve decided to give in to my hairloss.

      in Update  593 upvotes 1 year ago
      Kitchen_Plastic_2847 had been fighting hair loss since 2019-2020 and was initially successful in regrowing his hair with finasteride. However, after contracting Covid three times back to back at the start of 2021, he started to lose his hair again. He found a new dermatologist who prescribed him oral minoxidil along with finasteride, but eventually decided it wasn't worth spending all the money to try and save his hair.
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      community The ultimate regiment to reverse hairloss

      in Treatment  6 upvotes 1 year ago
      The conclusion of the conversation is that the user "Shakalakaplaka" shares their comprehensive hair loss regimen, which includes various treatments targeting different pathways such as DHT, inflammation, fibrosis, immune system, testosterone, gut problems, and scalp health. The effectiveness of the regimen is not confirmed, and some users express skepticism or request before and after pictures for credibility.

      community My Pyrilutamide Experience Update 2 Part 2 PICS

      in Progress Pictures  54 upvotes 2 years ago
      The user's experience with Pyrilutamide for hair loss treatment, including their belief that it has sparked improvements in combination with other treatments such as Minoxidil and Finasteride. Another user was also hoping to see results from using Pyrilutamide alone.

      community My Pyrilutamide Experience Update 2, Part 1

      in Update  61 upvotes 2 years ago
      The user's experience taking Pyrilutamide, a drug for hair loss treatment, and their use of it in combination with other treatments such as Minoxidil, Finasteride and RU58841. They have experienced positive results so far with no major side effects.

      community My Pyrilutamide Experience Photos

      in Update  593 upvotes 2 years ago
      A user's experience with Pyrilutamide, a topical treatment for hair loss that they used in combination with other treatments such as Minoxidil and Finasteride. The user experienced impressive results in a short amount of time.

      community Pyrilutamide real life results?

      in Research/Science  15 upvotes 2 years ago
      The results of using Pyrilutamide, a hair loss treatment available on the gray market, and other treatments such as Minoxidil, Finasteride and RU58841.

      community discouraged about pyrilutamide

      in Research/Science  11 upvotes 2 years ago
      Discouragement regarding Pyrilutamide, a drug in development for hair loss, and the potential side effects of Finasteride. People discussed anecdotal experiences with Pyrilutamide as well as suggestions to wait out Phase 3 trials before making any conclusions.

      community Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year

      in Research/Science  735 upvotes 2 years ago
      A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.

      community Pyrilutamide is literally my only hope

      in Chat  91 upvotes 2 years ago
      Considering treatments for hair loss, including Minoxidil, Finasteride, RU58841, Fluridil and Pyrilutamide. The user is weighing the risks of taking unapproved medication before it has been mass produced.

      community Starting Pyrilutamide BID. First dose was yesterday. Diffuse thinning. I will put my full regimen below.

      in Research/Science  89 upvotes 2 years ago
      A user's regimen to help with their diffuse thinning, which includes taking Pyrilutamide BID, 1mg finasteride daily, 2.5mg oral minoxidil daily, topical minoxidil since August 2021, LLLT every two days, topical fin, progesterone, melatonin, minoxidil (started one week ago), pumpkin seed oil and not dermarolling; other commenters suggested Nizoral for dandruff control and caution when using pre-mixed products with Pyrilutamide.

      community 5 Months Finasteride + Minoxidil

      in Progress Pictures  676 upvotes 2 years ago
      This user has achieved impressive results after 5 months of using Finasteride and Minoxidil, which appear to have stopped hair loss and stimulated new growth. They have also incorporated derma pen treatments and supplements such as Zinc picolinate and DMAE into their regimen.

      community Is Pyrilutamide the real deal and if so when will it actually be available?

      in Chat  21 upvotes 2 years ago
      Pyrilutamide, a potential hair loss treatment that is currently in development and may be available soon; an androgen receptor degrader which is also being developed as a potential treatment for hair loss; and the comparison between Pyrilutamide, finasteride, minoxidil, and RU58841.
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      community My nuclear protocol (scary but very effective)

      in Treatment  83 upvotes 2 years ago
      A hair loss treatment protocol involving topical and oral medications such as Minoxidil, RU58841, Finasteride, Dutasteride, Melatonin, Zinc, Vitamin B6, NAC, Caffeine, Biotin, Ginseng, and Semen; other treatments including Microneedling, Laser Helmet, Nizoral shampoo, Scalp Massage and supplements like Vitamin C, Vitamin D, Fish Oil, and Biotin; and the potential side effects of using this protocol.

      community Binding affinity of pyrilutamide!

      in Update  170 upvotes 2 years ago
      Pyrilutamide, a nonsteroidal antiandrogen drug under development for the potential treatment of androgenic alopecia. The conversation discusses its binding affinity to the androgen receptor and the timeline for possible availability after trials are completed in the United States and China.

      community Pyrilutamide… After using it for four days.

      in Research/Science  41 upvotes 2 years ago
      User tried Pyrilutamide for hair loss and noticed less hair fall initially, but experienced more hair fall after four days. Others advised to assess results after a longer period and consider increasing dosage for better results.

      community Don’t make the same mistake I did

      in Treatment  111 upvotes 2 years ago
      User noticed hair thinning at 26 and used minoxidil for 2 years with slight improvement. Stopping minoxidil led to dramatic hair loss, and others shared similar experiences, suggesting minoxidil and finasteride should be used consistently for best results.

      community Ingest topical minoxidil by mouth ?

      in Minoxidil  6 upvotes 2 years ago
      A user questions if ingesting topical minoxidil could be an alternative to oral minoxidil for hair loss. Another user reports success with this method, noting they saw results and experienced no adverse effects.

      community Topical melatonin/oral

      in Research/Science  12 upvotes 3 years ago
      The conversation discusses the potential positive effects of melatonin on hair growth. The original poster plans to try both oral and topical melatonin and is seeking recommendations for a good source.